Sentences with phrase «gene expression profiling reveals»

Gene sequencing provides an organism's genome sequence, but gene expression profiling reveals where and when in the body certain genes are active.

Their gene expression profile revealed striking up - regulation of peroxisome proliferator - activated receptor gamma coactivator 1alpha (an up - regulator of mitochondrial biogenesis not normally expressed in white fat), increased uncoupling proteins - 1 and -2, and down - regulation of lipogenic enzymes.

Not exact matches

Citation: Lemay DG, Ballard OA, Hughes MA, Morrow AL, Horseman ND, Nommsen - Rivers LA (2013) RNA Sequencing of the Human Milk Fat Layer Transcriptome Reveals Distinct Gene Expression Profiles at Three Stages of Lactation.

In a paper published in Nature Methods, postdoctoral fellows Naomi Habib, Inbal Avraham - Davidi, and Anindita Basu; core institute members Feng Zhang and Aviv Regev; and their colleagues reveal DroNc - Seq, a single - cell expression profiling technique that merges sNuc - Seq with microfluidics, allowing massively parallel measurement of gene expression in structurally - complicated tissues.

Indeed using genome - wide transcriptional profiling, the researchers revealed that expression of clipped H3.3 silences genes that regulate the division and duplication of a cell.

In vitro experiments and high - throughput RNA sequencing revealed that CTCF deletion profoundly altered the B lymphocyte transcriptional program, shifting cells from a gene expression profile typical of the germinal center to one more similar to that seen in plasma cells.

«Our present study shows examination of the gene expression profiles at the very early age of initial clinical detection reveals both strong evidence of early biological processes in ASD and abnormal signals with the potential to serve as an early, practical biomarker of risk for the disorder in general pediatric settings.»

Profiling the expression patterns of host genes revealed that the insect significantly increases the abundance of B vitamin transporters and activation enzymes when reared in the absence of its gut microbes.

A detailed comparison of gene expression signatures between ETP ALL tumors and and normal human hematopoietic progenitor cells revealed a somewhat surprising finding: ETP - ALL expression patterns were less consistent with early T - cell precursors, as might have been expected, but more similar to the expression profile of normal hematopoietic stem cells and granulocyte macrophage precursors.

Calcification rate measurements and gene expression analysis by microarray RNA transcriptional profiling at two time - points (midday and night - time) revealed several genes common within mammalian gene regulatory networks.

Comparison of mRNA and protein expression revealed distinct expression profiles for many genes and underscores the importance of multi-omic analysis in single cells.

Proteomic analysis to profile protein abundance resulted in the identification and relative quantification for 912 proteins with two or more unique peptides and 86 proteins with significant abundance changes after treatment with the neurotoxins, while microarray analyses to profile gene expression revealed 181 genes with significant changes in mRNA after treatment.

MicroRNA expression profile and functional analysis reveal that miR - 382 is a critical novel gene of alcohol addiction.

Mapping the expression profiles of all genes one cell at a time revealed unexpected heterogeneity in the stem cell - derived lung cells, and the research team at the CReM used this information to improve the airway cells engineered in the lab.

Unbiased clustering analysis of P (+) neurons revealed four different classes, each with distinct cell surface receptor gene expression profiles.

Although many common genes were expressed in the three tissues, cluster analysis based on transcript levels revealed distinct gene expression profiles of the d - 18 EET (Fig. 2C and SI Appendix, Fig.