Sentences with phrase «gene expression regulation»

The main research focus of the single molecule group is the study of molecular motors, the role of force in regulating biological systems, and the molecular mechanisms of gene expression regulation.

Our computational biology research programme focuses on gene expression regulation and the mechanisms by which it can be disrupted in human diseases such as cancer.

He is interested in gene expression regulation, computational biology, and data visualization.

Karolina Jastrezbowska (Tomancak, MPG)-- «Evolution of gene expression regulation during embryonic development of Drosophila species» (2010)

We have a longstanding interest in understanding gene expression regulation, and in our wetlab at the Sanger Institute use mouse T helper cells as a model of cell differentiation.

MicroRNAs are small, non-coding RNAs that do not translate into proteins, yet have a profound impact on gene expression regulation.

There already has been great effort to elucidate the mechanisms of gene expression regulation, but it will be important to continue research to fully realize the potential of these epigenetic therapies and their applications in clinical settings.

One is straightforward — during development, cells are assuming their identities and need precise control over protein production, so cells lacking a gene expression regulation mechanism are bound to have defects, particularly in the case of specialized cells like neurons.

Using this «Ribotag» approach tissue - specific changes under DR have been measured in muscle, fat, gut, heart, neurons, germline and malpighian tubules, showing a highly tissue specific response upon DR.. We are developing mechanistic models of gene expression regulation and conducting comprehensive bioinformatics analyses on UTRs, promoters and the coding sequences of various elements of differentially regulated genes.

PROJECT INFORMATION: RNA fate determination is at the center of gene expression regulation, influencing the stability, localization, and translation efficiency of mRNAs.

During my thesis project I performed RNAseq and differential expression analysis for investigating the gene expression regulation under two different oxidative stress conditions.

While these model organisms can provide interesting insight, drosphilia and humans have drastically different metabolisms and gene expression regulation.