Sentences with phrase «gene studies»

But few biologists have the expertise necessary to tap the flood of data generated by gene studies and clinical trials.

To determine which variant of the receptor genes study participants possess, DNA was collected via saliva samples for genetic analysis.

The group hopes to examine the effect in clinical trials in the future, and plans to look at the function of the other six genes their study identified.

Even cells at the top of the hierarchy generally express only a subset of the stem cell genes studied.

In 1997, when few genome sequences were available, Hieter helped create XREFdb, a public database that linked the functional annotations of genes studied in model organisms with the phenotypic annotations on the human and mouse genetic maps.

Several candidate gene studies suggest that variations in HLA class 1 and other genes contribute to differences in antibody response to influenza vaccines [15], [69], [70].

«Cow gene study shows why most clones fail.»

«Gene study helps explain Legionnaires» probe complications.»

These genetic discoveries reinforce earlier gene studies implicating abnormal inflammation and fat metabolism in the disease.

«Given the small subset of autism genes we studied, I had no expectation that we would see the degree of spatiotemporal convergence that we saw,» said State, an international authority on the genetics of neurodevelopmental disorders.

«Risk gene studies have provided new knowledge that is important to those working in the field.

«Given the biologic relevance of mercury and selenium for human health and prior candidate gene studies demonstrating heritability, we anticipate discovery of major novel genetic regions that will greatly advance our understanding of the intersection between genes, dietary habits, and metabolism,» the research team told Harvard Public Health Now, a publication of the Harvard School of Public Health.

«Two new breast cancer genes emerge from lynch syndrome gene study: The findings suggest that genetic screening for breast cancer should be expanded to include MSH6 and PMS2.»

But Cavalli - Sforza says if the milk gene study holds up, it reinforces his own view that both theories are correct: Indo - Europeans migrated to Europe in two waves, first from Turkey and later from the Urals.

The soft body of D. cactiformis suggests that arthropods grew armour on their legs first, rather than their bodies, contradicting the results of some developmental gene studies.

Furthermore, high - resolution analysis of cytosine methylation in primary and transformed cells has found less aberrant methylation of CpG island promoters in transformed cells than had been previously hypothesized based on candidate gene studies [58].

Illinois postdoctoral researchers Johannes Kromdijk and Katarzyna Glowacka took the trio of genes studied at Berkeley and put them into tobacco plants for further testing in greenhouse and field experiments.

In the March 7, 2008, print issue of American Journal of Human Genetics, and published early online, the researchers used Affymetrix exon arrays to show that expression levels for nearly five percent of the 9,156 human genes they studied varied significantly between individuals of European and African ancestry.

One group of modified mice received minoxidil in their drinking water from weaning until 3 months, a second group was treated for only the two weeks before elastin gene studies, and a third group had plain water instead.

Gene studies revealed that minoxidil revs up not only elastin and elastic fiber genes but also more than 100 other genes related to blood vessel structure.

«We have identified and corrected a fundamental flaw in the current genomewide gene studies,» note the authors in the April 11, 2000 issue of the Proceedings of the National Academy of Sciences.

Some of the first high - profile disease gene studies therefore used dbSNP as a filter.

In the var gene study, hundreds of malaria genomes were sequenced in just a couple of years.

At one end of the hierarchy are stem cells expressing most pluripotency genes studied and few lineage specific genes; at the other end are fully committed cells that have extinguished the pluripotency program, and in between there is a continuous spectrum.

ZIG differential abundance detection method accounts for bias introduced by the under - sampling of microbial communities commonly found in large - scale marker gene studies.

«Gene study shows how sheep first separated from goats.»

April 17, 2013 Gene study helps understand pulmonary fibrosis A new study looking at the genomes of more than 1,500 patients with idiopathic pulmonary fibrosis, a rare and devastating lung disease, found multiple genetic associations with the disease, including one gene variant that was linked to an increase in the risk of death.

«We started with candidate gene studies, then moved to common variants and genome wide association studies, and then, most recently, leveraged exome sequencing, he said.

More than three gene mutations among the 10 genes studied were observed in 68 % of women with recurrent miscarriage and 21 % of controls.

Sutherland says the genes she studies are already silenced in healthy adult tissue, so theoretically researchers should be able to design therapies that re-silence them in cancer cells without side effects.

Gene studies can also be prohibitively costly.

«We don't know what the time period was between the two divergences, but we do know that half of the genes studied suggest that chimpanzees appear to be closer to humans, while the other half contradict this or are ambiguous.»

Gene studies were supposed to reveal the disorder's roots.

«The gene we studied (FLC) allows plants to respond to changes in the season.

The gene studies likewise tagged flying lemurs as the closest primate relative.

And 585 of the genes studied in this set — many involved in immunity to infections and reproduction — had more protein - altering mutations than silent ones.

The researchers found that the genes they studied did play a significant role in a person's food choices and dietary habits.

Indeed, studies looking at selection due to antibiotics have found that AcrAB, the genes we studied, were amplified.

The genes studied, called Microcephalin and ASPM, help determine brain size.

ACTN3 is probably the most convincing of the genes studied so far, the most consistently associated [with sports - related fitness].

The genes they studied — neurofibromin, p53 and RB — normally suppress cell division and cell survival.

Gene studies have failed to provide simple explanations for ailments like schizophrenia and MS. Torrey's theory may explain why.

His team performed embryology experiments, molecular cloning projects, and candidate gene studies, coming at the problem from several different angles at once.

Of 134 genes studied by the research team, 70 caused heart defects in fruit flies, and several of the altered genes are involved in modifying the structure of histones.

He continued his gene studies back in England, as head of the Laboratory of Gene Structure and Expression at the National Institute for Medical Research at Mill Hill.

Matchmaking can also help basic researchers learn how mutations in the gene they study affect humans.