Viral
gene sequences from an enlarged set of about 200 Epstein - Barr virus (EBV) strains including many primary isolates have been used to investigate variation in key viral genetic regions, particularly LMP1, Zp, gp350, EBNA1 and the BART miRNA cluster 2.
Although
the gene sequences from human and chimpanzee remain very similar, previous studies in tissues other than the brain have shown that gene expression varies widely.
When scientists at the University of Delhi in India took soil samples from a pesticide dump and compared them with samples from a cleaner control site, they reported that the soil from the waste site contained a higher concentration of
gene sequences from certain bacterial groups, such as Pseudomonas, Novosphingobium and Sphingomonas, that are known to degrade common pesticides like hexachlorocyclohexane.
(C) Analysis of the variable
gene sequences from plasmablasts of the four pandemic H1N1 - infected patients indicated that ∼ 16.5 % of the pandemic H1N1 - induced plasmablasts were clonally related (shared identical VH and JH genes and CDR3 junctions).
Brunner is co-author of an article in the Aug. 24 issue of Nature Genetics about the study, which identified
gene sequences from Populus trichocarpa, commonly known as black cottonwood.
Brunner is a co-author of an article in an August 2014 issue of Nature Geneticsabout the study, which identified
gene sequences from Populus trichocarpa, commonly known as black cottonwood.
In the case of Knut, the team screened
gene sequences from plausible causative pathogens from tens of millions of individual DNA sequences.
Plachetzki's team then built a family tree of opsin
gene sequences from 22 highly diverse creatures, and found that opsins in hydras and humans evolved from those in a common ancestor.
In a cramped room at Johns Hopkins Medical Center, a machine the size of a refrigerator hums 24/7 to read
gene sequences from samples.
IBM's Watson, the supercomputer that famously won the TV quiz Jeopardy! in 2011, is analysing
gene sequences from the most aggressive types of brain tumours.
Robert Garry of Tulane University Medical Center and his colleagues analysed
gene sequences from the blood, spleen, liver and brain.
Then Mays, along with molecular biologist G. Michael Taylor of Imperial College in London, confirmed that the scars were signs of TB by identifying traces of
gene sequences from Mycobacterium tuberculosis in the 2300 - year - old remains.
We examined 13,355 prokaryotic ribosomal RNA
gene sequences from multiple colonic mucosal sites and feces of healthy subjects to improve our understanding of gut microbial diversity.
This involves «knocking out»
a gene sequence from the mouse genome and inserting an artificial gene sequence that has been generated in the lab.
Scientists who genetically engineer crops are looking to introduce a desirable trait into that crop, and they do so by inserting a new
gene sequence from another species into the target crop's genome.
Not exact matches
June 19, 2013 — A Cornell University study offers further proof that the divergence of humans
from chimpanzees some 4 million to 6 million years ago was profoundly influenced by mutations to DNA
sequences that play roles in turning
genes on and off.
People of every nation, color, language, belief, and condition are now known to possess in their body cells trait factors drawn by an inconceivably complex
sequence of intercombinations
from a common «
gene pool.»
Speaking about the film recently in Los Angeles, Cera — who in this film, takes some refreshingly bold steps away
from his usual one - note nerd persona — and co - writer / director Edgar Wright (who also did the zany cult classics Shaun of the Dead and Hot Fuzz) discussed the meaning of the film, the stretching Cera had to go through for the role, and the way in which the film's hyperkinetic action
sequences are really just the same as the dance scenes in Grease or a
Gene Kelly movie.
This dataset contains millions of genomic
sequences from a diverse set of rice varieties that, when combined with phenotyping observations,
gene expression, and other information, provides an important step in establishing
gene - trait associations, building predictive models, and applying these models to breeding.
From the
sequence data, they found
gene variants indicating that the man had dark skin and eyes.
Within decades, advances in
sequencing genes from ancient tissue could allow scientists to clone extinct dodo birds, saber - toothed cats, and woolly mammoths, says Jeffrey Yule, an evolutionary ecologist at Louisiana Tech University.
Analysis of physical characteristics in three - dimensionally preserved Fukangichthys skulls, as well as an examination of DNA
sequences from 12
genes, revealed that scanilepiforms are actually ancient cousins of polypterids.
Practically nobody believed you could read a Neanderthal's
genes until 2010, when the paleogeneticist Svante Pääbo successfully
sequenced DNA
from three Neanderthal skeletons found in Croatia.
In 1980 Fiers first
sequenced the
gene for hemagglutinin derived
from the human influenza strain H3N2 that circulated in 1965.
Now that genomes that can be
sequenced quickly and cheaply, deadly microbes have nowhere to hide
from the
gene police.
Rudenko and Oliver send DNA
from the cultured spirochetes for
gene sequencing at a lab at the University of Washington in Seattle.
The estimate of the number of human
genes has been repeatedly revised down
from initial predictions of 100,000 or more as genome
sequence quality and
gene finding methods have improved, and could continue to drop further.
They aimed to extract ancient DNA
from organisms trapped in amber to
sequence extinct
genes, recover dormant life forms and study protein evolution.
Taking advantage of the handful of complete human genome
sequences now available, the pair looked at how alleles — the two copies of each
gene we inherit
from our parents — differ within a genome.
Bernard Friedenson, associate professor of biochemistry and molecular genetics at UIC, looked at the DNA
sequences of breast cancers
from 21 different women and found mutations in
genes involved in immunity in every one of them.
Using
gene sequencing tools, scientists
from Johns Hopkins Medicine and the University of British Columbia have found a set of genetic mutations in samples
from 24 women with benign endometriosis, a painful disorder marked by the growth of uterine tissue outside of the womb.
The nucleation
gene appears to be unrelated to any of the more than a million
genes that have been
sequenced to date
from various organisms.
The even greater surprise is the recent discovery that epigenetic signals
from the environment can be passed on
from one generation to the next, sometimes for several generations, without changing a single
gene sequence.
When the researchers compared the mRNA to a library of DNA
sequences taken
from the dendrites of neurons by James Eberwine of the University of Pennsylvania Medical Center, they found that it came
from a single
gene on chromosome X — the human version of which, when mutated, leads to fragile - X syndrome.
These are
sequences made in the lab
from RNA — the template used to produce the proteins that
genes code for.
Back when life first took hold,
genes flowed around freely; genetic
sequences skipped around
from organism to organism in much the way they may soon on the Internet.
The team found that humans are equipped with tiny differences in a particular regulator of
gene activity, dubbed HARE5, that when introduced into a mouse embryo, led to a 12 % bigger brain than in the embryos treated with the HARE5
sequence from chimpanzees.
To derive an evolutionary tree of the TRIM5
gene, they analyzed and compared its complete protein - coding DNA
sequences from 22 African primate species.
However, the results of more recent phylogenetic analyses, derived
from comparisons between
sequences of specific
genes and of whole genomes, seemed to point to Ctenophora as the first group that parted company with the lineage
from which the rest of the animal kingdom (including sponges) evolved.
Project members also catalogued
sequences that mark areas where DNA unwinds
from the round histone proteins that maintain the shape of chromosomes, allowing the cell's transcription machinery to activate
genes in those areas.
But the predictability they did hope for could be threatened by an evolving policy on the patentability of
gene sequences, which is emerging
from the U.S. Patent and Trademark Office in Washington.
Lu's team will extract immune cells called T cells
from the blood of the enrolled patients, and then use CRISPR — Cas9 technology — which pairs a molecular guide able to identify specific genetic
sequences on a chromosome with an enzyme that can snip the chromosome at that spot — to knock out a
gene in the cells.
To more accurately reflect the mechanisms driving oligodendrogliomas, the researchers used RNA
sequencing to study directly, on a single - cell level,
gene expression in samples
from six early - stage human tumors.
To find out if the equivalent pea sgr was Mendel's
gene, they picked out the location of its
sequence from pea plants that varied in their seed color.
They downloaded
sequences of more than 700
genes from organisms ranging
from fruit flies to humans and compared
genes from closely related species.
To solve the puzzle, he and Malaysian colleagues collected bits of the flower of Rafflesia keithii
from Borneo and analyzed the DNA
sequence of a
gene called MatR.
The human (and all the other) genome projects were predicated on the reasonable assumption that spelling out the full
sequence of
genes would reveal the source of that diversity of form and attributes that so readily distinguish worm
from fly, mouse, chimp and human.
The earliest of the
gene sequences were taken
from four people of the Boncuklu community, who lived between 10,300 and 9,500 years ago.
In germline cells PIWI proteins silence the RNA
from jumping
genes by cutting them in
sequences of ~ 30 nucleotides that will become piRNAs.
Theoretically, it could be simpler and more targeted to use
gene blueprints
from sequencing data to build something that mimics microRNAs — binding to the same things the microRNA would — then embarking on a fecal transplant and ensuring it is safe.