Sentences with phrase «gene for hip»

Previously, a possibility of the existence of a major gene for hip dysplasia has been reported in the German Shepherd Dog and the Labrador Retriever (Leighton, 1997).

Nevertheless, other results also obtained in this study suggested the conclusion that there is a major gene for hip dysplasia.

Likewise, if both parents of any breed carry the gene for hip dysplasia (abnormal hip socket formation), whether or not they actually have dysplasia themselves, their puppies now carry a double recessive and are far more likely to have or develop this crippling disease.

Just because a dog has the gene for hip dysplasia however, does not mean he will be affected: the severity of the disease will be directly influenced by the dog's diet and other environmental factors such as exercise level or body condition — or so the theory goes.

Genes for hip dysplasia are believed to be «masked» or hidden in some generations, making the elimination of the disease from breeding stock even more difficult.

In evaluating the hips of dogs genetically predisposed to dysplasia, certain factors could make the hips in the leg - extended radiographs appear worse, compared to another dog with presumably the same genes for hip joint construction, such as a littermate or a dog with otherwise near - identical genotype yet reared differently.

To prevent hip dysplasia in pets, especially in those with the genes for hip dysplasia in their families, do not overfeed your pet while he or she is growing.

Not exact matches

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Once gesicles have been made, they can be harvested, concentrated, and applied to hiPS cells, where the active Cas9 / sgRNA complex is released and transported to the nucleus for efficient gene editing.

Workflow for targeted knockout of CD81, an endogenous gene in hiPS cells, using the Cellartis iPSC CRISPR / Cas9 Gesicle and Single - Cell Cloning System.

However, hiPS cell - derived hepatocytes are only useful as an in vitro model system and for gene editing applications if they recapitulate critical hepatocyte functions.

Other genes relevant for regulating blood cholesterol levels are well - expressed in enhanced hiPS - HEP cells, e.g., apolipoprotein B (a VLDL), apolipoprotein A1 (an HDL), PCSK9, sterol regulatory element - binding proteins 1 and 2 (SREBP - 1 and -2), and lipoprotein lipase (LPL), which hydrolyzes triglycerides in lipoproteins into free fatty acids and glycerol.

(«Thanks, mom, for the Celiac gene and the propensity for thyroid issues...» «The hips and thighs, they're thanks to you too, right?»)

More than one gene is responsible for the deformity of the hip joints.

You can't blame Max for not knowing, polygenetic traits were unknown at the time; but in selecting Klodo, he selected for some very undesirable gene combinations that favored joint problems like hip dysplasia and cruciate ligament ruptures.

There are also some breed specific issues you will need to research if you want a certain pastoral type: for example those related to the Blue Merle gene in Border Collies, or hip problems in German Shepherds.

Dr. George Lust of Cornell talks of «eliminating genes responsible for abnormal hip joint conformation».

The presence of hip or elbow dysplasia is a clear indication that an animal is genetically predisposed for the disease; thus, there is a possibility that the dog will contribute some genes that predispose its offspring for developing the disease.

If there is a recessive gene for an inherited disease, such as hip dysplasia, a pup born of related dogs has an increased chance of having that particular problem.

Scientists have yet to uncover the specific gene in dogs that code for the canine hip dysplastic trait.

If you want your dog to be able to reproduce among the registry, your dog will need to have a working title like protection dog or seeing eye dog, as well as certain measurement minimums for their hips and elbows before it's allowed to contribute to the gene pool.

People focusing on breeding dogs with longer coats will also breed some genes responsible for hip dysplasia in a given dog, and if the other partner shows similar signs, the future generation surely will display a beautiful coat, but the offspring's body structure will also be poor.

However, Tina discovered if x-rays were taken of not only dogs that were intended for breeding, but of all litter mates born, those genotypes or recessive genes would reveal themselves allowing her to only breed those dogs who did not carry the gene causing hip dysplasia.

They watch for known breed problems and try their hardest to keep things like hip dysplasia and bad temperments out of the gene pool.

It may be that different heritable conditions are influenced by the same genes to some degree (for example hip and elbow dysplasia in some breeds).

With breadth of normalcy in the littermates of breeding dogs, and even of parents of breeding dogs, you are more efficiently selecting for a preponderance of those «normal - hip» genes.

It also means dogs with normal hips on x-ray may carry the genes for the disease and you may have several generations of normal dogs before the problem «suddenly» appears in your line.

Ensure your Red Nose Pitbull puppy's parents have had their hips scored (to ensure they are healthy) and ask if either parent has been gene tested for myelopathy.

By selecting for individual components of the hip radiograph, you may be more directly selecting for specific «normal - hip» genes.

The relatively high estimates of the frequencies of the unfavourable recessive alleles in each breed, especially for hip dysplasia, suggest that it would be possible to gain considerable genetic progress by selection against a major gene.

for article An indication of major genes affecting hip and elbow dysplasia in four Finnish dog populations.

The existence of a major gene was considered likely for hip dysplasia in all the breeds and for elbow dysplasia in one breed.

Estimated nonparametric marginal densities for polygenic (σ2u) and major gene (σ2w) variance for hip dysplasia (HD) in the German Shepherd, as an example of all breeds.

For instance, Lawler et al. [38] report hip dysplasia in a red fox suggesting ancient hip dysplasia liability genes.

If, as Dr. Olsson has said, osteochondrosis is the description of a general disorder in which HD is one manifestation, and elbow problems are others, then perhaps by selecting for normal hips, our better American breeders were unwittingly and unintentionally selecting dogs with fewer genes for osteochondrosis of any sort, including in elbows.