Sentences with phrase «gene expression patterns in»

Already, we see great benefit from the reciprocal links between gene expression patterns in BGEM with the Mutant Mouse Regional Resource Centers and with GENSAT.

Besides information gathered to answer specific experimental questions, as determined by the interests of individual partners [35]--[41], the collective data offered the opportunity to search for coordinated gene expression patterns in a systematic exploration of the mouse ES transcriptome under a battery of different experimental settings, thus minimizing possible site - specific artifacts.

Makarevitch I, Harris C * (2010) Aneuploidy causes tissue - specific qualitative changes in global gene expression patterns in maize.

The Core provides equipment and services to determine gene expression patterns in mouse and human tissues.

Effects of ploidy and sex - locus genotype on gene expression patterns in the fire ant Solenopsis invicta.

Identifying gene expression patterns in relation to the compound could facilitate the selection of the most appropriate patient cohorts for clinical development.

This resource will be valuable for researchers studying gene expression patterns in coral reproductive cycles and evolution of the genus Acropora.

We are also equipped with advanced imaging system technology offering non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in relevant models using non-virulent mycobacteria tagged with bioluminescense genes.

Gene expression patterns in normal adult or the developing retina have been reported for mouse [18 — 23], aged and normal adult human [24 — 26], canine [27], and rabbit [28].

Kaur et al. [68] examined selected gene expression patterns in rat retinas from 3 to 14 days after hypoxia.

Gene expression patterns in the hippocampus samples were examined using DNA microarrays that measured the expression levels of over 30,000 genes (transcripts) per sample.

The researchers found that gene expression patterns in the hippocampus accurately predicted whether the mice were in a state of high or low locomotor activity.

Now, researchers at the Institute for Comprehensive Medical Science, Fujita Health University, and ATR Computational Neuroscience Laboratories in Japan have succeeded in predicting states of mood - change - like behavior by studying the gene expression patterns in the brain in a bipolar disorder mouse model.

«Gene expression patterns in the hippocampus may retain information about past locomotor activity.»

«This is the first demonstration, to our knowledge, of successful quantitative predictions of the individual behavioral state from gene expression patterns in the brain of a mammal,» says Miyakawa.

They examined the effect of meditation on gene expression patterns in both novice and regular meditators.

In this project, the researchers used single cell technology to explore gene expression patterns in healthy and diseased hearts.

When Bordenstein and Brucker compared gene expression patterns in normal and microbe - free offspring, they found significant changes in many of the genes involved in the immune response (Science, doi.org/m87).

Results show that one night of partial sleep deprivation activates gene expression patterns in peripheral blood mononuclear cells (PBMCs) consistent with increasing accumulation of damage that initiates cell cycle arrest and increases susceptibility to senescence.

Consequently, the unique gene expression patterns in every tissue dictate its structure and function.

In collaboration with Yi Xing from UCLA, the team catalogued and analyzed how gene expression patterns in skin cells differed among the Esrp knockouts and found hundreds of significant changes.

In a related paper published online today in Nature Biotechnology, Konrad Hochedlinger of the Harvard Stem Cell Institute in Cambridge and his colleagues compared the gene expression patterns in mouse iPS cells derived from white blood cells, muscle precursor cells, immune system cells called B cells, and fibroblasts taken from tail tips.

They compared the resulting gene expression patterns in all the parrot brains with neural tracing experiments in budgerigars.

Recent advances in the understanding of cancer have led to more personalized therapies, such as drugs that target particular proteins and tests that analyze gene expression patterns in tumors to predict a patient's response to therapy.

Humans have an ortholog of the murine Nrk gene, and considering that the gene expression pattern in breast tumor in Nrk mutant mice was similar to that in human luminal B breast cancer, the findings of this study may lead to further understanding of the mechanisms of human breast cancer suppression and to advances in its diagnosis and therapy.

These features were related to a modified gene expression pattern in adult male testes, showing an altered gene expression in genes involved in DNA repair and apoptosis that was confirmed by TUNEL assay.

A recent study showed exposure flu viruses among women during pregnancy provoke a similar gene expression pattern in the fetus as that seen in autistic children.

Not exact matches

In the clearest possible case, the ANT - OAR cell would differ from a zygote on all of the parameters noted above: The ANT - OAR cell would have a pattern of gene expression that is clearly distinct from a zygote; it would generate a homogeneous population of cells rather than multiple cell types; it would undergo simple cleavage divisions and not produce any multicellular structures.

The shared patterns of gene expression in the limbs and phallus are generated in part by a common set of noncoding DNA, also called «elements» or «enhancers,» which act to control gene expression in both of these structures, argues a study published October 1 in Developmental Cell.

Even more striking, the gene - expression pattern in the hippocampi of THC - treated aged mice was radically different from that of untreated elderly mice.

Scans showed remodeled DNA methylation patterns in the low - fat group, which changed gene expression associated with fat metabolism and inflammation in the liver; there was less fat accumulation and inflammation in the liver.

PATTERNS of gene expression in a woman's blood may give a clue as to whether she is likely to get pregnant using IVF.

«By observing neuronal gene expression in these distinct pathways during development, we detected common patterns, as if an underlying genetic language was bringing them together.»

However, microgravity can reduce cell growth, alter gene expression and change the pattern of root growth — all aspects which critically affect plant cultivation in space.

The patterns of gene expression matched and often preceded physiological changes in the intestine, the researchers wrote.

By day 34 of development, however, the pattern of gene expression was much more similar to control cows derived from artificial insemination, suggesting that these surviving clones were able to implant in the uterus and begin to form a placenta.

Traditional strain - selection techniques are supplemented with strain screening, which can involve examining gene - expression patterns through PCR or understanding global gene expression in relation to environmental factors using gene chips.

To identify genes involved in the patterning of adult structures, Gal4 - UAS (upstream activating site) technology was used to visualize patterns of gene expression directly in living flies.

The trick is to run the tape of evolution over again: to intervene in the development of a chicken embryo, for instance, to reverse evolution, rolling back the clock to manifest earlier patterns of gene expression.

Research published this month in Nature Neuroscience identified a surprisingly small set of molecular patterns that dominate gene expression in the human brain and appear to be common to all individuals, providing key insights into the core of the genetic code that makes our brains distinctly human.

Although a bad outcome was possible without the gene expression pattern, patients with the genetic signature were found to survive for less time than those who didn't have it, they wrote in the 9 December online edition of Nature Genetics.

«We discovered that beta blockers largely reverse the pathological pattern of gene expression observed in heart failure,» said Faculty of Science Professor John McDermott, who led the research, along with York U collaborators Professor Gary Sweeney and Professor Jorg Grigull.

Indeed, the group found that the affected gene, named left - right dynein (lrd), comes on in the «node» — a key source of patterning signals — just before the appearance in the mouse embryo of the first known left - right asymmetries, the left - sided expression of two genes called nodal and lefty.

They found that gene expression is different at 209 sites in chronically lonely people and that many of those changes fit a pattern of elevated immune activation, inflammation, and depressed response to infection.

These areas in parrots also show some special patterns of gene expression, which the scientists speculate might explain why some parrots are also able to learn to dance to music.

Sure enough, salmon with a certain pattern of gene expression in their gill tissue were 13.5 times more likely to die than those that didn't carry the «you've not got long to live» signature, as co-author and University of British Columbia (U.B.C.) fish physiologist Tony Farrell puts it.

Another version, the CTC - iChip, rapidly isolates CTCs in a way that does not rely on preidentified tumor antigens, allowing capture of cells with gene expression patterns that may be missed by the antibodies used in the HBCTC - Chip.

SIX3 and a related gene, SIX2, with a similar pattern of expression in human beta cells, encode proteins known as transcription factors that control the expression of many other genes in the cell.

Researchers have videotaped cultures in which embryos develop but found no visual pattern that hints at which cells are about to sprout, and staining for certain patterns of gene expression has been inconclusive.

It isn't clear exactly why the differences fade, Hochedlinger says, but it may be that the expression of embryonic genes is strengthened as the cells grow in culture, gradually overwriting the cells» old gene - expression patterns.