Sentences with phrase «gene regulation»
Gene regulation refers to the process by which genes are switched on or off in our cells. It controls when and how genes are expressed, or utilized, to make proteins that carry out specific functions in our body. Gene regulation plays a crucial role in determining our traits and characteristics, as well as in maintaining the overall health and functionality of our cells. Full definition
Are behavioral differences primarily due to changes in gene regulation or structure?
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She leads a multidisciplinary team integrating computational and experimental approaches to develop an understanding of gene regulation in immune cells.
The majority of these changes are not directly disease causing, but may still be relevant for gene regulation and the symptom severity.
Others are converted into strands of RNA that perform functions themselves, such as gene regulation.
We show that mutations and structural variations outside of the coding genome can interfere with normal gene regulation by disrupting the regulatory landscape.
It seems to be that we also get a fine - tuned as well as important gene regulation machinery that can be influenced by our environment and individual lifestyle.
The protein studied in the mold is part of a larger family of proteins also found in humans and involved in many essential biological processes including gene regulation and fatty acid metabolism.
Although gene regulation is complex and we still have a lot to learn, scientists do know of three ways in which our genes are turned off and on.
During her studies, she was interested in gene regulation and its impact on particular diseases, focusing on cancer.
We want to understand this observation through the investigation of gene regulation in the context of the epigenetic landscape.
This complex process of controlling the production of proteins is known as gene regulation.
«Lab - on - a-chip for tracking single bacterial cells: A novel lab - on - a-chip can be used to study gene regulation in single bacterial cells in response to dynamically controlled environmental changes..»
He focused on gene regulation at the transcriptional level during his postdoc.
Professor of Quantitative Biology of Gene Regulation at the University Medical Center Utrecht and Utrecht University since 2013
He's also eager to return full time to his HHMI - supported lab at the University of California, Berkeley, which has shifted its work on gene regulation from wet biochemistry to imaging single molecules in living cells.
This helps open the door to a functional dissection of the role of gene regulation during the evolution of modern humans.»
His career was at first devoted to neuronal cell biology, but during his postdoctoral work at Harvard Medical School, he decided to shift to the challenging question of how gene regulation programs control circuit formation in the brain.
Our laboratory focuses on understanding gene regulation in the cardiovascular system, skeletal muscle, and other metabolic tissues, with the ultimate goal of finding novel therapeutic strategies to prevent and treat cardio - metabolic and - myopathic diseases.
By creating a powerful new gene regulation system called CRISPR - on, Whitehead Institute researchers now have the ability to increase the expression of multiple genes simultaneously and precisely manipulate each gene's expression level.
This is the first example of cross-species gene regulation observed in a parasitic plant.
A physicist turned computational scientist, Graber comes to the MDI Biological Laboratory from The Jackson Laboratory, also located in Bar Harbor, where he focused on computational approaches to understanding post-transcriptional gene regulation and interactions, while also working intensively to process, analyze and interpret the genome - scale data sets generated within the Patient Derived Xenograft (PDX) cancer study program.
While the study represents a strong start for understanding how eQTLs affect gene regulation and expression, Engelhardt pointed out that she and her colleagues still do not have enough samples to understand trans - eQTLs as deeply as they would like.
The regulatory system to control redox balance involves sugar - dependent gene regulation and protein phosphorylation.
In this study, we will address these and other questions related to sestrin gene regulation using both in vitro and in vivo approaches.
In 1993, RIMB had 27 members, 25 of whom were involved with gene regulation and development.
This form of interference with bacterial gene regulation is also of pharmaceutical interest as it is known that pathogenic bacteria can protect themselves against attack by the immune system and the effect of antibiotics by forming biofilms, for instance on the epithelium of the respiratory system.
«How good bacteria control your genes: Chemical signals from gut bacteria influence gene regulation in the gut lining.»
In 2006, she became a Research Fellow at the Hormone Action and Oncogenesis group at the LRBGE and extended her work on GR biology and GR - target genes regulation in response to the ultradian secretion of glucocorticoids occurring naturally in mammalian systems.
The chemical modification of histones is thought to be a form of epigenetic information — information separate from our DNA — that controls gene regulation.
The team first set out to determine which RBPs were critical in RNA - mediated gene regulation by applying an RNAi screen to mESCs.
The involvement of NF - κB in β - interferon gene regulation reveals its role as widely inducible mediator of signal transduction.
The lab studies gene regulation via multiple lines.
«Important mechanism of epigenetic gene regulation identified.»
Storing a persistent memory in the brain involves dynamic gene regulation.
He pioneered the development of gene cloning technology and its application to the study of eukaryotic gene regulation.
What is known from global studies is that exposure to biologically active compounds, even at ng / L concentrations, can impact endocrine systems in nature and manifest as negative impacts like altered gene regulation, the presence of mixed reproductive tissues (intersex) and skewed sex ratios.
Small stretches of about 22 nt non-coding RNA, so - called microRNA or miRNA, are important for gene regulation through its binding to coding RNA sequences.
Read the Science article: Systematic Identification of Signal - Activated Stochastic Gene Regulation
The Computational Biology & Gene Regulation group aims at developing cutting - edge bioinformatics tools with immediate application to real - life biological problems.
«This paper lifts the lid off something that had been largely unsuspected: the tremendous species - specific dimension of human gene regulation,» says Trono.
Data - heavy phenomena like gene regulation may be too complicated for human scientists to pin down.
The modern study of gene regulation started in the 1950s, but researchers only started to unravel the complex array of histone modifications that fine - tune chromatin control of gene expression 20 years ago.