Sentences with phrase «gene expression show»

It is important to distinguish lineage specific gene expression shown here, which occurs at a high level and with a degree of specificity in the different population compartments, to the low level of genome wide transcription observed in ES cells by others [22], or with transcript initiation at many loci noted previously in ES cells [23].

Not exact matches

There's better communication,» she told Inc.com in an interview, citing science that shows meditation changes the brain, immune system, and even gene expression.

Results showed that BPA exposure permanently affected the uterus by decreasing regulation of gene expression.

In subsequent analyses, striking losses in gene expression were observed in genomic regions that had become increasingly methylated with age, whereas regions that had become less methylated showed increases in gene expression.

This study built on previous research from the Sundrud lab, which showed that when TH17 cells entered the intestine in human tissue samples, they increased the expression of a gene called MDR1.

The male offspring of mothers fed the high - fat diet showed altered gene expression in the hippocampus which persisted through adulthood.

This image shows the metabolic expression of a gene identified by scientists from EPFL in Lausanne and ETH Zürich as being a key player in the development of type 2 diabetes.

Scans showed remodeled DNA methylation patterns in the low - fat group, which changed gene expression associated with fat metabolism and inflammation in the liver; there was less fat accumulation and inflammation in the liver.

A team of scientists led by the University of Birmingham has shown how a common mRNA modification, N6 - methyladenosine (m6A), regulates gene expression to determine the sex of fruit flies.

The clones also appeared to have an effect on the gene expression of the pregnant cows themselves; on day 34, some uterus tissue showed grossly different gene expression, which could affect the placenta.

The Epstein - Barr virus, which infects some 90 % of Americans, may cause changes in gene expression that dramatically increase a person's chance of getting lupus and six other autoimmune disorders, a new study by Harley, now a rheumatologist at the Cincinnati Children's Hospital Medical Center in Ohio, and colleagues shows.

This work shows the power of using the tools of computational genomics to analyze gene expression patterns for the purpose of elucidating the evolution of behavior.

According to the researchers, this is the first study to link the extreme and rapid eating - induced changes of the Burmese python's intestines directly to changes in gene expression, and also the first to show how quickly gene expression changed.

This study, published in the journal Microarrays, shows that lack of SOST in the bone microenvironment promotes the expression of many genes associated with cell migration and / or invasion, including long non-coding RNA MALAT1 in prostate cancer, suggesting that SOST has an inhibitory effect on prostate cancer invasion.

These areas in parrots also show some special patterns of gene expression, which the scientists speculate might explain why some parrots are also able to learn to dance to music.

Previous work from Dekker and colleagues had shown that points of interaction along the chromosome influence gene expression and are the reason why different cell types are organized differently in three dimensions.

The second duplication appears in supplemental figure S6, where a scatterplot purporting to show gene expression similarities between the cell lines was used twice.

Dr. Seibold and his colleagues showed that gene expression in the nasal passages overlaps 90 % with genes expressed in the lungs.

Knocking down expression with RNA interference showed that 30 % of newly arisen genes are essential for viability.

Gene expression profiling was performed on blood samples taken from 70 RA patients: 50 of whom had shown a good response to the anti-TNF biologic treatment adalimumab, 20 of whom had shown no response to this drug.

The results showed that, when applied, a long - term inhibition of Rho - kinase signaling increased the expressions of chondrocyte - specific genes and differentiation markers in human chondrosarcoma 2/8 cells.

Evaluation of the levels of gene expression in these blood samples showed a distinct change in RA patients who had responded to treatment.

PR - 2B sfRNA showed sequence - dependent binding to and prevention of tripartite motif 25 (TRIM25) deubiquitylation, which is critical for sustained and amplified retinoic acid — inducible gene 1 (RIG - I)-- induced type I interferon expression.

«The 20 - year difference in expression of the gene abnormality shows the devastating consequences of recent environmental factors, such as eating high - glycaemic foods and a lack of exercise,» Froguel says.

«Margery's experiments showed that the NS1 protein can alter expression of Hedgehog target genes on its own, without other viral proteins,» said Bier, professor and newly named holder of the Tata Chancellor's Endowed Professorship in Cell and Developmental Biology.

Mesenchymal glioma stem cells show significantly higher radiation resistance and high expression of DNA - repair genes;

An analysis of gene expression of the known fungal partner in the two species showed no differences.

«This miRNA suppresses expression of HMGA1, a gene that was shown in previous studies to be associated with prostate cancer progression and recurrence,» says Leung.

The Epstein - Barr virus (EBV), which infects some 90 % of Americans, may cause changes in gene expression that dramatically increase a person's chance of getting lupus and six other autoimmune disorders, a new study by Harley and colleagues shows.

The study shows that even small, tissue - specific changes in the expression of genes can have noticeable morphological effects.

Their results showed that both forms of RP had clear differences in gene expression compared to normal retinas.

Three decades of research have shown that loneliness can affect levels of stress hormones, immune function, and even gene expression, while human interaction increases levels of oxytocin, a bonding hormone that reduces blood pressure and cortisol levels.

This magic spot was later identified as ppGpp and shown to influence the expression of over 500 genes in response to stress.

The researchers in the RNA Biochemistry Group at Freie Universität Berlin were able to show that mice use this time - of - the - day - dependent change in body temperature to adapt gene expression to clock - dependent requirements.

Kingsley's research has shown that these adaptive changes are often driven by changes in the regulatory regions that surround and control gene expression, rather than within the coding regions of the genes themselves.

Bone marrow mesenchymal stem cells and bone cells from the skulls of Cbf - beta - deficient mice showed increased expression of adipocyte genes.

Further studies discovered that the BRAF protein could turn on many itch genes, and they showed similar changes of gene expression in mice with chronic itch induced by dry skin and in mice with allergic contact dermatitis, two of the skin conditions that frequently cause people to scratch incessantly.

We even did gene - expression studies in flies showing that genes in their brains change their level of activity in waking and in sleep.

Results show that one night of partial sleep deprivation activates gene expression patterns in peripheral blood mononuclear cells (PBMCs) consistent with increasing accumulation of damage that initiates cell cycle arrest and increases susceptibility to senescence.

«We have shown that the synthesis of nitric oxide (NO), known to regulate gut motility functions and NRF2, a transcriptional factor known to regulate several antioxidant genes, mediated Phase II protein expression have been altered in colon specimens of polybacterialinfected ApoE - / - mice,» said Miriam Walker.

Our work shows an exciting new way that eRNAs produce these different patterns of gene expression.

However, the study showed the one area of the brain with the most human - specific gene expression is the striatum, a region most commonly associated with movement.

The loss of the mark leads to inappropriate gene expression as shown by the re-expression of genes usually only seen late in embryo development.»

Light can be used as an accurate method to control gene expression, shows groundbreaking optogenetics study by University of Colorado, Duke University and University of Helsinki researchers.

Now researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg show robust evidence that not only the inherited DNA itself but also the inherited epigenetic instructions contribute in regulating gene expression in the offspring.

The variant lies near a gene called telomerase RNA component, or TERC, and earlier studies in animals have shown that low TERC expression is associated with shorter telomeres, and faster biological aging.

«Gut's microbial community shown to influence host gene expression.»

The study, led by Michael Greenberg, Ph.D., Chairman of the Department of Neurobiology at Harvard University, shows that MECP2 dampens the expression of long genes.

A team of researchers from three departments at New Jersey Medical School, led by Michael Mathews and Hartmut Hanauske - Abel, previously showed that Ciclopirox, commonly used by dermatologists and gynecologists to treat fungal infections, inhibits the expression of HIV genes in culture.

Plants perform these regulations mainly by regulating nuclear gene expression and multiple intracellular signaling pathways have been shown to play a role in the genomic response of plants to stress, but the processes are not well understood.