Sentences with phrase «gene this research focuses»
The Shank 3 gene this research focuses on represents a syndrome in which autism spectrum disorder (ASD) is common but, as the authors admit, the model only accounts for 0.5 to 2 per cent of ASD and intellectual disability cases.
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His research has spanned hematopoiesis, gene therapy, stem cell biology, genomics and cancer, consistently focusing on bringing the very latest research advances to patients with heretofore incurable diseases.
It is widely believed that damaged DNA and genes are the «driving force» behind the development of cancer and they are therefore the focus of cancer research.
For Molly Schumer, a postdoctoral fellow in genetics and evolutionary biology at Harvard Medical School, the fellowship will help fund her research on how evolutionary forces affect our genes, focusing in particular on a persistent trait that can cause melanoma in swordtail fish.
Medical research focusing on epigenetics is currently trying to block the enzymes that regulate these changes thereby silencing cancer promoting genes.
The focus of my research is population structure and gene flow in North American arctic canids: grey wolves and arctic foxes.
«It was kind of fun being at a medical school and known as the weird guy who worked with dogs,» says Modiano, who is now a professor of comparative oncology at the University of Minnesota College of Veterinary Medicine and the Masonic Cancer Center, where his research focuses on immunology, cancer cell biology, cancer genetics, and applications of gene therapy.
Most research on epigenetics has focused on the way everyday experiences alter patterns of gene activity in DNA during life through a chemical process of gene tagging called methylation, which usually silences genes.
Research into the drivers of genetic diversity has largely focused on gene expression, which controls how much of a given protein will be made, when, and in what tissue.
Most current research into the causes of cancer focuses on genes and environmental triggers.
Most DNA research focuses on genes that contain encrypted messages for making proteins, the cellular workhorses essential to life.
As large - scale genome sequencing projects, such as the Human Genome Project, near completion, the research community's focus is shifting toward efforts to determine functional information about these sequenced genes.
Fejzo, whose initial research focused on cancer genetics, has slowly built a case that genes play a role in the condition.
Their research, published in PLOS ONE, focused on one particular gene — TRIM29 — selected from a pool of 100 genes with regulatory patterns specific to normal breast tissue, to prove the link between breast - specific genes and the pathology of cancer.
The new research focused on just nine genes, those most strongly associated with autism in recent sequencing studies, and investigated their effects using precise maps of gene expression during human brain development.
While most research focuses on repairing the defective gene, researchers at EPFL have come up with a different strategy.
«Future research should focus on identifying common genes, immune responses and environmental exposures that may link these two diseases,» says first author Lauren Dalvin, M.D., a Mayo Foundation Scholar in Ocular Oncology.
Dr. Stoddart's main research focus is using autologous stem cells and gene transfer to repair musculoskeletal tissues using a cell therapy approach.
Much of the recent research into eye development has focused on the cascade of genes that turn on at different times to coordinate the process, but researchers thought electricity didn't play a role.
He has worked in the biotech industry as a research scientist for over 11 years with a focus on emerging technologies including gene targeting in mice, molecular analysis of transgenes using GFP variants at the single cell level, and developing flow cytometry reagent kits to speed up assay development time for researchers.
«While this research focused on flu infections, the mechanism we identified has implications for regulating many genes involved in anti-viral activity,» Thomas said.
New research into the causes of this baffling disorder is focusing on genes that control the development of the brain
The work from these two research groups in Barcelona now offers novel information for understanding this process, by focusing on a set of genes that act during development and are specific to certain tissues.
Much of the previous research on epigenetics has focused on the fact that everyday experiences alter patterns of gene activity in DNA during life through a chemical process of gene tagging called methylation, which usually silences genes.
In a 2003 research review, Nancy Roizen of the Cleveland Clinic and David Patterson of the University of Denver focused on a particular gene that is crucial to energy production and oxygen utilization inside cells.
Since a rough draft of the chimp genome became available in 2005, much research has focused on human gene sequences that are missing in apes.
«Our research focuses particularly on the activity of this gene and how it relates to neuroblastoma,» says Professor Marie Arsenian - Henriksson at the Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet.
Wondering whether genes might play a role, researchers at the Chulabhorn Research Institute in Bangkok, Thailand, led by environmental toxicologist Panida Navasumrit focused on the country's Ron Pibul district.
Because cancer cells acquire mutations in oncogenes — genes that can transform cells into cancer cells — to support their growth and survival, a great deal of research has focused on identifying oncogenes that could be targeted by cancer drugs.
In research published this week in the Journal of Neuroscience, University at Buffalo scientists and colleagues focused on a particular protein, called a transcription factor, that regulates gene activity necessary for the development of one type of retinal neuron, the horizontal cells.
His research currently focuses on determining the mechanisms and consequences of cohesin gene inactivation in human cancer.
They plan to use these findings to inform research focused on controlling and manipulating gene activity in genetically - engineered bacteria, which have many important medical and industrial applications.
Professor Dermitzakis» research focuses on the genetic basis of regulatory variation and gene expression variation in the human genome, the processes that govern non-coding DNA evolution.
His research activities currently focus on identifying metastasis suppressor genes in colorectal cancer.
Dr. Saptarsi Haldar's research focuses on how cells in the cardiovascular system control gene expression and how these gene control mechanisms go awry during disease.
«The bioinformatics tools have matured to the point that we can now find the proverbial «needle in a haystack,» meaning we can now identify genes and pathways that are unique to pathogenic microbes, which will focus future research efforts on these key pathogen - specific features,» Fouts said.
While the vast majority of research in this field is focused on developing stem cell, gene and tissue engineering therapies, these approaches have not yet delivered on their promise despite nearly two decades of research.
Michael Fischbach (University of California, San Francisco)-- A chemical biologist, Dr. Fischbach's research is on the human microbiome (all of our microbes» genes), focusing on the molecular mechanisms by which the microbiota influence the host organism.
This week's headlines include: GSK slims portfolio with sale of rare disease gene therapy drugs, The Focus Shifts in Alzheimer's Research, Healing process after breast cancer surgery may trigger...
His academic research focused on gene regulation and signal transduction mediated by ion channels and G proteins.
Her current research is focused on the identification of genes and molecular pathways for rare disorders and she is the Lead Investigator of the Genome Canada, CIHR funded «Finding of Rare Disease Genes in Canada» (FORGE Canada) and «Enhanced CARE for RARE Genetic Diseases in Canada» initiatgenes and molecular pathways for rare disorders and she is the Lead Investigator of the Genome Canada, CIHR funded «Finding of Rare Disease Genes in Canada» (FORGE Canada) and «Enhanced CARE for RARE Genetic Diseases in Canada» initiatGenes in Canada» (FORGE Canada) and «Enhanced CARE for RARE Genetic Diseases in Canada» initiatives.
Continued research will focus on identifying the mutated gene's location within the locus.
Dr. Innocentis NIH - funded research program is currently focused on the discovery of genomic determinants of efficacy and toxicity of cancer chemotherapy, integrating clinical genomic investigation with functional evaluation of gene variation.
«But how these defects develop at the genetic level has been difficult to pinpoint because research has focused on a small set of genes.
Professor Chris Jones talked to us about building a world - class research programme focused on finding the genes that drive childhood brain tumours, and his hopes for these hard - to - treat cancers.
Liu's scientific research focuses on the functional genomics of human cancers, particularly breast cancer, uncovering new oncogenes, and deciphering on a genomic scale the dynamics of gene regulation that modulate cancer biology.
His research focus at this time was on retrotransposons, «selfish» genes, which exploit host organisms to self - perpetuate.
Her research focuses on understanding how signaling pathways control gene expression, using T cells and other cells of the immune system as models.
Steve's research focuses on polyploid crops where he uses genomics and bioinformatics approaches to examine chromatin structure and the effect it has on gene regulation.
For the most part, the research has focused on the discovery of a complex cascade of genes that combine to form molecular pathways needed to help youthful cells, tissues and organs decide in which direction to take their first fateful steps — whether to go left or right.