Sentences with phrase «gene sequencing efforts»

He has helped generate and interpret mountains of data through microbial gene sequencing efforts, showing how microbes influence human well - being.

Not exact matches

Efforts are under way to close the remaining gaps; however, the sequence is of sufficient accuracy and contiguity to be declared substantially complete and to support an initial analysis of genome structure and preliminary gene annotation and interpretation.

The trust now plans to increase its spending from $ 160 million to $ 325 million over 7 years at the Sanger Centre near Cambridge — Britain's main gene sequencing laboratory — for more painstaking efforts to sequence a third of the human genome by 2005.

They enable molecular biologists and geneticists to selectively chop DNA into pieces, which can then be assembled into new versions of the gene, inserted into the genomes of other organisms, or sequenced as part of an effort to map an organism's genetic material.

The genes of 50 top bulls have been sequenced in an effort to understand how genes from temperate cattle have influenced important production traits in the modern Brahman breed.

Lo was encouraged by the variants because retroviruses are extremely mutable pathogens that change their gene sequences again and again in response to immune system efforts to kill them.

As large - scale genome sequencing projects, such as the Human Genome Project, near completion, the research community's focus is shifting toward efforts to determine functional information about these sequenced genes.

As scientists began to sequence human genes in the 1990s, sorting out the cellular locations of each gene's proteins became a priority, says Mathias Uhlén, a microbiologist at the Royal Institute of Technology in Stockholm, Sweden, and director of the Protein Atlas effort.

Previous efforts to sequence preserved mammoth DNA were error - prone or yielded insights into only a limited number of genes.

From these efforts, we identified a high - quality orthologous gene set across avian species, consisting of exons from 8251 syntenic protein - coding genes (~ 40 % of the proteome), introns from 2516 of these genes, and a nonoverlapping set of 3769 ultraconserved elements (UCEs) with ~ 1000 bp of flanking sequences.

The discovery, the product of a multiyear effort to provide a high - quality full genome map of the oil palm plant and to scour the sequence for genes of importance to both science and industry, has major implications for agriculture and the environment.

The convergence of several factors explains the trend: cheaper genetic sequencing technologies, the discovery of new oncogenes (genes that can cause a normal cell to become cancerous), a new generation of computers and bioinformatics that can analyze vast amounts of data, and a multibillion - dollar effort by researchers inside and outside the pharma industry to develop targeted drugs and companion diagnostics for cancer.

«Understanding how Cas9 is able to locate specific 20 - base - pair target sequences within genomes that are millions to billions of base pairs long may enable improvements to gene targeting and genome editing efforts in bacteria and other types of cells,» says Doudna who holds joint appointments with Berkeley Lab's Physical Biosciences Division and UC Berkeley's Department of Molecular and Cell Biology and Department of Chemistry, and is also an investigator with the Howard Hughes Medical Institute (HHMI).

Much of the work to isolate the PHS gene came from Gill and his colleagues» efforts to fully sequence the genome — think genetic blueprint — of common wheat.

Harvard University geneticist George Church will lead efforts to develop more precise gene - editing systems that distinguish between similar sequences.

We expanded on our genome sequencing efforts to include efforts in whole genome gene expression analysis and functional analysis of genome variation.

Sparked from the efforts of the T2D - GENES Consortium (Type 2 Diabetes Genetic Exploration by Next - generation sequencing in multi-Ethnic Samples; T2D - GENES) to aggregate and share results from large - scale T2D sequence and genotype datasets, the prototype T2D KP was built with seed funding from the NIDDK via the T2D - GENES Consortium and the Slim Initiative for Genomic Medicine in the Americas for T2D (SIGMA T2D).

Researchers with the Human Genome Project and various commercial ventures are racing to sequence the genomes of organisms in an effort to catalog all their genes.

Research Focus: I dedicate my time and effort to develop high - throughput sequencing technologies such as single cell transcriptomic, ChIP - Seq, ChIA - PET, and many more... The scientific rational is to understand better and with a different angle, the mechanisms of epigenetic regulation of gene expression in (rare) immune cells, pathologically relevant in many diseases such as asthma, SLE, tuberculosis...