Sentences with phrase «gene expression during»

Muscle protein synthesis and gene expression during recovery from aerobic exercise in the fasted and fed states.

Intracellular calcium release and protein kinase C activation stimulate sonic hedgehog gene expression during gastric acid secretion.

We will then functionally test the ability of identified sequences to control gene expression during tooth development using transgenic reporter experiments in fish embryos.

Compared to PHWSC adipocytes, SGBS adipocytes showed not only greater induction of adipogenic gene expression during differentiation but also increased levels of UCP1 mRNA and protein expression.

Global analysis of patterns of gene expression during Drosophila embryogenesis.

Systematic determination of patterns of gene expression during Drosophila embryogenesis P. Tomancak, A. Beaton, R. Weiszmann, E. Kwan, S. Shu, S.E. Lewis, S. Richards, M. Ashburner, V. Hartenstein, S.E. Celniker and G.M. Rubin Genome Biology (2002) 3 (12): research0088.1 - 0088.14 Download entire paper in pdf format

K. K. Dill, K. Thamm, E. C. Seaver, Characterization of twist and snail gene expression during mesoderm and nervous system development in the polychaete annelid Capitella sp..

MiRNAs also confer robustness to systems by stabilizing gene expression during stress and in developmental transitions.

Comparative RNA - Seq based dissection of the regulatory networks and environmental stimuli underlying Vibrio parahaemolyticus gene expression during infection.

Integrating this new information into computational models, my colleagues and I predicted that about 5 percent of HARs function as noncoding RNAs, while most are enhancers that control gene expression during embryonic development.9

The findings reported in Nature Genetics indicate that genome architecture has important informational value for controlling gene expression during cell reprogramming, and is thus required for the specialized functions of a cell.

We find that gene expression during development is both remarkably dynamic and tightly controlled.»

I would like to research how chromatin modulation alters gene expression during early stages of differentiation using computational biology and experimental approaches.

The group of promoters, whose H3K4me3 levels were affected by combined chidamide and decitabine treatment, but not by either chidamide or decitabine treatment alone, was enriched with binding site motifs for PU.1, a transcription factor that activates gene expression during myeloid and B - cell lymphoid cell development15, 16 (Figure 5C).

In collaboration with Margarita Salas (CBM - CSIC), in bacteriophage φ29 we examine the transcriptional regulator p4 that functions as a switch between early and late gene expression during the infection cycle.

In addition to hinting at a link between depression and brain gene expression during development, there was also evidence of overlap between the genetic basis of depression and other mental illnesses.

Patricia Heyn (Neugebauer, MPG)-- «Nuclear architecture and gene expression during early zebrafish development» (2013)

Exposing S. pistillata to seawater with an elevated calcium concentration resulted in up - regulation of gene expression during the day relative to the night.

Researchers at Carnegie Mellon University have developed a new dynamic statistical model to visualize changing patterns in networks, including gene expression during developmental periods of the brain.

The team found deep conservation of certain processes that likely reflects similar underlying regulatory processes between mouse and man, but there were also significant differences in gene expression during kidney development, as well as in the timing, scale, organization, and molecular profile of key cell types and cell structures.

«We didn't set out to study the relationship between the epigenetic chromatin marks and gene expression during development, but rather to analyze the function of these marks in DNA processing.

«TIA - 1 is known for its ability to regulate gene expression during cellular stress,» says Hewett, who studies the processes that suppress the severe electrical storms in the brain, leading to seizures.

The new research focused on just nine genes, those most strongly associated with autism in recent sequencing studies, and investigated their effects using precise maps of gene expression during human brain development.

When that lab closed she went back to university, working in a biochemistry and molecular biology lab to study gene expression during wine making, but this contract, too, came to an end.

This program, resulting in shorter 3 ′ UTRs, is a characteristic of gene expression during immune cell activation and correlates with proliferation across diverse cell types and tissues.

Enzymes that chemically modify DNA, known as DNA methyltranferases, play critical roles in regulating gene expression during development, but their role in cancer formation is less clear.

MicroRNAs were already known to regulate gene expression during development.

Molecular studies of gene expression during long - lasting synaptic plasticity related to memory storage initially focused on the identification of positive regulators.

Not exact matches

Taylor and colleagues made this discovery by exposing fetal mice to BPA during pregnancy and examining gene expression and DNA in the uteruses of female fetuses.

The resulting transcriptional profiles cluster not by postpartum day, but by milk Na: K ratio, indicating that women sampled during similar postpartum time frames could be at markedly different stages of gene expression.

RNAs contained in this non-coding part act as regulatory molecules and have a large impact on gene expression: where in the body and when during development or adulthood genes are expressed.

Messenger RNA (mRNA) serves as an important intermediary during gene expression, by relating the genetic information of DNA to the molecular mechanisms involved in manufacturing proteins.

The Geneva neuroscientists» results thus reveal that during development, the various sensory pathways initially share a common gene expression structure, which then adapts to the activity of the organ attached to each sense.

«By observing neuronal gene expression in these distinct pathways during development, we detected common patterns, as if an underlying genetic language was bringing them together.»

«Our work suggests that fine - tuning messenger stability is an important mechanism orchestrating gene expression changes during normal brain development.»

Researchers have found that the expression of three key genes drops during the fasting - mimicking diet.

It will block transcription during gene expression.

But when the UPR was chemically activated, Bmal1 stayed low during both light and dark phases, which caused a phase shift in the expression of circadian genes.

«We found that simple changes have a powerful impact on gene expression,» Dean Ornish, founder and president of the Preventive Medicine Research Institute and clinical professor at the University of California, San Francisco (U.C.S.F.), said during a news conference.

In aging, this gene expression presumably occurs to compensate for the accumulation of protein damages; during diapause, the same genes may be activated to prepare the whole embryo to catch up with the interrupted development and be ready to hatch as the rainy season starts.

Several studies had already pinned some of the visible abnormalities in clones on the absence of vital molecules that turn gene expression on and off during fetal development.

During development, as an embryo forms differentiated tissues, liver cells, brain cells, muscle cells, the cells in those tissues begin to allow for the selective expression of genes contained in those same 3 billion nucleotides.

This is important, he added, because this technique is increasingly used for classifying diseases and their subtypes, understanding gene expression changes during development and tracking the progression of cancer.

In the new study, a team led by Vanessa Dumeaux during her time at McGill University examined links between gene expression in breast cancer tumors and in the bloodstream.

The researchers used the worm's genomic information to study how gene expression changed during regeneration.

«RNA controls splicing during gene expression, further evidence of «RNA world» origin in modern life.»

A study carried out by the Laboratoire Neurobiologie des Interactions Cellulaires et Neurophysiopathologie (CNRS / Aix - Marseille Université), in collaboration with clinicians from Marseilles Public Hospitals (AP - HM) and scientists from the Salk Institute in San Diego (US), has revealed a new gene that plays a crucial role during early development in humans and whose under - expression may induce certain autistic traits.

Another provocative observation from the new study was that transient gene expression events during brain development set up broad distinctions in neural fate between cells in different areas in the cerebral cortex.

Hutchinson - Gilford progeria is caused by a spontaneous mutation during conception in a gene called LMNA, which encodes a protein called prelamin A. Progeria patients experience a buildup of an abnormal version of prelamin A in their cells that, among other changes, distorts the nucleus and alters gene expression.

«Many genes that had changed their genetic expression also changed their degree of methylation during the development to mature muscle cells, which indicates a connection,» she says.