Sentences with phrase «gene polymorphisms affect»
Illmer, T., Schuler, U. S, Thiede, C., Schwarz, U. I., Kim, R. B, Gotthard S., Freund, D., Schakel, U., Ehninger, G. and Schaich, M. MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients.
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Moderate level fetal alcohol exposure and serotonin transporter gene promoter polymorphism affect neonatal temperament and limbic - hypothalamic - pituitary - adrenal axis regulation in monkeys.
Although the biological mechanisms through which this polymorphism could affect aging are not known, it is adjacent to two genes called CDKN2A and CDKN2B, which play an important role in cell cycle regulation.
«These findings suggest that GCLM polymorphisms [gene variants] that affect glutathione production also affect methylmercury retention,» she wrote to me in an e-mail, «and that GSTP1 may play a role in conjugating [chemically joining] methylmercury with glutathione.»
Studies of worms and fruit flies show that variations, or polymorphisms, in a single gene can affect how long these creatures live.
«Looking for reward in all the wrong places: dopamine receptor gene polymorphisms indirectly affect aggression through sensation - seeking.»
Genetic polymorphisms in the gene encoding cytochrome P450 (CYP) 4F2, a vitamin K oxidase, affect stable warfarin dose requirements and time to therapeutic INR.
Methods.: Dogs of various breeds, affected or unaffected with primary glaucoma, were genotyped for the Gly661Arg variant of ADAMTS10, as well as 7 other nonsynonymous single nucleotide polymorphisms (SNPs) in other genes in the beagle POAG locus that segregate with disease.
However, researchers at the University of California — Berkeley wanted to find out if there might a genetic component that could predict how couple interactions affect marital satisfaction.5 Specifically, the team decided to look at the 5 - HTTLPR polymorphism in the promoter region of the serotonin transporter gene.
In relation to the association of infant attachment with a promoter polymorphism of the serotonin transporter gene, we have mentioned that gene expression may be affected by variation in the DNA sequence of the regulatory region of the gene.
Specifically, we hypothesized that increased frequency of S allele carriers of the 5 - HTTLPR functional polymorphism within East Asia is due to culture — gene coevolution, whereby collectivistic cultural values serve an adaptive function, reducing the probability of environmental stress, a known catalyst of negative affect, thus leading to genetic selection of the S allele within collectivistic cultures.
More recently, a common variable number tandem repeat (VNTR) polymorphism lying 1.2 kb upstream of the transcription initiation site of MAOA has been shown to affect transcriptional activity of the gene in transfected cells.
Moderate level fetal alcohol exposure and serotonin transporter gene promoter polymorphism affect neonatal temperament and limbic - hypothalamic - pituitary - adrenal axis regulation in monkeys.