Sentences with phrase «gene therapy strategies»

Our lab is developing gene therapy strategies to treat optic neuropathies, potentially blinding diseases of the optic nerve.

The third Objective (IRF3) brings together promising scientists and clinicians from the University of Pennsylvania and the Rockefeller University to combine gene therapy strategies, independently tested in humans, with the goal of engineering, growing, and administering killer cells that are uniquely empowered to find and kill HIV - infected cells.

«Despite extensive preclinical approaches, translation of gene therapy strategies into clinical trials is still a difficult and expensive process.»

«New nanoparticle gene therapy strategy effectively treats deadly brain cancer in rats.»

«We are encouraged by these promising results and look forward to optimizing the intracranial distribution of this new nanoparticle gene therapy strategy,» says Tyler.

Not exact matches

«Steep funding cuts for the federal health agencies are counterproductive at a time when innovative research is moving us closer to identifying solutions for rare diseases, new prevention strategies to protect Americans from deadly and costly conditions, advances in gene therapy, new technologies for understanding the brain, and treatments that harness the ability of our immune system to fight cancer.»

The proposed strategy reflects a continuing move toward combination therapies, particularly when it comes to epigenetic approaches, which target the mechanisms that control whether genes are switched «on» or «off.»

Muscle biologists Qi Long Lu and Terence Partridge at the Medical Research Council Clinical Sciences Centre in London, U.K., and their colleagues decided to combined the antisense strategy with a chemical often used in gene therapy because it is known to improve delivery of DNA into cells.

With further development, CRISPR - Cas9 - based gene therapy may offer a new clinical strategy for CGD, and perhaps other blood disorders.

However, the researchers believe that these results are proof of concept that gene therapy is a valid strategy against aplastic anemia; this therapy could also be applied to other genes — besides from telomerase — if a causal role for those other forms of the disease was discovered.

Although the gene / cell therapy strategy was highly successful in laboratory mice, the authors stressed that additional research and testing are needed before the therapy could be tested in humans.

«Gene therapy may represent a leading strategy to develop more efficient regenerative surgical treatments for numerous clinical needs,» they write.

«Even so,» the authors add, «cutting - edge gene therapy - based strategies in reconstructive procedures [are close] to setting valuable milestones for development of efficient treatments in a growing number of local diseases and injuries.»

Now, researchers report promising results from two small gene - therapy studies that mimic this strategy, hinting that the field may be moving closer to a cure that works for the masses.

«Experimental therapy for Prader - Willi syndrome shows promise in mice: Strategy activates silenced genes.»

Lysogene's Board of Directors is composed of accomplished leaders from the healthcare industry who bring their expertise in science, drug development, commercialization and strategy to developing and expanding our gene therapy programs.

Therapeutic strategies aiming at restoring the function of the implicated genes (gene and cell therapies) are very encouraging but not applicable in a near future to the variety of MDs.

The ability of cells to remain unaffected by HIV, in the absence of CCR5, has already been shown clinically, but this strategy has not been joined with gene therapy in making killer cells.

Overall, SR - Tiget represents a multi-disciplinary research environment, which provides a unique blend of scientific expertise in the development of innovative gene and cell therapy strategies, access to relevant preclinical models to evaluate their efficacy and safety, as well as competence in conducting early phase clinical trials.

This work, published in «Blood», was carried out by the CNIO Telomeres and Telomerase Group The treatment is based on the transport of the telomerase gene to the bone marrow cells using gene therapy, a completely new strategy in the treatment of aplastic anaemia

Clinical Applications and Bioprocessing Strategies Fundamentally, gene therapy should exceed the efficacy of existing therapeutic approaches and provide therapeutic strategies for unmet mediStrategies Fundamentally, gene therapy should exceed the efficacy of existing therapeutic approaches and provide therapeutic strategies for unmet medistrategies for unmet medical needs.

Lysogene's MPS IIIA gene therapy clinical trial strategy includes a partnership with the MPS patient networks to ensure families are well informed about our development program and are able to make informed choices concerning the best treatment strategy for their children.

We live in an age of medical wonders — transplants, gene therapy, lifesaving drugs and preventive strategies — but the healthcare system remains fantastically expensive, inefficient, bewildering, and inequitable.

Newer strategies include gene therapy, drugs that inhibit the metastasis process and chemotherapy - impregnated implants that release drugs in a slow, steady manner.