Sentences with phrase «gene sequences found»

Several other gene sequences found in the water and the ice came from pigs, chickens and cows.

More than 80 percent of the viral gene sequences he found were new to science.

Not exact matches

The researches found that the transgene was inserted into an active region of the genome, thereby disrupting the coding sequence and ultimately the function of the plants own OsAux1 gene.

From the sequence data, they found gene variants indicating that the man had dark skin and eyes.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

Fiers investigated the nucleotide sequence of the hemagglutinin gene of this duck virus and found that it was indeed very closely related to the strain that started the 1968 Hong Kong outbreak.

Practically nobody believed you could read a Neanderthal's genes until 2010, when the paleogeneticist Svante Pääbo successfully sequenced DNA from three Neanderthal skeletons found in Croatia.

The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further.

Researchers have sequenced the genome of the mould that causes blight and found it keeps a huge arsenal of potato - destroying genes, ready to evolve around whatever defences taters can muster.

Bernard Friedenson, associate professor of biochemistry and molecular genetics at UIC, looked at the DNA sequences of breast cancers from 21 different women and found mutations in genes involved in immunity in every one of them.

When researchers sequenced the sponge's genome in 2010, they found genes that help individual cells cooperate as a group: how to divide, send signals to one another, and distinguish between friends and outsiders.

Using gene sequencing tools, scientists from Johns Hopkins Medicine and the University of British Columbia have found a set of genetic mutations in samples from 24 women with benign endometriosis, a painful disorder marked by the growth of uterine tissue outside of the womb.

This cDNA lacks the non-coding «introns» found in the full sequence of a gene and is therefore not a product of nature — which is why the court ruled that it can be patented.

One route, first suggested by Burt in 2003, is to release a sequence that is resistant — effectively unrecognizable — to the guiding enzyme that finds cuts of DNA in a gene drive.

When the researchers compared the mRNA to a library of DNA sequences taken from the dendrites of neurons by James Eberwine of the University of Pennsylvania Medical Center, they found that it came from a single gene on chromosome X — the human version of which, when mutated, leads to fragile - X syndrome.

The team found that humans are equipped with tiny differences in a particular regulator of gene activity, dubbed HARE5, that when introduced into a mouse embryo, led to a 12 % bigger brain than in the embryos treated with the HARE5 sequence from chimpanzees.

«We were surprised to find cancer - linked genes in these benign endometriosis samples because these lesions do not typically become cancer,» says Papadopoulos, whose Ludwig Center laboratories performed the sequencing.

«Gene sequencing study reveals unusual mutations in endometriosis: Findings advance search for new ways to classify aggressive forms of the disease.»

Running their computer algorithm, the biologists found that 5300 genes contained complementary sequences to an miRNA — suggesting that the miRNA could control that gene's expression, they report in the 14 January Cell.

Although genes make up only 3 percent of the ENCODE sequence, the consortium found that 93 percent of the sequence is transcribed.

After gene - typing about 3,000 people, Sturm found that how OCA2 is expressed — and how much pigment a person has — is strongly linked to three single nucleotide polymorphisms (SNPs), or single letter variations, in a DNA sequence near the OCA2 gene.

A Canadian project called FORGE (finding of rare disease genes) aims to sequence children and families with 200 different disorders this year.

Using RNA sequencing, the researchers found multiple genes whose abnormal expression could lead to the high rate of death for cloned embryos, including failure to implant in the uterus and failure to develop a normal placenta.

To find out if the equivalent pea sgr was Mendel's gene, they picked out the location of its sequence from pea plants that varied in their seed color.

Sequencing the genome of one such organism, King and her colleagues found genes that code for pieces of the same proteins used for the binding of cells and communication between cells in animals — functions that would be unexpected in such an organism.

So we sequenced a gene involved in cell growth and found a correlation in about 85 percent of the patients: If you had a certain mutation in the EGFR gene, you responded to the drug; if you didn't have the mutation, you didn't.

But Aniket Gore of the US's National Institute of Child Health and Human Development and colleagues haven't found any disabling changes in the DNA sequences of eye development genes in the cavefish.

Gene sequencing is also allowing Jackson and Seed to track down the sources of microbes, both benign and malignant, that find their way into the newborns in the study.

She and her colleagues sequenced genomic DNA in the tumor samples but did not find any new driver gene mutations in the metastatic samples compared to the primary tumor samples, said McDonald, who completed clinical training under Iacobuzio - Donahue at Johns Hopkins.

Trent and others says that the same mechanism might be at work in genes linked to other cancers, such as breast and prostate cancer, which have been found to contain similar «harmless» sequence variations.

By comparing the genetic sequences of the mutant and normal flies, the researchers found that the forgetful flies had an inactive copy of a gene that he and his Chilean collaborators dubbed Volado (Vol)-- South American slang for absentminded.

Since the publication of the human genome sequence in 2001, scientists have found that the so - called junk DNA that lies between genes actually carries out many important functions.

The researchers then compared the expression of all genes in six parts of the brain of the two bird species using state - of - the - art molecular techniques, including next - generation sequencing — the first time these tools have been used to find brain properties related to innovation and problem - solving in wild birds.

Jim Van Etten and his colleagues at the University of Nebraska found the mysterious sequence within a gene carried by chlorella viruses.

Using a novel combination of technologies, including trio exome sequencing of patient / parental DNA and genetic studies in the tiny larvae of zebrafish, the EuroEPINOMICS RES consortium found that mutations in the gene CHD2 are responsible for a subset of epilepsy patients with symptoms similar to Dravet syndrome — a severe form of childhood epilepsy that is in many patients resistant to currently available anti-epileptic drugs.

«Finding the beginning of the active portion also enables us to identify the «promoter», that is, the DNA sequence that precedes the actual gene.»

In a new study, researchers are taking joint biopsy tissue from patients at the start of a new therapy and then six weeks later to see if they can find a predictor gene sequence that will clearly identify which patients respond to a particular therapy.

In the case of β - ionone, the smell associated with violets, McRae and colleagues managed to pinpoint the exact mutation (a change in the DNA sequence) in the odorant receptor gene OR5A1 that underlies the sensitivity to smell the compound and to perceive it as a floral note — people who are less good at smelling β - ionone also describe the smell differently, as sour or pungent, and are less likely to find it pleasant.

The goal of the human genome project was to use DNA sequencing to reveal all three billion DNA letters in our chromosomes and find all our genes.

The two teams sequenced the ruff's genome and found that a large chunk of chromosome 11, containing around 100 genes, is upside - down in the female mimics.

By comparing proteomic and RNA - sequencing data from people on different exercise programs, the researchers found evidence that exercise encourages the cell to make more RNA copies of genes coding for mitochondrial proteins and proteins responsible for muscle growth.

Researchers analyzed the genetic sequencing data of 718 multiple myeloma patients and found that African - Americans had increased mutations in the genes BCL7A, BRWD3 and AUTS2, while white people had more mutations in the genes TP53 and IRF4.

The gene - editing success appears to be largely due to one procedural change: The researchers introduced the editing system — the enzyme Cas9 and a guide RNA sequence that helps the editing machinery find its target — at the same time they injected the mutation - laden sperm into a healthy egg in the lab.

By deleting some of these «ultraconserved elements», researchers have found that these sequences guide brain development by fine - tuning the expression of protein - coding genes.

The team has also found that in hothead mutants, other faulty genes mysteriously revert to the sequence of earlier generations too.

To confirm and strengthen the findings, Zwick and his team are currently performing an independent study of individuals with Down syndrome, using whole genome sequencing to further delineate alterations in genes that perturb heart development in children.

«We're generating so much sequence data right now, from so many species, that it's relatively straightforward to look for signatures of selection in genes and to find good candidates for adaptations,» Montooth said.

Their findings indicate that intuition and signatures of selection in gene sequence may not be enough for scientists to conclusively solve the puzzles of molecular evolution.

More than two decades ago, in one of the first papers using gene sequences to find signatures of natural selection, scientists hypothesized that a molecular change in an enzyme gave the Drosophila melanogaster fruit fly species its superior ability to metabolize alcohol.

The researchers carried out fine - scale mapping, looking for parts of the DNA sequence that were specifically different in butterflies with different patterns, in three different Heliconius species, and in each case the cortex gene was found to be responsible for this adaptation in their patterning.