Sentences with phrase «gene in the human version»

The team sequenced the gene that codes for the NaV1.7 channel in mole rats, and compared it with SCN9A — a key gene in the human version of the channel.

Not exact matches

But when Cherr and his colleagues finally got around recently to checking out the protein in humans, they got a big surprise: About a quarter of men don't make it properly because they have a mutant version of the relevant gene.

The less adept mice, Rubin's team found, carry extra copies of a previously known human gene called DYRK; a mutated version of an almost identical gene in fruit flies, called minibrain, causes neurological defects.

When we took the mouse version of this gene — the same gene we find in the human — and put it in the fly and tweaked it, we induced fly eye tissue.

Shatz got a hint when she looked up ailments associated with mutations in genes coding for the human version of MHCI.

First they smuggled the gene aboard a disabled version of the adeno - associated virus, which thrives in the guts of rats and humans.

All land vertebrates carry a version of the FOXP2 gene, so some of the Oxford researchers then teamed up with colleagues from the Max Planck Institute for Evolutionary Anthropology in Germany to analyze what is unique about the variant in humans and to track how the gene had evolved in our ancestors.

In 2002 a student in Christiano's lab was studying the Human Genome Project database and noticed an unnamed region where Christiano had predicted the human version of the lanceolate gene would residIn 2002 a student in Christiano's lab was studying the Human Genome Project database and noticed an unnamed region where Christiano had predicted the human version of the lanceolate gene would residin Christiano's lab was studying the Human Genome Project database and noticed an unnamed region where Christiano had predicted the human version of the lanceolate gene would reHuman Genome Project database and noticed an unnamed region where Christiano had predicted the human version of the lanceolate gene would rehuman version of the lanceolate gene would reside.

To try to determine how those changes influenced the gene's function, that group put the human version of the gene in mice.

To prevent this decline in Area X, White's research team used methods similar to human gene therapy to insert a version of FoxP2 in male zebra finches.

In both humans and birds, cells process this gene in a way that produces both a full - length protein and a shorter version of the proteiIn both humans and birds, cells process this gene in a way that produces both a full - length protein and a shorter version of the proteiin a way that produces both a full - length protein and a shorter version of the protein.

When transplanted into human cells in the laboratory, the mammoth TRPV3 gene produced a protein that is less responsive to heat than an ancestral elephant version of the gene.

Scientists then looked at the human version of the gene, and found that the gene was mutated in people suffering from Native American myopathy.

On the other hand, in no case did Africans and Neanderthals share similar versions of a gene, to the exclusion of other humans.

Earlier versions of these «base editors,» which target typos related to the other half of disease - causing genetic spelling errors, have already been used to alter genes in plants, fish, mice and even human embryos.

Then for HARE5, the most active enhancer in an area of the brain called the cortex, they made minigenes containing either the chimp or human version of the enhancer linked to a «reporter» gene that caused the developing mouse embryo to turn blue wherever the enhancer turned the gene on.

The human version of the FOXP2 (short for fork - head box P2) differs from that of the chimp (the closest living relative of humans) in two places along the genetic code, causing differences in two amino acids in the protein coded by the gene.

It also contains some of the most variable human genes: hundreds of versions — or alleles — exist of each gene in the population, allowing our bodies to react to a huge number of disease - causing agents and adapt to new ones.

And researchers at Stanford University School of Medicine report in Genome Research that they linked the evolution of a gene in the old platypus to a mutated version in humans responsible for moving the testes outside of the body and into an external pouch, or scrotum.

Taking advantage of these «simplified» versions of melanoma, the researchers identified a dozen of new genes that are likely to play key roles in the initiation and / or progression of human melanoma.

In humans, Galatzer - Levy found that different versions of the fkbp5 gene were able to predict specific differences in extinction learning related to PTSD symptoms such as reliving or re-experiencing the traumatic event; avoiding reminders of the event; and, in particular, hyperarousal, or the inability to sleep or concentratIn humans, Galatzer - Levy found that different versions of the fkbp5 gene were able to predict specific differences in extinction learning related to PTSD symptoms such as reliving or re-experiencing the traumatic event; avoiding reminders of the event; and, in particular, hyperarousal, or the inability to sleep or concentratin extinction learning related to PTSD symptoms such as reliving or re-experiencing the traumatic event; avoiding reminders of the event; and, in particular, hyperarousal, or the inability to sleep or concentratin particular, hyperarousal, or the inability to sleep or concentrate.

So far, scientists have found that different populations of living humans have inherited the Neandertal version of genes that cause diabetes, lupus, and Crohn's disease; alter immune function; and affect the function of the protein keratin in skin, nails, and hair.

«Our conclusions make sense, especially in light of the work of other researchers who have shown that the human version of the FDNC5 gene has a deleterious mutation at the beginning,» Erickson said.

Might Neanderthals have benefited from gaining modern human DNA, for example, in their version of the FOXP2 gene?

«To hone in on functional conservation, we focused on Cindr, the fly's version of the human NS gene, CD2AP.

To wit, years after the Jans» report on atonal, the role of the gene's mammalian versions in human sight and hearing came to light.

A collaborative group of international researchers has now studied the human version of the ASIC1a gene, ACCN2, and report their findings in the current issue of Biological Psychiatry.

In mouse models in which the endogenous Smn1 gene has been knocked out and human versions of SMN2 have been swapped in, the Isis therapy — a so - called «antisense oligonucleotide» — delivered to the mouse central nervous system (CNS) increased the expression of full - length SMN protein in motor neurons, improved muscle strength in behavioral tests and extended the rodents» median lifespan from 16 days to 26 daysIn mouse models in which the endogenous Smn1 gene has been knocked out and human versions of SMN2 have been swapped in, the Isis therapy — a so - called «antisense oligonucleotide» — delivered to the mouse central nervous system (CNS) increased the expression of full - length SMN protein in motor neurons, improved muscle strength in behavioral tests and extended the rodents» median lifespan from 16 days to 26 daysin which the endogenous Smn1 gene has been knocked out and human versions of SMN2 have been swapped in, the Isis therapy — a so - called «antisense oligonucleotide» — delivered to the mouse central nervous system (CNS) increased the expression of full - length SMN protein in motor neurons, improved muscle strength in behavioral tests and extended the rodents» median lifespan from 16 days to 26 daysin, the Isis therapy — a so - called «antisense oligonucleotide» — delivered to the mouse central nervous system (CNS) increased the expression of full - length SMN protein in motor neurons, improved muscle strength in behavioral tests and extended the rodents» median lifespan from 16 days to 26 daysin motor neurons, improved muscle strength in behavioral tests and extended the rodents» median lifespan from 16 days to 26 daysin behavioral tests and extended the rodents» median lifespan from 16 days to 26 days3.

But, after researchers at Oregon Health and Science University managed to change the mutated version of the MYBPC3 gene to the unmutated version in a viable human embryo last month, the predictable bioethical debate was reignited, and terms such as «Designer Babies» got thrown around a lot.

Only a year after he produced the first iPS cells from adult mouse skin cells, Yamanaka generated iPS cells from adult human skin cells, employing human versions of the same four genes that he had used in the mouse work.