To better illustrate
gene expression profiles in mouse ES cells, we have organized the results in an interactive database with a number of features and tools.
Challenges
with gene expression profiling in a biotech setting and recent technical advances with NanoString PlexSet ™ - Originally aired JAN 24, 2018
Although many common genes were expressed in the three tissues, cluster analysis based on transcript levels revealed
distinct gene expression profiles of the d - 18 EET (Fig. 2C and SI Appendix, Fig.
Broeks et al
analyzed gene expression profile data to query whether differences in molecular subtype exist between sporadic breast cancers and breast cancers associated 1with RT exposure.
Melanocytes respond by altering gene transcription, and these changes in
gene expression profiles result in easily quantifiable phenotypes such as modified pigment production (a hallmark of melanocyte differentiation state) and changes in morphological cell properties.
They identified
gene expression profiles typical of different types of neurons, newborn neural progenitors and radial glia, as well as molecular markers differentiating oRGs and vRGs, which allowed the researchers to isolate these cells for further study.
Dr. Loftus's research has gone on to detail how SOX10 and its downstream target gene MITF coordinately regulate
gene expression profiles associated with melanocyte differentiation.
In a recent attempt, oncologist Todd Golub of the Dana - Farber Cancer Institute in Boston, Massachusetts, and his colleagues
collected gene expression profiles, taken from public databases, from 76 tumors.
By combining
salivary gene expression profiles, postconceptional age and sex, this predictive model not only assessed the probability of feeding success, but also, and most importantly, highlighted specific developmental pathways that were likely contributing to feeding immaturity.
To carry out their census, the study team relied heavily on single - cell RNA sequencing (scRNA - seq), a suite of genomic techniques capable of identifying
specific gene expression profiles within individual cells.
With DriverMap ™
Targeted Gene Expression Profiling Service, Cellecta offers a quantitative, multiplexed approach that allows simultaneous profiling of all human protein - coding genes in one reaction, thereby providing a reliable, accurate transcriptome profile with ultra-high sensitivity.
The research group has analysed the transcriptome of these species, in other words, the set of all mRNA molecules that
reflect gene expression profiles of the genome.
During his undergraduate training at the University of California, Los Angeles, he was drawn to clinical research, leading to a Ph.D. at Boston University where he combined clinical research and computers to establish new algorithms and approaches for studying disease pathways by
compiling gene expression profiles using Expressed Sequence Tags.
Whole - blood
RNA gene expression profiles were analyzed in RS - III (recruitment, 2006 - 2008 [n = 762]-RRB- and SHIP - TREND (recruitment, 2008 - 2012 [n = 991]-RRB-, and fecal H pylori antigen in SHIP - TREND (n = 961).
«There was a sense that the test was scarce or difficult to obtain, which heightened patients» desire for it and led them to
perceive gene expression profiling tests as the deciding factor in their chemotherapy decisions, over and above other clinical tests and indicators,» she said.
Oncologists
welcome gene expression profiling tests as an added tool in deciding whether women with early - stage breast cancer should have chemotherapy, a new study has found.
We
performed gene expression profiling of DC - committed progenitor cells and now aim at understanding the molecular mechanisms underlying DC - lineage differentiation on a candidate - based approach.
PHOTO: Harbour LaboratoryUsing very small amounts of tumor tissue collected by a needle biopsy, doctors can
conduct gene expression profile testing to determine the likelihood that an ocular melanoma tumor will spread beyond the eye.
Lo M, Tsao MS, Hedley D, Ling
V. Gene expression profiling of adenosine triphosphate - binding cassette transporters in response to K - ras activation and hypoxia in human pancreatic cancer cell cultures.
B - E)
Differential gene expression profiles of molecules involved in extracellular matrix production in Terc - / - BMSCs — notable genetic molecules were related with ECM collagens, basement membrane constituents, ECM proteases, ECM protease inhibitors and other molecules associated with ECM.
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Research Highlight
FUNCTIONAL GENOMICS
Linda Koch
Cancer genetics
• Functional genomics
• Gene expression profiling
• Gene...