Sentences with phrase «gene regions for»

These observations strongly support previous anecdotal evidence that P elements favor 5» gene regions for insertion.

Not exact matches

It appears that the gene for cystic fibrosis is found in a narrow region on chromosome seven.

Chromosome 2 and its extra centromere and telomere regions argues against special creation for the same reason male nip - ples and our defunct egg yolk protein gene argues against special creation.

When we consider coding regions for more or less critical genes, we can readily identify relationships between species.

Vast rice - growing regions in India, Bangladesh, and other countries, which are submerged during rainy season and rendered useless for rice production, have been made productive since the SUB1 gene that makes rice flood - tolerant was discovered and bred into popular existing rice varieties.

We've developed a range of tools and techniques to answer today's challenges and plan for the future, including gene technology, digital modelling and region - specific strategies.

IRRI is using genetic modification to help identify specific genes within these DNA regions that are responsible for these traits.

DOT is waiting for orders from Gov. David Paterson's office, DOT Region 3 spokesman Gene Cilento said.

The researchers then found that these same genes carry an additional risk for a phenomenon called spreading depolarization, a slowly - progressing, temporary electrical blackout of a region in the brain.

McCallion's strategy to make sense of all this data looks at the active genes in cells affected by a disease, groups of genes that interact with one another, their vulnerability to mutation and information from past scientific studies to filter more than a thousand gene candidates for disease risk down to just a handful within any one implicated region.

People who inherit a mutated version of the ATF6 gene are born with a malformed or missing fovea, the eye region responsible for sharp, detailed vision.

The race was on, with the two teams probing for candidate genes in that region to determine which bore the APECED mutations.

We did not find any evidence for a so - called «positive selection» but instead found that many gene variants linked to schizophrenia reside in regions of the genome in which natural selection is not very effective in the first place.

«By either skipping a mutation region or precisely repairing a mutation in the gene, CRISPR - Cpf1 - mediated genome editing not only corrects Duchenne muscular dystrophy mutations but also improves muscle contractility and strength,» said co-author Dr. Rhonda Bassel - Duby, Professor of Molecular Biology and Associate Director of the Hamon Center for Regenerative Science and Medicine.

Much like the association between BRCA gene mutation and the risk for breast cancer in women changed the approach to treatment / prevention, the identification of the Kallikrein 6 gene region may change the course of prostate cancer care through a blood test developed by the Lunenfeld - Tanenbaum Research Institute.

In the region surrounding the bead, the Barx - 1 gene — required for the development of molars — was dormant, evidence that BMP4 inhibits molar growth.

While several studies in the intervening years have investigated whether particular genes were responsible for modifying HD onset, this is the first to employ genome - wide association (GWA) analysis, which scans an individual's whole genome to identify chromosomal regions containing variants that are associated with the disease traits that are being studied.

Dwarki and Jaime Escobedo improved the AAV's ability to insert genes into chromosomes by adding a gene promoter region from cytomegalovirus, known to be active in the target for their gene therapy, muscle cells.

Purdue University researchers have pinpointed the gene that controls whether soybean seed coats are hard or permeable, a finding that could be used to develop better varieties for southern and tropical regions, enrich the crop's genetic diversity and boost the nutritional value of soybeans.

The gene could be modified to produce improved varieties for growing regions in which seed permeability can be a handicap, Ma said.

Last summer, Hamer and his colleagues made worldwide headlines when they announced that a region near the tip of the X chromosome probably contained a gene or genes for homosexuality.

Unlike whole - genome sequencing, this assay targets a select set of genes or regions with known associations with lymphoid cancer, allowing for more rapid detection of a variety of mutations.

The team integrated three, complementary gene sequencing approaches to look for mutations in tumor cells from SS patients: whole - genome sequencing in six subjects, sequencing of all protein - coding regions (exomes) in 66 subjects, and comparing variation in the number of copies of all genes across the genome in 80 subjects.

In May researchers at McGill University reported that the gene responsible for creating cells» protein - building machinery is more frequently methylated in the hippocampus — the brain region responsible for short - term memory and spatial navigation — of depressed suicide victims who suffered child abuse than in the brains of nonsuicide victims who were not abused.

Making up 98 percent of the genome, these regions do not code for proteins, but they contain «switches» that like a conductor control when and where genes are expressed.

Within the duplicate regions, Carmona - Mora and her colleagues discovered many switches, known as enhancers, important for controlling activity of genes.

Researchers looked for regions of each plant's genome that showed unusual patterns of variation consistent with past selective breeding acting on the VRN - D4 gene.

The results from McCammon's initial screen with zebrafish indicate that two genes in the 16p11.2 region could be key for brain development: fam57ba and doc2a.

Focusing on specific genes or regions is an especially good strategy for taxonomy projects, where variation in a few genes is often sufficient to place an organism on a phylogenetic tree.

Wu says, «Rather than looking for methylation changes at individual sites on the DNA, we looked at DNA regions or clusters on genes that might be more biologically meaningful than individual sites.

In particular, this region of the gene might serve as a landing place for cellular machinery that binds to the DNA and reads it, Nikolova said.

Epiviz implements multiple visualization methods for location - based data (such as genomic regions of interest) and feature - based data (such as gene expression), using interactive data visualization techniques not available in web - based genome browsers.

The gene (E2A) that codes for proteins with the properties of immunoglobulin enhancer binding factors E12 / E47 was mapped to chromosome region 19p13.2 - p 13.3, a site associated with nonrandom translocations in acute lymphoblastic leukemias.

In an independent effort, they introduced progressively smaller pieces of DNA from the large region known to contain the gene into embryos of the mutant mice, looking for the smallest piece that would correct the mutation in adult mice and restore a normal rhythm.

And large, genome - wide studies searching for genetic underpinnings for more common diseases, such as lung cancer or autism, have pointed to the nether regions of the genome between the protein - producing genes — areas that were often thought to contain «junk» DNA that was not part of the pantheon of known genes.

The gene that codes for this clotting protein has a very similar sequence across many plant species, and the researchers showed that the microRNA from dodder targets regions of the gene sequence that are the most highly conserved across plants.

This will cover a pilot project in a small region — about 1/1000 of the human genome — containing the genes for the major histocompatibility complex (MHC), proteins that present snippets of pathogens to immune cells.

Pugh added that the implications of this research could represent one step towards solving the problem of «missing heritability» — a concept that describes how most traits, including many diseases, can not be accounted for by individual genes and seem to have their origins in regions of the genome that do not code for proteins.

We call this process «speciation with gene flow,» and evolutionary biologists have long wondered if the genetic basis for this process is highly repeatable and if the genes involved are spread out across the whole genome or in a few discrete regions.»

«Capturing introns: Targeting rapidly evolving regions of the genome for phylogenetics: New protocol for targeting intron - containing genes to resolve evolutionary relationships between closely related species.»

What is more, the distribution among these groups was similar across all regions, which suggests «a common origin from a single gene pool for all dog populations,» the authors write.

Think of these promoter regions like on - off switches for next - door genes — when a promoter region is methylated, the switch is turned off and the gene it controls does not get read and expressed.

The researchers found that MYC may affect circadian rhythm and metabolism by promiscuously binding to promoter regions in key genes for maintaining these daily cycles.

Almost half of the ETV6 variants identified in this study occurred in the region of the gene responsible for binding to DNA.

Basically, the gene makes a molecule involved in preparing other genes for expression, helping to distinguish between regions of genes that should be manufactured and those that are silent genetic filler.

Scientists are only beginning to reveal, for example, how genetic variation in our 22,000 genes — as well as «non-coding» regions in the genome — help to shape complex traits, from a person's height to whether he or she develops autism.

Researchers thought they were hot on the trail of «gay genes» in 1993, when a team led by geneticist Dean Hamer of the National Cancer Institute reported in Science that one or more genes for homosexuality had to reside on Xq28, a large region on the X chromosome.

Rather, the researchers deleted what's known as enhancer regions for the Cyp27b1 gene.

By disabling the gene for that key protein in test animals, the scientists were able to home in on the mechanism by which that brain region, known as the suprachiasmatic nucleus or SCN, becomes the body's master clock while the embryo is developing.

It's the first time scientists have shown in selectively bred animals that the propensity for addiction is linked to differences in expression of genes for specific molecules in a specific brain region.