Sentences with phrase «gene product on»

Not exact matches

(RTTNews)- Today's Daily Dose brings you news about FDA panel's vote on Achaogen's Plazomicin; Karyopharm's public offering; Cellectis» progress in TALEN gene - edited product pipeline; Globus Medical's Q1 financial results; a federal Court's ruling, which has gone in favor of Progenics / Valeant, and...

Gene Zimon § Gene Zimon is the Founder and President of EDGE Advisors which assists early stage companies develop their product and go - to - market strategies, and advises institutional investors and other companies on investments in and acquisitions of new technologies.

Nusinersen and similar compounds being developed for spinal muscular atrophy focus on increasing or making more of the SMN gene product that gets converted into usable protein.

It is likely that previously uncharacterized gene products with intriguing effects on behavior will be discovered within these networks.

These include the ability to bring new, innovative products to the market; progress in oncology, such as the approval of Genentech's drug Avastin for breast cancer and advances in the use of gene therapy, despite some setbacks; continuing progress in research on stem cells; the emergence of treatments for previously untreated diseases; and solutions for food and fuel shortages, such as biocrops and biofuels.

For example, genetically engineered organisms used in the research laboratory to develop new chemical synthesis methods are not likely to require the same level of public dialogue as products that have more uncertainty associated with them, such as organisms with gene drives, which enhance organisms» ability to pass certain genetic traits on to their offspring.

Kingsley's team had no idea what the normal gene does, but a team at the University of Tokyo had recently identified the genetic defect behind a similar mouse disease — and determined that its protein product normally generates pyrophosphate on the outside of joint cells to keep the joints scale - free.

Tattersall explains how epigenetic effects on key genes cascade to produce radical morphological changes in an eye blink, and why our unusual thinking style, far from being the perfected product of long - term selective pressures, was bootstrapped out of existing abilities barely 100,000 years ago.

Monsanto's newest drought - tolerant product, Drought Guard, relies on a gene that creates a chaperone protein to coat a plant's RNA during stressful conditions and maintain the plant's normal cell functions, while Syngenta's hybrid contains novel drought - tolerant gene combinations.

As a result, patents on human gene products allowed in some European countries may be banned in others.

Requiring just nine simple gene edits, in naturally occurring organisms, and based on phosphite — a readily available industrial waste product; it is extremely cost and time effective.

«Industry giants like Google, Microsoft and Yahoo are spending tens of billions of dollars a year on acquiring smaller firms for market entrance, strategic intellectual property and talented employees, but face a real challenge identifying companies with the right products or technology in the vast startup universe,» said Gene Moo Lee, UTA assistant professor of Information Systems and Operations Management.

Kuruvilla's lab group — which has been studying the peripheral nervous system for years — found that abundance of a particular gene product in Down syndrome puts a brake on NGF's actions in fostering nerve development.

They do social science, health, philosophical, policy, or legal research on topics such as privacy, confidentiality, the psychological impact of genetic information, informed - consent issues in genomics research, commercialization of genetic products, genetically modified foods, behavioral genetics, gene testing, and gene therapy.

New gene - editing technologies such as CRISPR have sped the development of new crop varieties and animals, but products based on engineered organisms sometimes face a web of complex and overlapping regulations before they can reach the market.

Instead he found a genome - wide divide, with some genes churning out a staggering 300 percent more of their product, depending on whether they were in males or females.

The statements were carefully worded to support patents on «new gene - based health care products.»

«On the one hand, it says that we should regulate by the product, and not the process, but then goes on to admit that the newer GE techniques, such as gene editing and synthetic biology, will produce more diverse and complex traits in more crops that could raise new safety concerns, noting that even the newer gene editing techniques have off - target effects,» he saiOn the one hand, it says that we should regulate by the product, and not the process, but then goes on to admit that the newer GE techniques, such as gene editing and synthetic biology, will produce more diverse and complex traits in more crops that could raise new safety concerns, noting that even the newer gene editing techniques have off - target effects,» he saion to admit that the newer GE techniques, such as gene editing and synthetic biology, will produce more diverse and complex traits in more crops that could raise new safety concerns, noting that even the newer gene editing techniques have off - target effects,» he said.

Although there are currently no gene therapy products on the market in the U.S., recent studies in both Parkinson's disease and Leber congenital amaurosis, a rare form of blindness, have returned very promising results.

The lawsuit against Myriad Genetics and the University of Utah Research Foundation, which hold the patents on the genes, charged that the challenged patents are illegal and restrict both scientific research and patients» access to medical care, and that patents on human genes violate the First Amendment and patent law because genes are «products of nature.»

«Until recently, the process was thought to be continuous — once a gene is switched on, it stays on, churning out protein products at a steady pace like a garden hose.

His work centers on developing general, rational approaches to design precision medicines from genome sequences by targeting the RNA product of genes.

«Silencer» molecules, that control when a gene is turned on or off, are the products of the epigenome.

(The eukarya, thought to be descended from the archaea, rely on archaean - type genes to manage their DNA and to translate its genetic information into protein products.)

The location and sensitivity of hormone receptors is dictated by our genes, which naturally leads to the question, could the urge to cheat on our romantic partners be partly a product of our genes?

Under his leadership from 2009 - 2015, uniQure received the first - ever approval of a gene therapy product by the European Medicines Agency, built a pipeline of gene therapy products across several disease areas, obtained approximately $ 200M through its NASDAQ - listing and follow - on, and closed a multi-billion dollar collaboration in cardiovascular gene therapy.

A court case surrounding gene patents for high - risk forms of breast cancer puts two viewpoints of «products of nature» on the stand.

Transcriptional regulation information for a gene, including any predicted DNA binding site motifs (YeTFaSCo) for the gene's protein product, as well as any of its targets (genes it regulates) or regulators (genes that regulate it), based on experimental evidence.

It concentrates on analysis of gene function at all levels: the gene and its product, the cell and cellular interactions, embryonic tissues and the entire animal.

«With extensive experience at both large and small agriculture and industrial biotech companies, she is uniquely positioned to help Caribou capitalize on the potential opportunities for CRISPR - Cas gene editing to develop improved crops and bio-based products.»

The program will be packed with papers on biochromatography, downstream processing, QbD, monoclonal antibodies, plasmids, enzymes, vaccines, viral vectors for gene delivery, VLPs, and other biopharmaceuticals, chiral molecules, SFC, fine chemicals, peptides, proteins, oligonucleotides, APIs, natural products, batch, multi-column and continuous SMB processes, column technology and equipment, monoliths, new and improved stationary phases, membrane chromatography, regulatory aspects, and more!

A central biological concept that can explain how genes interact with environmental factors such as trauma on the molecular level is environmental epigenetics, the idea that we are not simply a product of our genes but also our experience.

Final confirmation would depend on studies of the effects of the mutation of the expression of gene products at the levels of RNA and protein.

The finding has implications for drug development, Moxon points out, because a drug targeted at a gene's product will not be of much use if the gene is frequently switched on and off.

For the first time, a food product created using CRISPR — a promising but controversial gene - editing technique — could be on track to be sold and eaten.

Studies on horizontal gene transfer and enzymemediated DNA rearrangements lead him to postulate a theory of molecular evolution according to which nature cares actively for the promotion of biological evolution by using products of specific evolution genes as well as several intrinsic non-genetic elements.

On the other hand, by means of high - throughput technologies, it is now possible to analyze thousands of genes or gene products simultaneously, resulting in a deep characterization of individual profiles.

Part 1 of this two - part report on that meeting describes factors influencing the choices of lot - release assays for vaccines and gene - therapy products (1).

With its uniquely comprehensive population data, deCODE is turning research on the genetic causes of common diseases into a growing range of products and services — in gene discovery, pharmaceuticals, DNA - based diagnostics, pharmacogenomics, in silico discovery tools, bioinformatics and medical decision support systems.

At the National Human Genome Research Institute, she's studying drug resistance in melanoma and in the lab performs Western blots on the gene products of SOX10 and PTEN.

Several gene rearrangements have been engineered and their protein products have been expressed in both normal cells and cancer cells to understand the effects of each rearrangement on cell function and targeted drug effectiveness.

First academic GLP center for performing biodistribution, toxicology / tumorigenicity and validation studies on gene and cell therapy products.

In addition to its emphasis on producing vaccines, the lab specializes in gene and cell therapies, including stem cell products.

We demonstrate that the formation of specific gap junctions between AVB and B motor neurons depends on interactions between unc - 7 and unc - 9 gene products, and that the expression of unc - 7 and unc - 9 influences formation of a large proportion of the gap junctions in the locomotory nervous system.

With its uniquely comprehensive population data, deCODE is turning research on the genetic causes of common diseases into a growing pipeline of products and services — in pharmaceuticals, gene and drug discovery, DNA - based diagnostics, pharmacogenomics, bioinformatics, and clinical trials.

If you have the «room service gene» and you buy a lot of convenience foods, then that's okay, just try to figure out which products you like that aren't made with animal products and are low in oil — because it's no good if you're avoiding animal products but just gorging on greasy food.

Bacteria in these products have lactose - digesting enzymes, and when they get a chance to grow in the gut they can transfer their genes to the bacteria on the lining of the gut.

These products will transmit the message to your bodily systems «switching on» health - promoting genes and promoting vitality.

And while the long - term effects of GMO products are not really known, there are studies that show that GMO anti-nutrients can be destructive to health and have a negative impact on gene expression.

I am on the hunt for a new serum or similar night product - and I've heard such good things about good genes.