Sentences with phrase «gene locus on»

Samples were then forwarded from the University of California, San Diego - Comparative Neuromuscular Laboratory to the University of Minnesota Canine Genetics Laboratory and they identified a gene locus on chromosome 36 as the probable affected locus on the affected dogs.

The human T cell receptor beta (TRB, previously known as TCRB) gene locus on chromosome 7 (7q34) includes 65 Vb (variable) gene segments, followed by two separate clusters of genes each containing a Db (diversity) gene, several Jb (joining) genes, and a Cb (constant) region spread over 685 kilobases.

Not exact matches

At the bottom is an extra line that includes the shorthand names of the 13 «CODIS loci,» the locations on a person's genes that are read to make a DNA profile.

The so - called SERPINB gene cluster on chromosome 18 was identified as a specific genetic risk locus for food allergies.

A locus is the position of a gene on a chromosome.

The locus most strongly associated with severe CCD was found on chromosome 34 — a region containing three serotonin receptor genes.

The second locus significantly correlated with severe CCD was on chromosome 11, the same chromosome that contains a gene thought to increase the risk of schizophrenia in humans.

In this study, researchers found that the Bt locus was delimited to a 442 - kb region on chromosome 5 that harbors 67 predicted genes.

The genomics era has had a profound impact on life science research, leading to significant developments such as the use of expression quantitative trait loci (eQTLs), which link polymorphisms in single genes to quantifiable changes in gene expression associated with specific diseases.

Engelhardt's group was responsible for mapping associations between genetic variants and gene expression levels on different chromosomes, a connection known as «trans - expression quantitative trait loci (trans - eQTLS).»

Analyzing the DNA of about 3,500 diagnosed people and nearly 11,000 without the disorder, researchers homed in on a genetic locus — a gene's location on a chromosome — that's involved in the body's metabolic processes and seems to be associated with the disorder.

Prof Bentzen from Dalhousie University said: «Although this study focused on MHC genes in vertebrates, the evolutionary dynamics described in it likely apply to other gene families, for example resistance genes and those which prevent self - fertilization in plants (self - incompatibility loci) that are caught up in their own evolutionary races.»

Continued research will focus on identifying the mutated gene's location within the locus.

It will be important in future studies to improve both gene and taxon sampling for primate species, to construct separate trees based on mitochondrial and nuclear loci, and to tease apart differences that arise from incomplete lineage sorting versus other types of discordance including introgression and sex - biased dispersal [75]--[77].

Effects of ploidy and sex - locus genotype on gene expression patterns in the fire ant Solenopsis invicta.

Recent genetic association studies identified variants in a locus on chromosome 15 (specifically, in the adjacent genes HERC2 and OCA2) that are major determinants of eye color, but the trait is influenced by interaction among at least ten different genes.

Single loci with major effects in fire ants: the effects of the complementary sex - determining locus and the green beard supergene on gene expression

Dr. Radislav Sedlacek and his team from the Institute of Molecular Genetics has recently published new paper on gene targeting of Rosa26 locus using TALENs.

Reykjavik, September 19th, 1999 — deCODE genetics, Inc. announced today that they have identified a locus on chromosome 2p13 that contains a gene that is linked to pre-eclampsia in women — a condition that is indicated in an estimated three to seven percent of...

However, they were not designed to delineate regions of the genome resisting introgression nor investigate the frequency and types of genes involved in genetic incompatibilities, because they were based on a relatively small number of loci (less than 50) and the sampling of the genome was non-random (e.g. overrepresentation of the X-chromosome or regions near centromeres).

Genetic studies using samples along the distribution range of both subspecies and based on a few dozen nuclear markers have revealed loci of relatively high divergence (0.3 — 1.2 %) between subspecies embedded in a genome otherwise characterized by low levels of differentiation and high levels of bidirectional gene flow [21], [24]--[26], likely facilitated by high effective population sizes, high dispersal, and a relatively short generation time [21], [24]--[26].

A number of Invivoscribe LymphoTrack Assays, formatted for use on both the Illumina MiSeq ® and Thermo Fisher Ion PGM ™ platforms, were designed to detect somatic gene rearrangements within the antigen receptor loci.

Within the essential immune loci of the major histocompatibility complex, we find HLA - B to be the most polymorphic gene on chromosome 6 and in the human genome.

«We now have a really good handle on at least five genes that anyone would be comfortable saying are asthma risk loci,» said Carole Ober, PhD, co-chair of the EVE Consortium, senior author of the study, and Blum - Riese Professor of human genetics and obstetrics / gynecology at the University of Chicago.

The Em variant of the MC1R gene at the extension (E / e) Locus results in the localized distribution of eumelanin (black pigment) on the muzzle of the dog which resembles a dark «mask» on dogs with lighter colored coats.

The most basic genetic scenario is where a gene on a specific locus determines each trait.

Genes have pairs of alleles (one from each parent) that are located at specific sites (loci) on a chromosome.

However, the overall degree of shedding for a dog is dependent on a combination genes and a better understanding of a dog's degree of shedding currently comes from knowledge of a dog's genotypes at both the SD locus and IC (Improper Coat / Furnishings) locus.

Robyn Comeau Most white spotting on dogs is determined by the genes on the S locus.

Doing a genetic test and subsequently eliminating an individual from the breeding population may not be the best strategy, as by targeting a particular allele at one genetic locus for removal from the gene pool of a particular breed, breeders may in fact increase allele frequency of genetic variants on alternative haplotypes at the same, or a different locus, that are recessively deleterious.

It is convenient to give an alphabetical nomenclature to them in the places (loci, plural of locus) on the chromosome where those genes are located.

In their work on compulsive blanket and flank sucking in Dobermanns, the authors identified a single locus with genome - wide significance within the gene Cadherin 2 (cdh2), a widely expressed gene involved in pre - and post-synaptic adhesion.

Genetic studies have focused attention on the area of DYX2 on chromosome 6p21.3 as several genes in this locus have been associated with reading disabilities as well as the gene areas DCDC2 and KIAA0319 appear to both contribute to reading and writing disabilities.

More importantly, however, it will be crucial to determine (1) how this functional locus interacts with the allelic expression imbalance markers downstream (and which the actual locus conferring allelic expression imbalance is, see in what follows)(2), what the relative contribution to a net effect on serotonin transporter gene expression is in vivo and (3) how (if at all) this translates into protein abundance and actual genetically determined differential functioning of the serotonergic synapse.