Sirtuin activators, notably resveratrol (which activates both SIRT1 and PGC - 1α, and improves the functioning of the mitochondria) 23 24 have been shown to inhibit
gene expression profiles associated with muscle aging and age - related cardiac dysfunction in mice and may extend lifespan.25 26
Dr. Loftus's research has gone on to detail how SOX10 and its downstream target gene MITF coordinately regulate
gene expression profiles associated with melanocyte differentiation.
Not exact matches
Lead author Johan den Boon,
associate scientist with the Morgridge Institute for Research at the University of Wisconsin - Madison, says the research team used
gene expression profiling on 128 specimens from the Study to Understand Cervical Cancer Early Endpoints and Determinants, or SUCCEED.
Hormone ‐ replacement therapy influences
gene expression profiles and is
associated with breast ‐ cancer prognosis: a cohort study
We use extensive genomic and
gene -
expression profiling techniques to identify molecules and molecular pathways that mediate the dynamic changes observed in vitro, and which are
associated with different clinical outcomes in melanoma patients.
HDAC inhibitors and decitabine are highly synergistic and
associated with unique
gene -
expression and epigenetic
profiles in models of DLBCL
As one example of his contribution, Wahl's team reported the first identification, isolation and characterization of mouse fetal mammary stem cells and their
associated gene expression profiles.
Radiation -
associated breast tumors display a distinct
gene expression profile.
Muscle biopsies from the study showed «a remarkable reversal of the
expression profile of 179
genes associated with age and exercise training... Genes that were down - regulated with age were correspondingly up - regulated with exercise, while genes that were up - regulated with age, were down - regulated with exercise.&r
genes associated with age and exercise training...
Genes that were down - regulated with age were correspondingly up - regulated with exercise, while genes that were up - regulated with age, were down - regulated with exercise.&r
Genes that were down - regulated with age were correspondingly up - regulated with exercise, while
genes that were up - regulated with age, were down - regulated with exercise.&r
genes that were up - regulated with age, were down - regulated with exercise.»
The altered microbiota was
associated with changes in colonic short - chain fatty acid (SCFA) concentrations, colonic - tissue
gene expression (Gsta2 and Ela1), and host physiology (serum metabolite
profiles and colonic goblet cell numbers).