Sentences with phrase «gene sequences in»

The exact composition of germline V gene sequences in an individual has been difficult to determine due to the highly repetitive nature of the genomic sequences encoding these segments, thus limiting our understanding of humoral immune responses.

But less than one percent of the gene sequences in the lake ice came from these sources.

The exact composition of germline V gene sequences in an individual has been difficult to determine due to -LSB-...]

She and other scientists are trying various techniques to streamline the gene analysis process, such as discarding less common gene sequences in a particular sample in order to focus on more prevalent ones.

In particular, the comparison of gene sequences in large numbers of patients and controls will be a key step in strategies for disease gene identification.

By using sequences of RNA that match specific gene sequences in a pest, RNAi should leave other species unscathed.

To his surprise, Lo found four different MLV - related gene sequences in 32 of the 37 patient samples.

Ultimately, Greider and CSHL's intellectual property office decided not to pursue the patent dispute — «I would rather just do science than spend my time in court,» she says — but she prevailed in ensuring that Avilion could cite the gene sequence in her dissertation.

The use of next - generation gene sequencing in newborns in neonatal intensive care units (NICUs) may improve the diagnosis of rare diseases and deliver results more quickly to anxious families, according to new research in CMAJ (Canadian Medical Association Journal).

The gene sequencing in the study was performed at SciLifeLab facility NGI - Uppsala.

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people.

After extensively characterizing the 47 - kb deleted region and flanking sequences from the wild - type mouse genome, we found evidence for only one gene sequence in the deleted region.

Not exact matches

Here's why: In the late 90s, technology emerged enabling researchers to rapidly sequence RNA and DNA — giving them the ability to isolate and record the activity of single genes.

That's attached to the progress of sequencing technology, the ability to edit cells, and other gene editing approaches have been transformative in the immunotherapy world in recent years.

June 19, 2013 — A Cornell University study offers further proof that the divergence of humans from chimpanzees some 4 million to 6 million years ago was profoundly influenced by mutations to DNA sequences that play roles in turning genes on and off.

The ability to locate the individual gene or gene sequence responsible for each disease could revolutionize biomedicine in the 21st century.

The order of sequence in which these bases are arranged determines the way the genes name each species.

People of every nation, color, language, belief, and condition are now known to possess in their body cells trait factors drawn by an inconceivably complex sequence of intercombinations from a common «gene pool.»

Speaking about the film recently in Los Angeles, Cera — who in this film, takes some refreshingly bold steps away from his usual one - note nerd persona — and co - writer / director Edgar Wright (who also did the zany cult classics Shaun of the Dead and Hot Fuzz) discussed the meaning of the film, the stretching Cera had to go through for the role, and the way in which the film's hyperkinetic action sequences are really just the same as the dance scenes in Grease or a Gene Kelly movie.

A separate genetics adviser will review, support and identify potential linkages in the genetics component of methane mitigation, including genomics (work on recombinant DNA and gene sequencing) and genetic interaction with environment.

This dataset contains millions of genomic sequences from a diverse set of rice varieties that, when combined with phenotyping observations, gene expression, and other information, provides an important step in establishing gene - trait associations, building predictive models, and applying these models to breeding.

The goal is to identify the genes necessary to install C4 photosynthesis in rice through different approaches, including genomic and transcriptional sequence comparisons and mutant screening.

In sequencing of the human genome, we learned that diseases rarely correlated to specific human genes.

The reliability and stability of these methods were described by Wu et al. 27 Illumina tag sequencing of the 16S rRNA gene V4 - V5 hypervariable region was performed at the Marine Biological Laboratory in Woods Hole, Massachusetts, using established methods.28, 29 Details of sequencing methods, quality control and filtering, and statistical modeling are presented in the eAppendix in the Supplement.

In the study, whole - exome sequencing and a targeted analysis of 90 genes implicated in heart disease were applied to 419 unrelated SIDS caseIn the study, whole - exome sequencing and a targeted analysis of 90 genes implicated in heart disease were applied to 419 unrelated SIDS casein heart disease were applied to 419 unrelated SIDS cases.

Blasting GM DNA into a plant arbitrarily and out of a sequence of genes that has evolved over hundreds of millions of years, in a manner aimed to optimise the functioning of an organism, is risky and unpredictable, and bound to destabilise the biochemistry of the plant.

In addition both constructs contain the constitutive Ubi promoter and nos T terminator, the bar gene conferring herbicide tolerance and may contain further sequences of bacterial origin including the neomycin phosphotransferase (nptI) selectable marker gene.

Using a gene - sequencing technique known as whole - exome sequencing that targets only the DNA that encodes proteins, the researchers cataloged virtually every significant DNA variant in three families in which the condition is common.

In addition, they also used exome sequencing and RNAseq — sequencing directly targeted to the SHIP1 gene — to examine the structure of the SHIP1 gene at both the DNA and the RNA level.

When looking into mechanisms that might affect the levels of SMN protein in neurons, the researchers scanned a genomic database called the UCSC Genome Browser and identified two genetic sequences that matched the opposite DNA strand of the SMN gene.

The DNA segments that carry genetic information are called genes, but other DNA sequences have structural purposes, or are involved in regulating the expression of genetic information.

While all cells in a specific organism share the identical DNA sequence, only a fraction of those genes are activated in a given cell type.

«If we could use gene editing to remove the sequences in an embryo that cause sickle cell disease or cystic fibrosis, I would say not only that we may do so, but in the case of such severe diseases, we have a moral obligation to do so.»

These are subjected to so - called next generation sequencing, a technique that sifts the vast genetic composite, ferreting out sequence variants (or alleles) caused by mutations in genes.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

The scientists compared the genetic sequence of five related strains of the species, looking for orphan genes and examining the life cycles of the various genes in the fly genome.

«It's a type of molecule called an antisense oligonucleotide, or ASO, that essentially is synthetic string of nucleic acid that binds a specific sequence in the gene.»

In 1972 he and his team were the first to publish the nucleotide sequence of a complete gene.

An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers — sequences of DNA that act to amplify the expression of a specific gene — in the genomes of humans and other mammals.

Within decades, advances in sequencing genes from ancient tissue could allow scientists to clone extinct dodo birds, saber - toothed cats, and woolly mammoths, says Jeffrey Yule, an evolutionary ecologist at Louisiana Tech University.

Analysis of physical characteristics in three - dimensionally preserved Fukangichthys skulls, as well as an examination of DNA sequences from 12 genes, revealed that scanilepiforms are actually ancient cousins of polypterids.

Practically nobody believed you could read a Neanderthal's genes until 2010, when the paleogeneticist Svante Pääbo successfully sequenced DNA from three Neanderthal skeletons found in Croatia.

Akey says determining the age of our mutations is made possible only by the stupendous increase in gene sequencing speed and power.

In 1980 Fiers first sequenced the gene for hemagglutinin derived from the human influenza strain H3N2 that circulated in 196In 1980 Fiers first sequenced the gene for hemagglutinin derived from the human influenza strain H3N2 that circulated in 196in 1965.

Rudenko and Oliver send DNA from the cultured spirochetes for gene sequencing at a lab at the University of Washington in Seattle.

Thanks to powerful gene - sequencing techniques developed in the past two decades during the race to decode the human genome, researchers are beginning to reconstruct what our ancestors» microbiomes looked like, potentially going back thousands of years.

In fact, the MESA researchers had included 46 different variants of the gene in their sequencing databasIn fact, the MESA researchers had included 46 different variants of the gene in their sequencing databasin their sequencing database.

They aimed to extract ancient DNA from organisms trapped in amber to sequence extinct genes, recover dormant life forms and study protein evolution.

Bernard Friedenson, associate professor of biochemistry and molecular genetics at UIC, looked at the DNA sequences of breast cancers from 21 different women and found mutations in genes involved in immunity in every one of them.

When researchers sequenced the sponge's genome in 2010, they found genes that help individual cells cooperate as a group: how to divide, send signals to one another, and distinguish between friends and outsiders.