Ensembl also integrates manually annotated
gene structures from external sources where available.
Life Extension Breast Health Formula helps protect the breast's DNA
gene structure from aging and environmental damage.
Not exact matches
In the clearest possible case, the ANT - OAR cell would differ
from a zygote on all of the parameters noted above: The ANT - OAR cell would have a pattern of
gene expression that is clearly distinct
from a zygote; it would generate a homogeneous population of cells rather than multiple cell types; it would undergo simple cleavage divisions and not produce any multicellular
structures.
Many thoughtful citizens, including eminent scientists, oppose the deciphering and altering of the human
gene structure, and are appalled by the proposed commercial uses of knowledge gained
from such activities.
The brainlike
structures created
from cells taken
from autistic children showed increased activity in
genes that control brain - cell growth and development.
Supporting that idea, the programmed
gene activity that builds teeth differs
from the instructions that build a jaw, even though both types of
structure grow in tandem.
Mammalian hairs and avian feathers develop
from a similar primordial
structure called a «placode»: a local thickening of the epidermis with columnar cells that reduce their rate of proliferation and express very specific
genes.
At the same time, coauthor Peter Adams,
from the University of Glasgow, published a previous study on the breakdown of the nuclear lamina in which he observed a peculiar protrusion, or blebbing, of the nuclear envelope into the cytoplasm, and these blebs contained DNA, nuclear lamina proteins, and chromatin (the nuclear
structures in which
genes reside).
But this is the first time, to my knowledge, that the direct link is established
from a novel
gene to a novel
structure to the invasion of a completely new ecological opportunity,» said Abderrahman Khila, an evolutionary and developmental genomicist at the Institute of Functional Genomics of Lyon, who led the study on the delicate insects called water striders.
PARTICLE acts in three different ways to prevent expression of the MAT2A
gene: 1) by winding around the MAT2A
gene to create a DNA: RNA triple helix
structure locking down the MAT2A
gene promoter, 2) by binding the messenger RNA product of the MAT2A
gene and preventing it being used for MAT2A protein synthesis and 3) transferring MAT2A messenger RNA into intracellular vesicles that are subsequently ejected
from the cell.
The comparative genomics analysis could «backtrack» the history of their
genes, and showed that the two bacteria have diverged 13.9 million years ago
from a common ancestor with a similar genome
structure, and possibly a similar lifestyle.
A
gene - therapy technique that aims to prevent mothers
from passing on harmful
genes to children through their mitochondria — the cell's energy - producing
structures — might not always work.
We can tell
from its
structure that the
gene helps regulate the activity of other
genes.
These could be used to build superconducting power lines, or even extremely strong magnets, which Balicas says could «open frontiers» in magnetic scanning of everything
from gene structure to brain activity.
Denis Duboule's team, at the UNIGE and the EPFL, Switzerland, compared the
structure and behavior of these
gene clusters in embryos
from mice and zebrafish.
Based on studies of other
genes related to FOXP2, the authors suggest that the loss of functioning protein
from one copy of this
gene might disrupt the proper growth of key speech and language
structures in the brain.
When the FGF8
gene was injected into or removed
from the front part of the brains of embryonic mice,
structures toward the front became elongated or foreshortened, respectively.
Through this technology, scientists obtained stem cells
from individuals with a genetic abnormality that confers increased susceptibility to schizophrenia, and they observed deficits during nerve development that could be traced to a specific
gene called CYFIP1, which helps maintain a nerve cell's
structure.
Short for «evolutionary developmental biology,» Evo Devo posits that the same set of master
genes, with differing on - off switches, controls the development of basic body
structures in animals ranging
from flatworms to humans.
Following the isolation and purification of microbial DNA
from all samples, we used community fingerprinting (ARISA) and high - throughput sequencing of the 16s ribosomal RNA
gene (V1 - V3) to describe the microbial community
structure in each group.
Biologists, biochemists and geneticists who need to visualize the anatomical location of cellular
structure, proteins / enzymes, mRNA, and reporter
genes within whole tissue are among those who can benefit
from this innovative product, which can be used with light microscopy, fluorescence microscopy, confocal microscopy and single / multiphoton microscopy.
Human perilipins 1 and 2 localize in transgenic C. elegans on the same
structures as proteins expressed
from W01A8.1
gene.
By probing the three dimensional
structure of this protein complex, called RNA - Induced Initiation of Transcriptional
gene Silencing (RITS), scientists
from Cold Spring Harbor Laboratory (CSHL) and their collaborators at St. Jude's Research Hospital have discovered new details of how its various parts or «domains» contribute to heterochromatin assembly and
gene silencing.
«This study identifies how the modification of the DNA
structure affects the binding of transcription factors, and this increases our understanding of how
genes are regulated in cells and further aids us in deciphering the grammar written into DNA,» study co-author Jussi Taipale
from Karolinska Institutet in Sweden said in a statement.
Originating
from molecular biology, Genomics branched out to become a vast field that includes research into the
structure and function of genomes, evolution and the effects of
genes on health and disease.
Many million different users consult these databases each year, seeking information on anything
from DNA sequences, protein
structures,
gene expression profiles, human genetic polymorphism or even comparative analyses of entire genomes.
This text covers topics ranging
from plant genome
structure and the key control points in how
genes are expressed, to the mechanisms by which proteins are generated and how their activities are controlled and altered by posttranslational modifications.
Structured Abstract
INTRODUCTION
Genetic interactions occur when mutations in different genes combine to result in a phenotype that is different from...
All human
genes have been mapped to representative PDB
structure protein chains (selected
from sequence clusters at 40 % sequence identity) to show which regions of a
gene are available in PDB coordinates.
By manipulating a specific
gene in a mouse blastocyst — the
structure that develops
from a fertilized egg but is not yet an actual embryo — scientists with the University of Florida's McKnight Brain Institute and the Harvard Stem Cell Institute caused cells destined to build an embryo to instead change direction and build the cell mass that leads to the placenta.
Furthermore, all data will be presented in a searchable «Tomato Expression Atlas,» a data - visualizing platform that will link
gene expression information with images
from a computer tomography (CT) scanner, which uses X-rays to render 3 - D virtual images that include internal
structures.
In a mutagenesis screen for new maternal
genes (Luschnig et al. 2004) we found that embryos
from 2R -225-5 homozygous mutant germline clones lacked cuticle
structures derived
from the anterior and posterior poles of the embryo (Figure 1, A and B), resembling the phenotype of terminal - class mutations.
For example, it is used to identify correlations between
gene sequences and diseases, to predict protein
structures from amino acid sequences, to aid in the design of novel drugs, and to tailor treatments to individual patients based on their DNA sequences (pharmacogenomics).
For his post-doc, Toor wanted to solve the crystal
structure of a group II intron RNA, a molecule formed
from a non-coding portion of DNA that delineates
genes in lower level organisms such as bacteria.
October 18, 2011 Young human - specific
genes correlated with brain evolution Young
genes that appeared since the primate branch split
from other mammal species are expressed in unique
structures of the developing human brain, a new analysis finds.
Using this, we have identified abnormalities in these
structures among 298 embryos
from mutant mouse lines carrying embryonic lethal
gene mutations produced for the Deciphering the Mechanisms of Developmental Disorders (DMDD) programme.
It is thought that disease results
from the combination of an abnormal
gene (causing an abnormal
structure of the SAA protein), and also infectious or environmental factors that cause systemic inflammation and so increase the production of this protein in affected cats.
They seek answers to questions about the
structure of the universe, the formation of our solar system and other planetary systems, the behavior and transformation of matter when subjected to extreme conditions, the origin of life, the function of
genes, and the development of organisms
from single - celled egg to adult.
It was Richard Dawkins, however, in his book The Selfish
Gene, who first introduced the construct of meme
structures as representing units of culturally relevant information that are transmitted
from brain to brain (i.e., memes are self - replicating units of information).