Sentences with phrase «gene families involved»

GENE families involved in respiration and photosynthesis arose in a short evolutionary burst that began nearly a billion years before Earth's atmosphere became rich in oxygen.

The proteins of ISGF3, the IFN - alpha induced transcriptional activator, define a gene family involved in signal transdution.

Not exact matches

By providing a woman's family history of these cancers, including the ages they were diagnosed, the programs calculate a probability that the patient carries a harmful mutation in BRCA1 or BRCA2 (genes involved in controlling malignant cell growth).

The protein studied in the mold is part of a larger family of proteins also found in humans and involved in many essential biological processes including gene regulation and fatty acid metabolism.

«The most intriguing of these genes is FGFRL1, which has a cluster of amino acid substitutions unique to giraffe that are located in the part of the protein that binds fibroblast growth factors — a family of regulators involved in regulating many processes including embryo development,» Cavener said.

And he expects that fraction to rise considerably when the team continues the research on more families and with more sensitive DNA probes — work that will also help pin down the genes involved.

It is particularly useful when clinicians want to identify an illness or gene mutation involving a single patient or the patient and two or three other family members, which is the most common clinical situation for undiagnosed diseases.

The researchers found that over 25 percent of index patients with normal results from commercial testing of BRCA1 and BRCA2, but with families severely affected by breast cancer, could be resolved by sequencing all genes known to be involved in breast cancer.

«Scientists sequence genomes of microscopic worms beneficial to agriculture: Study identifies gene families in five nematodes that are likely to be involved in parasitism.»

By also examining this genetic region in two other families with similar disorders, the researchers were able to pinpoint a mutation in a specific gene, NT5E, which is involved in breaking down calcification in the arteries.

«We have also found a number of gene families that seem to be involved in the parasitism of insects by worms and we are excited to continue studying these in future experiments.»

A year ago we started thinking, why don't we select a single family with an interesting disease and see whether studying a smaller group of related individuals makes it possible to identify the genes involved in that disease.

They also identify factors that may be involved in duck host immune response to avian virus infection, including the avian and mammalian - defensin gene families.

Although it shows no sign of the whole - genome triplication identified in Solanaceae species such as tomato, the genome includes several species - specific gene family expansions, among them N - methyltransferases (NMTs) involved in caffeine production, defense - related genes, and alkaloid and flavonoid enzymes involved in secondary compound synthesis.

Genetic sequencing of three families of pitcher plants from the Americas, Asia and Australia shows that they all repurposed genes normally involved in the stress response to make the insect - killing fluids in their pitcher - shaped leaves (Nature, doi.org/bzb5).

Known as Slit and Trk - like family member 1 (SLITRK1), it was related to a group of genes known to be involved in neuronal growth, guidance, and branching.

This approach, which relies on a few large families, can produce misleading results for a disorder such as ADHD which may involve several genes, unlike single - gene disorders such as cystic fibrosis or Huntington's disease.

Another interesting local network structure is centered around CLU, a gene shown to be involved in AD based on genome - wide association studies, with genes in the integrin family, involved in cell adhesion, clustered around CLU.

Knowing that the ADGRE2 gene is involved, at least in the three study families, gives scientists a new tool as they continue to look at why people have allergies — an area that is not well understood.

Also, genes that code for receptor tyrosine kinases, a family of receptors on the surface of cells, may rearrange to form multiple distinct gene fusion partners, as evidenced in an article by Kulkarni, et al, on a translational study involving a patient who developed a BRAF fusion following treatment with a BRAF inhibitor1.

Whereas IRF - 9 functions as an adaptor for tethering the different STAT dimers to ISRE, other members of IRF family have also been shown to be involved in the regulation of ISRE - containing genes.

The researchers discovered striking differences from other invertebrates, including widespread genomic rearrangements and a dramatic expansion of a family of genes involved in neuronal development that was once thought to be unique to vertebrates.

The gene expression viewer has proven to be an ideal tool for comparing gene family members, genes whose products participate in ligand — receptor interactions, and genes involved in signal transduction pathways.

Transcriptome Profiling of Petal Abscission Zone and Functional Analysis of an Aux / IAA Family Gene RhIAA16 Involved in Petal Shedding in Rose

HDACs are a family of enzymes which, amongst other things, influence access to DNA and are involved in whether specific genes, such as tumor suppressing genes, are expressed or not.

The recent recognition that de novo lipogenesis might have relevance for lipid homeostasis in skeletal muscle stems from the realization that Sterol regulatory element binding protein - 1c (SREBP - 1c), a member of the family of transcription factors that regulate the expression of genes involved in lipid storage in liver and adipose tissue, is also present in skeletal muscle at a level close to that observed in the liver, 41,42... [M] ost fascinating are the very recent demonstrations that glucose alone (in the absence of insulin) can stimulate de novo lipogenesis in skeletal muscle cells....

In rodents and humans, defects in the same T - box gene family that I mentioned regarding missing or defective spinal component (ref) is often involved.

His wife, Gene Jones, is actively involved in the construction of Cowboys Stadium, the Cowboys Art Program, and Jones Family Charities.

A gene family that is involved in development, the zinc - finger transcription factors, is also highly expanded in octopuses.

STAT6 is part of the STAT family of transcription factors, its phosphorylation in response to cytokines and growth factors activates the transcription of many genes involved in the immune system such as interleukin 4 (IL - 4).