Sentences with phrase «gene segments encode»

Further, we have a keen interest in developing innovative methods for antibody modeling and design (Willis, J.; et al.; «Human germline antibody gene segments encode polyspecific antibodies»; PLoS Comput Biol; 2013; 9; 100304).

The NTRK fusions involved a gene segment encoding a tyrosine kinase domain.

Not exact matches

The pilot project tested a dozen or so of the most commonly used gene promoters (regions of DNA that facilitate gene transcription) and segments of DNA that encode ribosome - binding sites (sequences of messenger RNA that control protein translation) to determine whether they behave consistently in different cellular contexts.

June's team also wants to knock out two gene segments that encode different portions of the protein that makes up a T cell's primary receptor so that the engineered NS - ESO - 1 receptor will be more effective.

The exact composition of germline V gene sequences in an individual has been difficult to determine due to the highly repetitive nature of the genomic sequences encoding these segments, thus limiting our understanding of humoral immune responses.

The lead author, Karen Reddy, a postdoctoral fellow in the Singh laboratory, proposes that, such compartmentalization «implies the existence of DNA segments that encode for «nuclear addresses» acting like a nuclear zip code to direct or predispose genes to associate with specific regions within the nucleus.

For example, during T - cell development genes encoding the TRB molecules are assembled from multiple polymorphic gene segments that undergo rearrangements and selection, generating Vb — Db — Jb combinations that are unique in both length and sequence.