Not exact matches
Here we present an experimental reannotation of the GENCODE intergenic lncRNA populations in matched human and mouse tissues that resulted in novel transcript models for 3,574 and 561
gene loci, respectively.
It is important to distinguish lineage specific
gene expression shown
here, which occurs at a high level and with a degree of specificity in the different population compartments, to the low level of genome wide transcription observed in ES cells by others [22], or with transcript initiation at many
loci noted previously in ES cells [23].
The population genomic analysis method applied
here identifies statistically significantly co-evolving
locus pairs, potentially arising from fitness selection interdependence reflecting underlying protein - protein interactions, or
genes whose product activities contribute to the same phenotype.