The modern study of
gene regulation started in the 1950s, but researchers only started to unravel the complex array of histone modifications that fine - tune chromatin control of gene expression 20 years ago.
Not exact matches
Moving from biochemistry to molecular biology, Palatnik
started investigating the role of microRNAs — tiny RNA molecules that are important in
gene regulation in most life forms — in the development of the plant Arabidopsis.
While the study represents a strong
start for understanding how eQTLs affect
gene regulation and expression, Engelhardt pointed out that she and her colleagues still do not have enough samples to understand trans - eQTLs as deeply as they would like.
Regulation is everything: It's important not to
start up
genes related to puberty during, say, infancy, or to activate
genes that are related to eye color in the bladder.
Further studies are needed to determine whether the specific use of transcription
starting points is a widely disseminated mechanism for
gene regulation.
But alternative
start codons account for a few of all
genes and are usually an indication of complex
regulation.
Professor Dockrell and her group are investigating mechanisms that regulate the production of immune - related proteins,
starting from
gene regulation (epigenetics),
gene expression (transcriptomics), cell phenotypes (flow cytometry) and finally protein release.