Sentences with phrase «gene expression patterns»

To understand immune suppression in mice with genetically distinct pregnancies, the researchers examined gene expression patterns in immune cells during infection.

The research also showed that gene expression patterns of individual tumors varied considerably, and could exceed the variation observed between different cancer types.

The researchers also found different gene expression patterns after the flu vaccination in younger and older people.

Consequently, the unique gene expression patterns in every tissue dictate its structure and function.

Identifying gene expression patterns in relation to the compound could facilitate the selection of the most appropriate patient cohorts for clinical development.

She and her colleagues propose that other replication inhibitors to fight cancer will also produce unique double strand break profiles, as gene expression patterns would dictate the locations of replication - transcription conflicts.

Then, she was more interested in the rapid change in gene expression patterns stimulated by environmental stress, which is anything but subtle.

The Core provides equipment and services to determine gene expression patterns in mouse and human tissues.

At each developmental stage, the researchers conducted single - cell RNA sequencing to identify unique gene expression patterns and assess the purity of individual cell populations.

This work shows the power of using the tools of computational genomics to analyze gene expression patterns for the purpose of elucidating the evolution of behavior.

Moreover, when analyzed with gene expression patterns of normal brain cells, the four GBM subtypes associate with different cell lineages.

Since regeneration recapitulates in broad strokes embryonic development, during which a complex multi-cellular organism develops from a handful of embryonic stem cells, the researchers began by comparing gene expression patterns between the two processes.

They examined the effect of meditation on gene expression patterns in both novice and regular meditators.

Comparison of the transcripts revealed that breast cancer cells with knockdown of ABL2 alone shared a similar gene expression pattern with that of the ABL1 / ABL2 double - knockdown cells (Fig. 6A and fig.

Recent advances in the understanding of cancer have led to more personalized therapies, such as drugs that target particular proteins and tests that analyze gene expression patterns in tumors to predict a patient's response to therapy.

Collectively, these results suggest that increased rates of DNA turnover have had little impact on altering gene expression patterns, since the majority of DNA turnover in these regions surrounding developmental genes has likely not interrupted regulatory element architecture.

Dr. Hardison noted that the opposite is also true: researchers need to take into account systematic differences in gene expression patterns between the species when considering the mouse as a model for humans.

Can we watch how gene expression patterns change over time during development for each subtype?»

Horvath and Tell's research is the first reported study to compare breast cancer subtypes and gene expression patterns associated with STAT3 in the tumors of human patients.

«This is the first demonstration, to our knowledge, of successful quantitative predictions of the individual behavioral state from gene expression patterns in the brain of a mammal,» says Miyakawa.

A further 25 days in medium containing FGF2 and Noggin mediated the derivation and expansion of RPCs which had a similar global gene expression pattern to cells of the embryonic day 14 (E14) mouse retina.

By examining gene expression patterns, the new study found that parrot brains are structured differently than the brains of songbirds and hummingbirds, which also exhibit vocal learning.

They compared the resulting gene expression patterns in all the parrot brains with neural tracing experiments in budgerigars.

Analysis of liver gene expression patterns of the exposed rats found that the endocrine disruptors induced developmental reprogramming of the animals» epigenomes.

For Helicobacter pylori, a pathogenic bacterium that colonizes over 40 percent of the world population and is associated with gastric cancer, the team discovered that epigenetic heterogeneity can quickly emerge as a single cell divides, and different subpopulations with distinct methylation patterns have distinct gene expressions patterns.

Results show that one night of partial sleep deprivation activates gene expression patterns in peripheral blood mononuclear cells (PBMCs) consistent with increasing accumulation of damage that initiates cell cycle arrest and increases susceptibility to senescence.

«Gene analysis adds layers to understanding how our livers function: Tracking gene expression patterns for 20,000 gene in 1,500 cells revealed a mosaic of activities.»

Gene expression patterns point to new autism candidate genes that could also play roles in schizophrenia and bipolar disorder

In this project, the researchers used single cell technology to explore gene expression patterns in healthy and diseased hearts.

Their microbial exposures varied and gene expression patterns varied, but the parts of the genome that were open at each location in the gut remained consistent, Crawford said.

She's now scrutinizing gene expression patterns and other features of banked tumors for more clues.

We identified species - specific gene expression patterns indicating that changes in protein and gene expression have been particularly pronounced in the human brain.

We're now able to recapitulate that process and begin to study things like gene expression patterns and the distinct steps involved in this process.»

Kaur et al. [68] examined selected gene expression patterns in rat retinas from 3 to 14 days after hypoxia.

The «gene expression in tooth database» contains gene expression patterns of different cells and compartments of the tooth at distinct time points, as determined by in situ hybridization or by immunostaining.

Now researchers at the Salk Institute for Biological Studies have identified an essential cellular pathway in zebrafish that paves the way for limb regeneration by unlocking gene expression patterns last seen during embryonic development.

Fluid forces can cause cultured cardiac cells to alter gene expression patterns and rearrange their cytoskeleton.

IMPRINTOME STOP SIGNS: Gene expression patterns for 42 imprinted genes (y axis) vary across diverse tissues (x axis), with redder boxes denoting stronger skewing towards just one allele.

In collaboration with Yi Xing from UCLA, the team catalogued and analyzed how gene expression patterns in skin cells differed among the Esrp knockouts and found hundreds of significant changes.

This paper was selected for the Trainee Paper Spotlight because it emphasizes the importance of miRNA on population specific gene expression patterns.