Sentences with phrase «gene expression profiles in»

An international team of scientists sequenced the genome of the California two - spot octopus — the first cephalopod ever to be fully sequenced — and mapped gene expression profiles in 12 different tissues.

Using the two link buttons on the left, it is possible to further study the gene list of a particular «wave» in the context of publicly available databases, or view the gene expression profiles in ExpressView.

To better illustrate gene expression profiles in mouse ES cells, we have organized the results in an interactive database with a number of features and tools.

Previous studies have linked gene expression profiles in bCSCs with a clinical outcome [1, 2], and in this study the authors have extended this out to demonstrate that a DNA methylation profile may promote these changes, and furthermore, that this profile can be effectively used to predict prognosis, and potentially aid the therapeutic decision making.

«We observed widespread changes in gene expression profiles in more than 4000 genes following nanoparticle exposure, something that had not been reported on previously,» say first authors Jake Carrow and Lauren Cross.

Development of a gene expression assay in non-human primates: We will develop a novel sensitive assay for the characterisation of vaccination - related gene expression profiles in NHPs, using an approach that is fully harmonised with the systems biology platform.

Using single cell RNA sequencing analysis, the Cairns lab profiled cells individually, establishing the gene expression profile in human sperm stem cells.

Farkas et al. [29] and Ivanov et al. [30] reported on gene expression profiling in purified populations of rat retinal ganglion cells.

By looking at the gene expression profile in single cells, the researchers were able to identify previously unknown transient states that typified the progression from precursor to more - specialized cells.

Effects of warm ischemic time on gene expression profiling in colorectal cancer tissues and normal mucosa.

However, wildtype and PPARα − / − mice clustered together, even after cold exposure, indicating a similar overall gene expression profile in the two genotypes.

On the publication of the article «Gene Expression Profiling in the Hibernating Primate, Cheirogaleus Medius», with the participation of José Luis Villanueva - Cañas (Josefa Gonzalez's group):

In this study, we have shown the gene expression profile in human adipocytes treated with anthocyanins (cyanidin 3 - glucoside; C3G or cyanidin; Cy).

In this study, we have shown for the first time the gene expression profile in isolated rat adipocytes treated with anthocyanins (cyanidin 3 - glucoside; C3G or cyanidin; Cy).

Gene expression profiling in persons with multiple chemical sensitivity before and after a controlled n - butanol exposure session

Not exact matches

Scientists at Southern Methodist University, led by Professor and Chair of Biological Sciences Santosh D'Mello, have used RNA - Seq to conduct transcriptome profiling of gene expression changes in dying neurons.

They discovered that in the young, more immune cells called monocytes were recruited to the lungs, and that the gene expression profiles of these cells had more inflammatory features, causing greater inflammation and more severe lung injury.

In a recent attempt, oncologist Todd Golub of the Dana - Farber Cancer Institute in Boston, Massachusetts, and his colleagues collected gene expression profiles, taken from public databases, from 76 tumorIn a recent attempt, oncologist Todd Golub of the Dana - Farber Cancer Institute in Boston, Massachusetts, and his colleagues collected gene expression profiles, taken from public databases, from 76 tumorin Boston, Massachusetts, and his colleagues collected gene expression profiles, taken from public databases, from 76 tumors.

In a paper published in Nature Methods, postdoctoral fellows Naomi Habib, Inbal Avraham - Davidi, and Anindita Basu; core institute members Feng Zhang and Aviv Regev; and their colleagues reveal DroNc - Seq, a single - cell expression profiling technique that merges sNuc - Seq with microfluidics, allowing massively parallel measurement of gene expression in structurally - complicated tissueIn a paper published in Nature Methods, postdoctoral fellows Naomi Habib, Inbal Avraham - Davidi, and Anindita Basu; core institute members Feng Zhang and Aviv Regev; and their colleagues reveal DroNc - Seq, a single - cell expression profiling technique that merges sNuc - Seq with microfluidics, allowing massively parallel measurement of gene expression in structurally - complicated tissuein Nature Methods, postdoctoral fellows Naomi Habib, Inbal Avraham - Davidi, and Anindita Basu; core institute members Feng Zhang and Aviv Regev; and their colleagues reveal DroNc - Seq, a single - cell expression profiling technique that merges sNuc - Seq with microfluidics, allowing massively parallel measurement of gene expression in structurally - complicated tissuein structurally - complicated tissues.

«Signaling pathways and gene expression profiles are very different in cells that grow in 2D and 3D cultures,» says Oksana Sirenko, a research scientist at Molecular Devices in Sunnyvale, California.

A new effort by DOD, NCI, and the Department of Veterans Affairs will profile gene and protein expression in thousands of individuals» tumors.

In 2006 Potti's team published several papers in high - profile journals reporting that certain gene expression signatures predicted a patient's response to chemotherapIn 2006 Potti's team published several papers in high - profile journals reporting that certain gene expression signatures predicted a patient's response to chemotherapin high - profile journals reporting that certain gene expression signatures predicted a patient's response to chemotherapy.

The significance of the new model, according to Grange, is that «it enables us to now have a biological understanding of the patterns, the co-expression profiles, seen in the Allen Gene Expression Atlas of the Mouse Brain.»

If the gene expression profile of a neuronal type is measured, then the model predicts where in the brain that type of neuron can be found.»

Researchers from BUSM and the University of Cyprus compared the markers on the surface of the cancer cells to gene expression profile of breast tumors deposited by researchers in international public databases and found that a molecule named IL13RA2 (IL13R alpha2) was abundant in metastatic or late - stage BLBC.

In profiling gene expression in the 128 specimens, the study posed the question: What other genes might be behaving like p1In profiling gene expression in the 128 specimens, the study posed the question: What other genes might be behaving like p1in the 128 specimens, the study posed the question: What other genes might be behaving like p16?

In vitro experiments and high - throughput RNA sequencing revealed that CTCF deletion profoundly altered the B lymphocyte transcriptional program, shifting cells from a gene expression profile typical of the germinal center to one more similar to that seen in plasma cellIn vitro experiments and high - throughput RNA sequencing revealed that CTCF deletion profoundly altered the B lymphocyte transcriptional program, shifting cells from a gene expression profile typical of the germinal center to one more similar to that seen in plasma cellin plasma cells.

«These findings raise the possibility that by determining the gene expression profile of a patient's tumor, physicians may be able to identify aggressive disease at the outset of diagnosis and start treatment earlier,» said Sungyong You, PhD, an instructor in the Cedars - Sinai Department of Surgery and the first author of the study.

The team used gene expression profiling and found that canine B - cell lymphoma expression profiles were similar in many ways to human B - cell lymphoma, thus paving the way for future studies, including therapeutic clinical trials in dogs and humans.

Whole - blood RNA gene expression profiles were analyzed in RS - III (recruitment, 2006 - 2008 [n = 762]-RRB- and SHIP - TREND (recruitment, 2008 - 2012 [n = 991]-RRB-, and fecal H pylori antigen in SHIP - TREND (n = 961).

Ma and colleagues first discovered that mitochondria was involved in SMA when they analyzed gene expression profiles of motor neurons from SMA and control mice.

The MD Anderson team also is looking at gene expression, mutations and immune profiling to identify potential differences in melanoma in obese and non-obese patients and developing preclinical models.

«Because the primary Small Intestine Chip recapitulates the physical microenvironment that cells experience inside the human body, such as fluid flow and cyclic peristalsis - like stretching motions, it exhibits a genome - wide gene expression profile that comes closer to its in vivo counterpart than that of the same intestinal cells grown as 3D organoids,» said first - author Magdalena Kasendra, Ph.D., a former Postdoctoral Fellow on Ingber's team and now Principal Scientist at Emulate, Inc. in Boston.

«Our present study shows examination of the gene expression profiles at the very early age of initial clinical detection reveals both strong evidence of early biological processes in ASD and abnormal signals with the potential to serve as an early, practical biomarker of risk for the disorder in general pediatric settings.»

The team found deep conservation of certain processes that likely reflects similar underlying regulatory processes between mouse and man, but there were also significant differences in gene expression during kidney development, as well as in the timing, scale, organization, and molecular profile of key cell types and cell structures.

They compared space - flown endothelial cells to endothelial cells cultured under normal gravity, looking for differences in gene expression and / or in the profile of secreted proteins.

This single cell transcriptome analysis followed by computational analyses enabled the team to identify the gene expression profiles of cells in the process of changing from ES cells to 2CLCs.

Profiling the expression patterns of host genes revealed that the insect significantly increases the abundance of B vitamin transporters and activation enzymes when reared in the absence of its gut microbes.

The case for direct interaction was bolstered by similarities between gene expression profiles of plants with various deficiencies in photoreceptors and COP1.

Ontario was the first province in Canada to fund gene expression profiling tests.

Gene sequencing provides an organism's genome sequence, but gene expression profiling reveals where and when in the body certain genes are actGene sequencing provides an organism's genome sequence, but gene expression profiling reveals where and when in the body certain genes are actgene expression profiling reveals where and when in the body certain genes are active.

Oncologists welcome gene expression profiling tests as an added tool in deciding whether women with early - stage breast cancer should have chemotherapy, a new study has found.

To identify genes whose expression correlated with adiposity, we profiled gene expression in perigonadal adipose tissue from 24 mice in which adiposity varied due to sex, diet, and the obesity - related mutations agouti (Ay) and obese (Lepob).

Altered promoters in GC change the gene expression profile of GC cells and may confer its oncogenic properties, including cell movement and cancer signalling.

Kinetics study on markers of the immune system by gene expression profiling of an in vivo heated tumor.

Using quantitative RT - PCR we confirmed the expression profile of five genes (colony - stimulating factor 1 receptor [Csf1r], Cd68, Pex11a, Emr1, and Mcp1) in each of the 24 samples and found excellent agreement between the microarray and RT - PCR expression data (mean Pearson correlation coefficient = 0.91, microarray versus RT - PCR expression; Supplemental Table 3, http://www.jci.org/cgi/content/full/112/12/1796/DC1).

«Gene expression profiling allows us to identify drugs that are potentially useful when given in combination.

In these cases, drug exposure caused significant changes in tumor cells» gene expression profile but had no lasting physical effecIn these cases, drug exposure caused significant changes in tumor cells» gene expression profile but had no lasting physical effecin tumor cells» gene expression profile but had no lasting physical effect.

While expression levels of all marker genes remained almost unchanged in wild - type ACVR1 cultures compared with the empty viral vector, the expression profile induced by caACVR1 Q207D displayed evidence of advanced chondrogenic differentiation as shown by decreased levels of the early differentiation stage marker collagen type II together with enhanced expression of the later - stage markers Ihh and collagen type X. Indian hedgehog has been shown previously to be induced by BMP signaling transmitted via the ACVR1 receptor (9).

To detect novel changes in gene expression, we used a focused microarray platform to evaluate the expression profile of retinas from hypoxic animals compared to that in retinas isolated from control animals exposed to room air.