The recommendation is to check for interaction with other polymorphisms (see, for example the replicability of «novelty seeking», where interaction of at least three
gene loci made replication uncertain [122].
Not exact matches
At the bottom is an extra line that includes the shorthand names of the 13 «CODIS
loci,» the locations on a person's
genes that are read to
make a DNA profile.
That can
make it hard to
make subtle changes to a
gene — like introduce point mutations corresponding to natural variations linked with human disease — without taking a sledgehammer to the entire
gene locus.
Hanner and Rusche used chromatin immunoprecipitation assays to show that this chimeric protein did not
make it to the HMRa or HMRα
loci or to other repressed
genes.