Hurley said adaptation to salt is likely affecting Daphnia at the epigenetic level, a heritable change in
gene levels rather than genetic code.
Not exact matches
Now, new research suggests changes at the epigenetic
level — specifically alterations in proteins that affect
gene expression,
rather than genetic mutations — could be driving childhood ependymomas.
«The
genes which these miRNAs regulate also had increased
levels, indicating that these
gene expression, indicating that these
gene products were likely targeted for storage and for possible future use within the brain cell,
rather than for destruction.
England's theory is meant to underlie,
rather than replace, Darwin's theory of evolution by natural selection, which provides a powerful description of life at the
level of
genes and populations.
Homozygous lethality of the XPCS allele is likely due to reduced
levels of expression of this essential protein as a result of
gene targeting (Figure 1A)
rather than to the mutation itself.
Rather, HAR2 functions as an enhancer, a DNA sequence that works to increase or decrease the
level of a
gene's expression.8 An enhancer can be located thousands of base pairs away from the
gene it regulates.
Surprisingly, whether or not a
gene's expression was regulated by MeCP2 did not depend on its mCG content;
rather,
genes with high
levels of mCH tended to be most affected by alterations in MeCP2 expression.