Sentences with phrase «gene expression changes in»

Fascinating research from the lab of Mark Zylka, PhD, director of the UNC Neuroscience Center, suggests that chemicals designed to protect crops can cause gene expression changes in mouse brain cells.

RNA - seq technology offers a rapid and scalable approach to characterize how gene expression changes in response to experimental manipulations, and is applicable across a wide range of taxa.

Qu S, Olafsrud SM, Meza - Zepeda LA, Saatcioglu F. Rapid gene expression changes in peripheral blood lymphocytes upon practice of a comprehensive yoga program.

The same can be said for patterns of gene expression changes in the same brain region for different age frames.

«We saw frequent copy number changes, and gene expression changes in metastases that reflect a change in metabolism,» Siegel said.

He examined the gene expression changes in mice well before some of them developed advanced cancers.

When his team looked at gene expression changes in the mice, then applied them to humans with early stage cancer, the results revealed a breakdown of which patients have a high or low chance of survival.

They identified 60 genes that exhibited convergent evolution in CAM species, including convergent daytime and nighttime gene expression changes in 54 genes, as well as protein sequence convergence in six genes.

Scientists at Southern Methodist University, led by Professor and Chair of Biological Sciences Santosh D'Mello, have used RNA - Seq to conduct transcriptome profiling of gene expression changes in dying neurons.

Other labs have used DNA microarray analysis to characterize gene expression changes in this model.

The Plant Signaling investigation and Biological Research in Canisters (BRIC) 17 - 1 both study how the plants» gene expressions change in microgravity.

Not exact matches

There's better communication,» she told Inc.com in an interview, citing science that shows meditation changes the brain, immune system, and even gene expression.

The good news is that little tweaks in your diet, like adding foods that are high in long - chain omega - 3 fats, can change the expression of your genes.

This can lead to change in baby's physiology and gene expression.

They compared changes in gene expression in 37 of them who developed suicidal feelings with previously published work and with post-mortem samples of 26 men who had killed themselves.

Utilizing this very sensitive technique they were able to demonstrate significant changes in the expression of over 4000 genes.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

Within the cell, they can trigger changes in gene expression and biochemical reactions, among other things.

«Although they don't code for proteins, they fine - tune gene expression in response to dynamic changes in the environment.

The technology substantially expands our ability to change gene expression in cultured cells and animals..»

Scans showed remodeled DNA methylation patterns in the low - fat group, which changed gene expression associated with fat metabolism and inflammation in the liver; there was less fat accumulation and inflammation in the liver.

The overlap in gene expression changes when neural progenitor cells are infected by African or Asian strains of Zika virus.

Now, new research suggests changes at the epigenetic level — specifically alterations in proteins that affect gene expression, rather than genetic mutations — could be driving childhood ependymomas.

The authors describe dengue as inducing more robust changes in gene expression than either strain of Zika.

«It was a little eerie and a little scary to see how something as subtle as a nutritional change in the pregnant mother rat could have such a dramatic impact on the gene expression of the baby,» Jirtle says.

The direct methylation of the DNA changes the gene expression permanently if it takes place in the control regions of genes (so - called CpG islands), that have been made accessible by the modification of the histones.

In a new study published in Physiological Genomics, a team of U.S. researchers tracked in detail how this extreme makeover is controlled by changes in gene expressioIn a new study published in Physiological Genomics, a team of U.S. researchers tracked in detail how this extreme makeover is controlled by changes in gene expressioin Physiological Genomics, a team of U.S. researchers tracked in detail how this extreme makeover is controlled by changes in gene expressioin detail how this extreme makeover is controlled by changes in gene expressioin gene expression.

However, microgravity can reduce cell growth, alter gene expression and change the pattern of root growth — all aspects which critically affect plant cultivation in space.

The patterns of gene expression matched and often preceded physiological changes in the intestine, the researchers wrote.

The Epstein - Barr virus, which infects some 90 % of Americans, may cause changes in gene expression that dramatically increase a person's chance of getting lupus and six other autoimmune disorders, a new study by Harley, now a rheumatologist at the Cincinnati Children's Hospital Medical Center in Ohio, and colleagues shows.

Finally, the team identified a network of genes in these regions that exhibit changes in expression when the normal boost from serotonin is lacking, and these changes depended on how long the drug was given.

According to the researchers, this is the first study to link the extreme and rapid eating - induced changes of the Burmese python's intestines directly to changes in gene expression, and also the first to show how quickly gene expression changed.

This study could help us understand how changing messenger molecule tails could control gene expression in the context of regeneration.

They found similar changes in gene expression in the same genes with increased activity of glucose transporters in both the stem cells and the fat cells, Sen noted.

The genome - wide epigenetic changes clustered in certain chromatin domains and controlled «gene expression changes that specify different malignant traits, including the ability to form tumors,» McDonald said.

They found that gene expression is different at 209 sites in chronically lonely people and that many of those changes fit a pattern of elevated immune activation, inflammation, and depressed response to infection.

The researchers demonstrated that blocking the PGD enzyme genetically or with a pharmacologic inhibitor reversed the epigenetic reprogramming and malignant gene expression changes detected in distant metastases, and also strongly inhibited their tumor - forming capacity, with no effect on normal cells or peritoneal pancreatic cancer controls.

Scientists from the Biogerontology Research Foundation (BGRF), a UK - based charity founded to support aging research and address the challenges of a rapidly aging population, propose a new concept for signalome - wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data.

A growing body of evidence suggests that environmental stresses can cause changes in gene expression that are transmitted from parents to their offspring, making «epigenetics» a hot topic.

Hockemeyer says that it's unlikely to be another mutation, but rather an epigenetic change that affects expression of the telomerase gene, or a change in the expression of a transcription factor or other regulatory proteins that binds to the promoter upstream of the telomerase gene.

Scientists at The Scripps Research Institute (TSRI) have identified a molecule in the brain that triggers schizophrenia - like behaviors, brain changes and global gene expression in an animal model.

Evaluation of the levels of gene expression in these blood samples showed a distinct change in RA patients who had responded to treatment.

While nicotine and non-nicotine products both produced changes, e-cigarette products without nicotine resulted in even more gene expression changes than products with nicotine, Zelikoff said.

Still, he says it would be «reassuring» to see the study repeated with more subjects, and he notes that the work leaves unanswered which comes first, the loneliness or the change in gene expression.

One way for that to happen is through changes in gene expression, but changes in phosphorylation are equally effective,» explains Beltrao.

«We also found that reduced cohesin led to changes in the expression of genes involved in nerve cell development and the response to an immune signaling protein,» corresponding author Toshihide Yamashita says.

In collaboration with Yi Xing from UCLA, the team catalogued and analyzed how gene expression patterns in skin cells differed among the Esrp knockouts and found hundreds of significant changeIn collaboration with Yi Xing from UCLA, the team catalogued and analyzed how gene expression patterns in skin cells differed among the Esrp knockouts and found hundreds of significant changein skin cells differed among the Esrp knockouts and found hundreds of significant changes.

The researchers found that the blond hair commonly seen in Northern Europeans is caused by a single change in the DNA that regulates the expression of a gene that encodes a protein called KITLG, also known as stem cell factor.

A distinctive pattern of changes in gene expression occurs in those RA patients who have a good - response to a TNF inhibitor at three months, but not in non-responders

This gave us an unprecedented opportunity to chart changes in gene expression spanning the course of a lifetime.»