Sentences with phrase «gene sequencing reveals»

16S rRNA gene sequencing reveals effects of photoperiod on cecal microbiota of broiler roosters — Jun Wang — PeerJ

Gene sequencing revealed two regions associated with major depressive disorder on one of the 23 pairs of chromosomes.

Biologists are keen to sequence the nematode's genome because much is already known about the creature's molecular genetics and developmental biology — a state of affairs that should help researchers to assign functions to the genes the sequence reveals.

The results of 16S rRNA gene sequencing revealed an increase in the relative abundance of the Gram - negative bacterial order Verrucomicrobia and Bacteriodetes, with a reduction in the Gram - positive order Firmicutes.

Not exact matches

Citation: Lemay DG, Ballard OA, Hughes MA, Morrow AL, Horseman ND, Nommsen - Rivers LA (2013) RNA Sequencing of the Human Milk Fat Layer Transcriptome Reveals Distinct Gene Expression Profiles at Three Stages of Lactation.

Analysis of physical characteristics in three - dimensionally preserved Fukangichthys skulls, as well as an examination of DNA sequences from 12 genes, revealed that scanilepiforms are actually ancient cousins of polypterids.

«Gene sequencing study reveals unusual mutations in endometriosis: Findings advance search for new ways to classify aggressive forms of the disease.»

Sequence analysis of the virus revealed numerous genes previously thought to exist only in cellular organisms.

As for the identities of Mendel's other four genes, Weeden says he expects them to be revealed in the next few years as more plant genomes give up their sequences.

The human (and all the other) genome projects were predicated on the reasonable assumption that spelling out the full sequence of genes would reveal the source of that diversity of form and attributes that so readily distinguish worm from fly, mouse, chimp and human.

So to reveal their function, biologists used the sequence information along with a technique called RNA - mediated interference (RNAi) to temporarily inactivate each of nearly 17,000 of the worm's genes.

The goal of the human genome project was to use DNA sequencing to reveal all three billion DNA letters in our chromosomes and find all our genes.

Our RNA sequencing analysis of NAFLD - HCC samples revealed squalene epoxidase (SQLE) as the top outlier metabolic gene overexpressed in NAFLD - HCC patients.

«The elephant results revealed noncoding sequences in the human genome that we predict may control gene activity and reduce the formation of mutations and cancer.»

Genome sequencing revealed that the isolated B. pumilus contained three unique gene clusters for the production of antimicrobial peptide compounds known as bacteriocins.

A comprehensive DNA sequencing of pancreatic cancer cases revealed not only a plethora of damaged genes, but potential diagnostic biomarkers that could help identify those with longer or shorter survival, and provide opportunity for new therapeutic interventions.

Using next - generation RNA sequencing and other advanced technologies, the researchers identified a previously unknown gene involved in betalain synthesis and revealed which biochemical reactions plants use to convert the amino acid tyrosine into betalains.

Large - scale gene - sequencing projects are revealing hundreds of autism - associated genes.

The genome sequence revealed much more variability than was expected in the genes that encode the amylase enzymes.

Gene sequences also reveal that HIV spread from Africa to Haiti — probably shortly after what is now the DRC gained independence from Belgium in 1960 — and arrived in the US around 1969.

In vitro experiments and high - throughput RNA sequencing revealed that CTCF deletion profoundly altered the B lymphocyte transcriptional program, shifting cells from a gene expression profile typical of the germinal center to one more similar to that seen in plasma cells.

Technologies such as RNA sequencing are revealing which genes are expressed in each individual cell.

SEATTLE — Apparently ending several years of uncertainty, an official of the U.S. Patent and Trademark Office (PTO) revealed here today that the government intends to grant patents on expressed sequence tags (ESTs), human DNA sequences of up to a few hundred base pairs in length that can be used to identify and detect the expression of specific genes.

Whole genome sequencing of modern and ancient horses unveils the genes that have been selected by humans in the process of domestication through the latest 5,500 years, but also reveals the cost of this domestication.

«Today, rapidly falling costs means that high throughput sequencing projects are revealing the entire gene sequences of ever more species, but the biological functions of most of these genes remain unknown,» said Dr. Olivier Lichtarge, professor of molecular and human genetics and director of the Computational and Integrative Biomedical Research Center at Baylor and senior author of the report.

DNA sequencing of sperm from the grandfather mice and their pups also revealed epigenetic marks on the gene encoding M71 that weren't seen in normal mice.

DNA sequencing of the ladybird's protein - coding genes revealed roughly 50 that help manufacture antimicrobial peptides, compared with 16 such genes identified in the red flour beetle, which the researchers examined for comparison.

More sensitive cultivation methods and precise 16S rRNA gene sequencing techniques have revealed that the human bladder hosts a significant microbiome and those diverse bacteria inside the bladder impact pediatric urologic diseases.

The sequence of the complementary DNA encoding pp40 revealed similarity to the gene encoding MAD - 3, a protein with mammalian I kappa B - like activity.

«A single genome does not reveal the large store of genetic diversity in rice,» says Leung, who notes that many important genes are not present in the previously sequenced rice lines.

The research is part of the International Cancer Genome Consortium (ICGC)-- a global project using the latest gene - sequencing technology to reveal the genetic changes driving the disease.

Analysis of genomic, epigenetic, and RNA sequencing data revealed that the combinations of mutations that lowered the levels of functioning BRCA1 and BRCA2 RNA — genes that produce the breast cancer tumor suppressor proteins — were associated with significantly better survival outcomes.

Gene sequencing provides an organism's genome sequence, but gene expression profiling reveals where and when in the body certain genes are actGene sequencing provides an organism's genome sequence, but gene expression profiling reveals where and when in the body certain genes are actgene expression profiling reveals where and when in the body certain genes are active.

Through a rapid gene sequencing test, the tiniest details of a tumor biopsy are uncovered, sometimes revealing one or more mutations in the patient's genes.

«It is also possible that these data will reveal that some previously identified disease - associated sequence variants actually fall within a formerly unrecognized primary miRNA gene, thereby raising the possibility that such variants may influence expression of the encoded miRNA,» Mendell said.

Researchers have sequenced the genomes of all 15 species of Darwin's finches, revealing a key gene responsible for the diversity in the birds» beaks.

Analysis of the DNA and encoded amino acid sequences of A14 and B9 revealed that the first two are clonal variants which aligned most closely to the germ line denoted VHH Vg (T Verrips, unpublished data) and that the sequence of B21 is highly divergent from both and also aligns to a different germ line V gene sequence Vu.

Genome sequencing of six children with autism has revealed mutations in a gene that stops several essential amino acids being depleted.

«Oil palm genome sequence reveals divergence of interfertile species in Old and New worlds» and «The oil palm SHELL gene controls oil yield and encodes a homologue of SEEDSTICK» will be published online ahead of print in Nature on Wednesday, July 24, 2013.

Interestingly, the results of our promoter analysis for all these genes revealed that 9 of 17 genes (COL13A1, CSF3, FSCN1, HG18, LTBP1, PELI1, PLOD2, SCNN1A, and TNFSF10) have perfectly matched consensus sequences of KLF4 binding site on the promoter regions, suggesting a potential possibility of controlling these genes by KLF4 although it is not clear whether these genes are cause or consequence of brain metastasis at this point.

Even for genes whose role in highly penetrant monogenic disorders has been well established, sequencing will reveal many variants of unknown significance.

In contrast to traditional genetic testing, which usually checks for variants in specific genes, high - throughput sequencing has the potential to reveal a number of secondary findings, i.e., genetic variants with medical relevance but not related to the condition that merited the test.

In the lead profile, Jansson represented those researchers investigating such diseases by using omics technologies - uncovering the DNA sequences, expressed genes, and metabolite signatures used to reveal links to microbial functions in the gut.

Explaining that Rick's gene sequencing had revealed a genetic condition called Hereditary Neuropathy with liability to Pressure Palsies (HNPP), the ClinSeq ® doctor asked if any of his brothers or sisters had it.

For instance, the mouse sequence revealed that mice have two genes related to the gene involved in Lowe's syndrome, an inherited metabolic disorder in humans.

More recently, the sequencing of the genomes of thousands of life forms is revealing just how many and what genes and the proteins they encode have been conserved from the Precambrian.

«The human genome sequence provided a blueprint of all the protein - coding genes in the human genome for the first time,» reveals Jan Ellenberg, Head of the Cell Biology and Biophysics Unit at EMBL Heidelberg, «this changed how we go about studying protein function.»

Both groups are analyzing the sequence to identify genes that will reveal how the pathogen causes disease and interacts with the plant host.

Comparisons of whole - genome sequences reveal the expansion of gene family clusters to be an important mode of genome evolution.

TEST CASE RESEARCHER Piroska Szabó, Associate Professor, Center for Epigenetics, Van Andel Research Institute ORGANISM Mouse METHOD RNA - seq In 2014, Szabó and colleagues reported how they'd used mouse embryonic fibroblasts to test whether the relatively new method of RNA sequencing could reveal known and novel imprinted genes.