Sentences with phrase «gene sets across»

However, the MIT team adapted it to randomly turn on or off distinct gene sets across large populations of cells, allowing the researchers to identify genes that protect cells from a protein associated with Parkinson's disease.

From these efforts, we identified a high - quality orthologous gene set across avian species, consisting of exons from 8251 syntenic protein - coding genes (~ 40 % of the proteome), introns from 2516 of these genes, and a nonoverlapping set of 3769 ultraconserved elements (UCEs) with ~ 1000 bp of flanking sequences.

Not exact matches

No particular genetic variant was shared across all synesthetes in all three families, suggesting there is no single «synesthesia gene» or set of genes.

Such meetings would have exchanged ideas as well as genes, thus setting off a chain reaction of innovation across the continent.

«This means that the odds of an individual animal making it across I - 15, surviving to set up a territory, successfully breeding, and then their offspring breeding so the genes are spread throughout the population is harder to have happen naturally than one would expect.»

The enrichment score (ES) for a single set was then defined as the greatest positive deviation of the running sum across all genes.

ONE - PARENT SAMPLE SET PARENTAL GUIDANCE RULES: Maternally methylated (red dots) and paternally methylated (blue dots) regions across the human autosomal chromosomes, based on studies of uniparental disomy samplesGENOME RES, 24:554 - 69, 2014 RESEARCHERS Kazuhiko Nakabayashi, Division Chief, Department of Maternal - Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan; David Monk, Principal Investigator, Epigenetics and Cancer Biology Program, Bellvitge Institute for Biomedical Research ORGANISM Human METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker for imprinted genes, though it's possible for patterns of differential methylation to exist in tissues where both alleles are expressed.

A broad range of biological processes, molecular functions, cell cycle pathways (Supplementary Table S5) and gene sets from the MSigDB (Supplementary Table S6) was enriched across these different modules.

The extensive data sets of allele - specific expression across multiple tissues have allowed us to identify imprinted genes and characterize their properties.

They focused their search on expression levels of two sets of genes, those that remained largely unchanged across all four species, suggesting that there was little room — or need — for improvement, and those that changed most dramatically, usually in the human lineage — an indication of powerful incentives to adapt to a changing environment.

A web - based tool in which users can upload their individual SNP data and obtain predicted expression levels for the set of predictable genes across the 14 different cell types.

Setton also identified a gene, called arrow, that when disrupted set off a cascade of cellular signaling events suggesting for the first time important relationships between segmentation and leg - development genes found across insects and arachnids.

To address this challenge, the International Mouse Phenotyping Consortium is creating a genome - and phenome - wide catalog of gene function by characterizing new knockout - mouse strains across diverse biological systems through a broad set of standardized phenotyping tests.

We present the raw data, and a description to support fresh analyses where researchers can look both within and across gene sets to further elucidate process that regulate metastatic colonisation.