Sentences with phrase «gene transcription processes»

Once inside the cell, it can interfere with bacterial cell signal transduction and gene transcription processes.

Not exact matches

The epigenetic impairments reflect changes that increase accessibility of chromatin, a process that enhances gene transcription, suggesting the impairments play an important role in addiction behavior.

PRMT1 is involved in a number of genetic processes including gene transcription, DNA repair and signaling.

«Our lab took part in analysing the group of RNA or transcriptome, that results from transcription, the process by which the instructions in the genes are read.

The researchers have compared various processes involved in gene expression, such as gene transcription and chromatin modification, and have repeated this in different tissues and cell types from both humans and mice.

When a gene is switched on, one of its strands is copied into the related chemical RNA, a process known as transcription.

Vitamin A and vitamin D are precursors to hormones that influence biological processes by entering the nucleus of a cell, binding to DNA, and altering the transcription of certain genes.

Histones are proteins vital for gene regulation, and histone modifications are central to regulation of many chromosome - related processes, including DNA replication, transcription and repair.

Disease processes often begin with mutations in the transcription factor, or in the DNA they bind to inside the nucleus of cells to regulate the complex interplay of genes needed for a healthy functioning body.

In most cases, the genes responsible for these processes are known as «transcription factors» — meaning that they are responsible for turning other genes on and off.

Jones, 62, is an expert in transcription elongation, a process that controls the expression of HIV and cancer genes; she has been at the Salk since 1986.

Rutgers University scientists have discovered the three - dimensional structure of a gene - specific transcription activation complex, providing the first structural and mechanistic description of the process cells use to turn on, or activate, specific genes in response to changes in cell type, developmental state and environment.

These include proteins which control important processes in the cells, for example the transcription factors which activate genes for the production of new proteins.

«The paper provides a dazzling snapshot of the process of transcription activation — the process whereby a gene is turned on in response to an instructive signal from the environment,» said Ann Hochschild, professor of microbiology and immunobiology at Harvard Medical School, who also was not part of the study.

At that point, a particular type of protein called a transcription activator can kick - start the molecular process by which a gene gets turned on.

Active genes produce molecular messages called RNA through a process called transcription.

In the Nature papers, the researchers compared gene transcription, chromatin modification and other processes that control gene activity in a wide range of mouse and human tissues and cell types.

The therapy consists in injecting into the hippocampus - a region of the brain essential to memory processing - a gene which causes the production of a protein blocked in patients with Alzheimer's, the «Crtc1» (CREB regulated transcription coactivator - 1).

A major process of gene expression is transcription, by which RNA is synthesized according to a DNA template.

Apart from that, the team has managed to show that the ANKRD55 proteins reside in the nuclei of the cells, and that suggests that they could play a significant role in the specific processes that take place in the cell nucleus such as gene transcription.

When a given gene needs to be transcribed to create new proteins, its promoter region must be unwrapped from the nucleosome so that it can be accessed by the factors involved in initiating the transcription process.

In fact, they found that TGF - β halts both the transcription of the p53 gene - the process by which cellular machinery reads the DNA code for a gene - and the subsequent process by which the corresponding p53 protein is produced, known as translation.

CDK7 is also involved in the process of transcription, a vital step in gene expression - the creation of proteins to carry out cell functions.

The three - dimensional organization of the genome represents a cell - type specific means to regulate gene transcription; however, we currently lack a detailed understanding of the architectural changes that occur during the generation of induced pluripotent stem cells (iPSCs) due to the inherent inefficiency of the reprogramming process [1].

10/10/2007 Researchers Reveal Repressor Protein Blocks Neural Stem Cell Development A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... More...

Control of plastid gene expression: 3 ′ inverted repeats act as mRNA processing and stabilizing elements, but do not terminate transcription

But in a recent study, researchers described a balancing act that seems more counterintuitive than most: Bacterial cells prioritize transcription — the process of making RNA transcripts of genes as the first step in protein production — over repairing double - strand breaks in their DNA.

Gene ontology (GO) analysis of genes within 250 kb of a PORE sequence revealed enrichment in processes such as transcription regulator activity (p < 0.001), sex determination (p < 0.005), insulin receptor signaling (p < 0.001), development (p < 0.0005), and protein phosphorylation (p < 0.005).

This process, known as gene expression, begins with transcription, in which a molecule called messenger RNA transfers the information in DNA out of the cell's nucleus and into the cytoplasm, where it is translated into amino acids that form proteins.

Heatmaps of the 50 concise clusters for All Genes, Transcription Factors and ESTs according to their timing of induction or suppression during the normal ES cell differentiation process.

The resource provides services including: processing of the samples (cells or tissues) to make high quality chromatin for ChIP, ChIP with a set of validated antibodies for histone marks (Promoter marks: H3K4me3 and H3K27me3, Enhancer marks: H3K4me1 and H3K27ac, Gene body marks for transcription activity: H3K36me3 and H3K79me2, and Heterochromatin mark: H3K9me3), ChIP with investigator preferred custom antibodies, and library preparation from ChIP DNA and multi-plexing for high - throughput DNA sequencing.

[9] This is achieved through gene transcription which is followed by the processes of translation and assembly of proteins into the contractile architecture.

Through processes called transcription and epigenetics, those critical genes switch on to guide the process.