Sentences with phrase «gene families for»

Fisher's exact test as implemented in R66 was run to test for enrichment or depletion of numbers of gene families for each molecular function category in the novel versus ancestral gene sets.

Not exact matches

The other, a former White House aide to President Obama, tested positive for the BRCA2 gene mutation that has led to breast cancer in her family for generations — and is taking aggressive steps to avoid the same fate.

The Craig Scholarship was established in 2016 by the Craig family and is named for Jeanette W. and Eugene «Gene» L. Craig.

Last, had I known that alcoholism is a disease worse than cancer, and that it ran through the family genes thus any baby born had a strong chance of becoming one... well, that seals the deal but, I bet the parents who also fell for religiosity, not knowing it was an enclave for pedophiles... talk about regrets from hell.

I'm diabetic due to my family's genes, and Christians work to stunt stem cell research — all for religious reasons.

Altruism begins with kin, who share genes, so that if I die for my family or clan, my genes survive in their offspring.

The worry is that «the technical ability to disaggregate and recombine genetic, gestational and rearing connections and to control the genes of offspring may... undermine essential protections for offspring, couples, family and society.»

«My family has been dedicated to providing the best meats, poultry and produce for 55 years,» President and CEO Gene Baratta says.

If somewhere in the human genome there is a gene for a sweet tooth, then my family has it!

Never cared for sex and the mortality in my family genes is actually pretty high, though!

Jeter's family was on the field before the Yankees - Tigers game for a pregame ceremony and Jalen Jeter showed off his cap tipping genes.

You become a family not because you share the same genes, but because you share love for each other.»

Both kids have had their work selected for the town art show and I am glad the art gene has found a way to my family.

Some mothers aren't able to breast feed for medical reasons, so «wishing a gene pool would die off» because a family has to rely on formula vs. breast milk is absurd and to dignify that comment with more time - well it would probably be inappropriate.

But your husband's family history has absolutely no bearing on your own children, except maybe for the future possibility that you might have twin grandchildren — if you have a daughter who inherits the hyperovulation gene.

Luckily for me, a few hours of sleep, a supportive family, and lucky genes were all it took to feel normal again.

The researchers also described the full gene repertoires for known drug target families.

«My team at Nationwide Children's has worked with commitment and dedication to develop a therapy that may subsequently be shown through future clinical trials to potentially alter the course of this unforgiving condition and provide a therapeutic option for the families and infants with SMA1,» says Jerry Mendell, MD, principal investigator in the Center for Gene Therapy at Nationwide Children's.

Mutations in the SOD1 gene account for about 12 percent of ALS cases that run in families.

«We found that interbreeding with archaic humans — the Neanderthals and Denisovans — has influenced the genetic diversity in present - day genomes at three innate immunity genes belonging to the human Toll - like - receptor family,» says Janet Kelso of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.

«For 20 years we've been looking for the gene and mutation behind my family's neuropathy, but we never found the variant,» he saFor 20 years we've been looking for the gene and mutation behind my family's neuropathy, but we never found the variant,» he safor the gene and mutation behind my family's neuropathy, but we never found the variant,» he says.

Since genes for the T - cell receptor beta chain were previously shown to be on mouse chromosome 6, all three of the Ig - like multigene families expressed and rearranged in T cells are located on different chromosomes, just as are the B - cell multigene families for the Ig heavy chain, and the Ig kappa and lambda light chains.

«Fibroblast growth factor receptor inhibitors are new therapies being developed in clinical trials for patients whose cancer cells have genetic alterations in this family of genes,» says Roychowdhury, a member of the OSUCCC — James Translational Therapeutics Program.

He interviews cardiac researchers at the National Institutes of Health to explore whether he, too, carries the gene for his father's disease; he meets a family who has the gene, all of whom live with the knowledge of their eventual undoing.

In 2004 the Nobel Prize in Physiology or Medicine went to Linda B. Buck and Richard Axel for their research showing that there is a huge family of genes that encode proteins called olfactory receptors.

In living people, a rare mutation that causes members of a family to produce half the usual amount of FOXP2 protein also triggers severe speech defects, notes Simon Fisher, director of the Max Planck Institute for Psycholinguistics in Nijmegen, the Netherlands, who discovered the gene.

To build a family tree for the orchids, the scientists sequenced genes in the green structures, called chloroplasts, in which plants transform solar energy into sugar.

Affected family members, the group found, had inherited one or two defective copies of ZIC3, a previously unknown gene that appears to code for a transcription factor — a protein that switches other genes on or off.

Brin writes on his blog that the genome scan of his saliva from 23andMe told him he has a mutation on the LRRK2 gene, a variation called G2019S, which ups the risk for Parkinson's in some families.

Most cases of familial hypolipidemia are linked to other gene mutations that cause liver and digestive problems, but in members of this American family with the condition, Musunuru found mutations in the gene for ANGPTL3, and no associated health problems.

«Mutations responsible for cleft palate and related birth defects identified: Study of Amish and Saudi Arabian families finds mutations in HYAL2 gene that impact development.»

A geneticist in his 20s with a family history of Huntington's disease — a fatal condition with a simple genetic basis and symptoms which typically manifest in middle age — decides to test himself for the disease gene.

He and his colleagues gathered genetic data from 156 frog species and combined this with earlier information about two genes from 145 different frogs, for a total of 301 distinct frog species from all 55 families of frogs.

This placed them in a new family, meaning it was beneficial to care for their own children at first (because they were more genetically related to them than they were to the rest of the family) and to care for their grandchildren later (when more of their genes made it into the family group).

Deafness has long been known to run in families, and while genes for about 60 syndromes that have deafness as one of multiple symptoms have been mapped, only last month did scientists locate the first of the estimated 100 genes that can cause hearing loss alone.

Forty percent of the participants were positive for the APOe4 gene and 74 percent had a parental family history of Alzheimer's, both of which are known to increase the risk for developing Alzheimer's.

In 1993, Brunner discovered a predisposition to violence in a single Dutch family carrying a mutation in the gene which makes monoamine oxidase A (MAOA), another enzyme vital for regulating neurotransmitter levels in the brain.

After examining eight such families from the Sichuan province of southeastern China, the duo discovered that in two of the families, the parents (who could hear) had one mutated copy of the gene for myosin VIIA.

From the family tree they worked out an «inbreeding coefficient» for each marriage — a figure reflecting the proportion of inherited genes in the children that would be identical from both parents.

They found genes for five new receptors, all of which belong to a known family of proteins called formyl peptide receptors (FPRs).

The system relies on admixture — a genetic principle that argues that when a family migrates across a geographic barrier into a new location, they start mating with the locals; new traits start blending into their gene pool, and this genetic diversity provides a ruler for gauging the distance from home.

Until now, de novo genetic mutations, alterations in a gene found for the first time in one family member, were believed to be mainly the result of new mutations in the sperm or eggs (germline) of one of the parents and passed on to their child.

Julian Isla, Executive Director of DSF - EU, stated: «One of the most important things for patients with genetic disorders and their families is to be able to give a name to the gene causing their disease.

Women with a family history of two or more immediate family members (mother, sister, daughter) with breast or ovarian cancer or with a positive genetic test for mutations in the BRCA1 or BRCA2 genes may be advised to consider having both breasts removed, because they are at high risk of a new cancer developing in the other breast.

Although there is no direct test yet, women in some families with large numbers of cases can be tested for known genetic markers that are inherited alongside the gene.

NIPD for single gene disorders in a fetus is diagnostic, as it targets specific genetic changes present in a high risk family.

Mental illness appears to be partly heritable (bipolar disorder, for one, runs in families), yet no one has discovered a gene for the disease.

However, by investigating the genes of two rose cultivars selected for certain desirable characteristics, Jean - Louis Magnard and colleagues discovered that the flowers» fragrances were facilitated by a completely unexpected family of enzymes.

«For example, we have studied two more families with similar pathological characteristics, but with no mutation in the ATP4a gene.

Family - based genome analysis enabled us to narrow the candidate genes for both of these Mendelian disorders to only four.