For custom gene expression projects the Genomics Core has a platform that uses sets of human and mouse custom arrays whose probe content is aimed at
gene expression studies in the areas of cancer, immunology and other complex diseases.
Based on
gene expression studies of fat tissue conducted at the USDA HNRCA, the Tufts University researchers initiated studies of the role of FAT10 in adipose tissue and metabolism.
Global
gene expression studies found that the LPA - treated mice shared many similar molecular markers as those found in humans with schizophrenia.
Gene expression studies led researchers to find RNA fragments in the bees from viruses that are transmitted by Varroa mites, a long - time foe of honeybees that beekeepers were treating with a variety of pesticides.
To begin to explore the cellular mechanisms that might be responsible for this response, histological analysis revealed less severe disruption of spermatogenesis and
gene expression studies suggested that an interplay of ATP - binding cassette (ABC) efflux transporters and solute carrier (SLC) influx transporters in the testicular cells might be involved.
In 2017, it will be joined by Anipath, a platform devoted to the histological analysis of small animal models including phenotyping, diagnosis of morbidity cause, in
situ gene expression studies.
We use large -
scale gene expression studies and phenotypic analyses in defined sets of mouse strains (so - called genetic reference populations) as well as sophisticated biomathematical tools to learn about how high - dimensional gene - gene interactions respond to the activity - dependent stimulus and affect the stem cells and developing new neurons.
Genes putatively related to calcification (e.g. calcium and inorganic carbon transport, H + transport and carbonic anhydrases) have been identified
via gene expression studies comparing calcifying and non-calcifying E. huxleyi cells [25 — 29], or in short - term experiments where calcification was regulated by limitation of ions needed for calcification (i.e. Ca2 +, HCO3 − / CO32 − [26,30,31]-RRB-.
«Single - nucleus RNA sequencing, droplet by droplet: DroNc - Seq, technology that merges single - nucleus RNA sequencing with microfluidics, brings new scale to
gene expression studies in complex tissues.»
Multiple real - time PCR platforms are available
for gene expression studies, including Agilent Mx3005p and Mx3000p instruments, a Roche LightCycler 480 II with interchangeable 96 - and 384 - well modules, and a Roche LightCycler 1536 with an associated Innovadyne Screenmaker 96 +8 liquid handling workstation.
The team is now working on other conditional knockout and
gene expression studies of Esrp1 and Esrp2's roles in the face, lungs, gut, kidney, and other organs.
Bloch's colleagues at the National Institute of Environmental Health Sciences tested the oils in
gene expression studies on lab - grown human breast cancer cells and found that they could mimic estrogens, the primary female sex hormones, and inhibit androgens, the primary male sex hormones.
In
gene expression studies, investigators find those genes that are most commonly expressed in either healthy or diseased tissue.
«Atlas of developing human brain launched by researchers:
Gene expression study may provide insights into autism, other neurodevelopmental disorders.»
One reason is that researchers recently realized that tumor biopsies preserved in paraffin, the most common method, can be used for sequencing and
gene expression studies.
DroNc - Seq — a technology that merges single - nucleus RNA sequencing with microfluidics — brings new scale to
gene expression studies in complex tissues.
Bioinformatics has now firmly established itself as a discipline in molecular medicine, and encompasses a wide range of subject areas from structural biology, genomics to
gene expression studies and personalised medicine.
Hematopoietic stem cells from various sources (bone marrow, cord blood and peripheral blood) are isolated and characterized by phenotyping and
gene expression studies.
Molecular Characterization of Mn - superoxide Dismutase and
Gene Expression Studies in Dietary Restricted Brachionus plicatilis Rotifers