Although it shows no sign of the whole - genome triplication identified in Solanaceae species such as tomato, the genome includes several species - specific
gene family expansions, among them N - methyltransferases (NMTs) involved in caffeine production, defense - related genes, and alkaloid and flavonoid enzymes involved in secondary compound synthesis.
Not exact matches
These adaptations include the massive and rapid
expansion of
gene families that produce venom toxins, providing the snake with a highly toxic protein mixture required to overcome a variety of different prey and also circumvent any resistance to venom that may have developed in such prey.
Armed with the both the king cobra and Burmese python genome the team was able to show that, despite previous hypotheses that venom
genes evolve «early» in the lineage leading to snakes, venom
gene families do not duplicate early, in fact the study shows that the rapid and extensive
expansion of functionally important venom toxin
families is restricted to the venomous «advanced» snake lineage.
Candida species that often cause disease usually have
expansions in these
gene families, so given that C. krusei is rarely pathogenic, this finding makes sense.
Genome comparison revealed that the great
expansion of several
gene families in the deep - sea mussel may be related to its adaptation to the deep sea.
«The exciting thing here is the
expansion of a
gene family associated with expression in specific neurons,» says Evan Eichler, a geneticist at the University of Washington, Seattle.
In particular, the improved subtelomeres have enabled us to dissect the pir
gene family further, and have revealed a novel and unexpected
expansion of methyltransferase
genes.
The genome encodes a large number of novel receptor kinases and contains
expansions of a variety of
gene families, including those associated with virulence.
Comparisons of whole - genome sequences reveal the
expansion of
gene family clusters to be an important mode of genome evolution.
In P. cynomolgi, we observed an
expansion of the STP1
family (51
genes).
Although we have seen that sponges and eumetazoans share many common pathways related to morphogenesis and cell - type specification, there are notable genomic differences, including different microRNA assemblages46, lineage - specific domains and domain architectures, and the differential
expansions of
gene families.
The most notable
expansion was in the protocadherins, a
family of
genes that regulate neuronal development and short - range interactions between neurons.
The researchers discovered striking differences from other invertebrates, including widespread genomic rearrangements and a dramatic
expansion of a
family of
genes involved in neuronal development that was once thought to be unique to vertebrates.
Instead, the evolution of the octopus genome was likely driven by the
expansion of a few specific
gene families, widespread genome shuffling and the appearance of novel
genes.