DNA analyses of the Oaxaca corn revealed several signs of
gene transfer from transgenic plants, including a gene of Bacillus thuringiensis (Bt), a bacterium that produces a toxin lethal to common pests.
That's where genomic analysis can help: It turns out that Methanosarcina had acquired a particularly fast means of making methane, through
gene transfer from another microbe — and the team's detailed mapping of the organism's history now shows that this transfer happened at about the time of the end - Permian extinction.
Methanopyrus kandleri has relatively few
genes transferred from other organisms compared to other archaea.
A breakthrough came in 1996 with the introduction of Bt cotton, a genetically engineered crop containing
a gene transferred from the bacterium, Bacillus thuringensis, endowing the plants with a protein that kills some, but not all insects.
Not exact matches
Now instead they
transfer genes from the soybean plant into the yeast, grow the yeast, and then isolate the heme protein
from the resulting broth.
Christianity seems to have gotten some horizontal «
gene / meme»
transfer from many other places (e.g. ancient Greeks).
These include
genes from plants and organisms unrelated to rice that could not be
transferred using other breeding methods.
«Recombinant DNA technology», «DNA cloning», «molecular cloning» or «
gene cloning» all describe the process of
transferring a DNA fragment
from one organism to a self - replicating genetic element (a cloning vector) such as a bacterial plasmid, enabling the fragment to be propagated in an alien host.
They would be created through the process of lateral
gene transfer, in which microbes incorporate loose bits of genetic material
from other microbes into their own.
Bacteria lacking them to start with can simply borrow them (via horizontal
transfer of
genes)
from those that are better equipped.
By following the DNA -
transfer, scientists for the very first time showed an unknown mechanism called carry back in which pathogens were able to snatch
genes from far - related bacteria via the carry back mechanism.
«The big prizes — and there are going to be some very big prizes — are going to come
from transferring genes and knowledge between species,» says Gale.
Even distantly related bacteria can swap
genes with one another using a variety of techniques,
from direct cell - to - cell
transfer, called conjugation, to transformation, in which a bacterium releases snippets of DNA that other bacteria pick up and use.
In agriculture, for example, researchers
transfer genes from other organisms into crops to get certain characteristics.
The Nature study also adds to what is known about how
genes are
transferred from one species to another when individuals
from two closely related species mate.
As a possible step toward the goal of doubling food production by 2050 to feed our expanding human population, researchers have
transferred a key photosynthesis
gene from a blue - green algae into a tobacco plant, according to a Nature news story.
And both bacteria displayed the very same resistance
gene — most likely it had been
transferred to them
from bacteria living in the gastrointestinal tract.
The
gene works by making the plant mature more rapidly, thus speeding up the
transfer of these nutrients
from the leaves to the grain.
Some of these proteins are wasp venoms, suggesting that
genes from the wasp have been
transferred into the virus in a feat of natural genetic engineering.
The researchers found that there appeared to be a tipping point, where a patient would go
from having lots of individual mutations, but no cancer, to a situation where large pieces of genetic information were being
transferred not just between
genes but between chromosomes.
Goldstein and colleagues had reported that tardigrades imported about 17 percent of their
genes from foreign sources using a type of DNA swapping known as horizontal
gene transfer (SN Online: 11/25/15).
We assume that phages acquire resistance
genes from already resistant bacteria and then
transfer those
genes to other bacteria,» says Hilbert.
The team's next goal was to
transfer the
genes for making gas vesicles
from the water - dwelling bacteria into a different type of bacteria — Escherichia coli, which is commonly used in microbial therapeutics, such as probiotics.
So in an attempt to cure mice of hepatitis B, Kay's team flooded their livers with double - stranded RNA
from a
gene transfer vector.
PARTICLE acts in three different ways to prevent expression of the MAT2A
gene: 1) by winding around the MAT2A
gene to create a DNA: RNA triple helix structure locking down the MAT2A
gene promoter, 2) by binding the messenger RNA product of the MAT2A
gene and preventing it being used for MAT2A protein synthesis and 3)
transferring MAT2A messenger RNA into intracellular vesicles that are subsequently ejected
from the cell.
Bacteria share DNA with other organisms with which they come into contact, so an antibiotic - resistant
gene can
transfer from one type of bacterium to another, and a bacterial cell can become resistant to numerous antibiotics at once.
Their research, published in January, shows that bacteriophages can rapidly accelerate the evolution of human pathogens by
transferring genes from one bacterial species to another.
The new method circumvents the problem of not being able to culture many of these bacteria in the lab by
transferring genes from these bacteria into another bacterial species that is easier to work with.
Though initially labeled «slow» at school, in 1969 Lanza distinguished himself by
transferring genes from black chickens to white ones when he was just 14, a mere three years after scientists cracked the genetic code.
«The chance of the
gene being lost over and over again in the other lineages seems vanishingly small compared with a single
transfer from a metazoan to a bacteria.»
Joshua Lederberg who recently passed away discovered this — and like many other people who studied E. coli — got the Nobel Prize for his work and this was a huge help, because you could now
transfer genes from one E. coli to another and start to figure out what those
genes actually did.
Plant molecular biologists Fumiyuki Goto, Toshihiro Yoshihara, and their colleagues first isolated the ferritin
gene from soybean sprouts, and then used a soil bacterium to
transfer the
gene into the DNA of rice cells.
It noted that no harm to humans has been found
from GE crops, but concluded that
transferring genes does raise the risk of surprise effects.
But
gene transfer between kingdoms —
from animal to bacteria for example, or vice versa, has been much harder to document.
They say that
genes from wasps have been
transferred to several butterfly species, including the monarch, by symbiotic viruses used as biological weapons by parasitic wasps.
Rossolini said that it could have been
transferred from E. coli, as unlike K. pneumoniae, that bacterium frequently carries mcr
genes.
But they're good at ferrying
genes from one kind of bacteria to another in a process called horizontal
gene transfer.
Massive lateral
transfer of
genes encoding plant cell wall - degrading enzymes to the mycoparasitic fungus Trichoderma
from its plant - associated hosts
They did it by
transferring genes from maize into rice to create so - called Golden Rice; golden because it produces the same pigments that yellow vegetables do.
Horizontal
gene transfer of Chlamydia: Novel insights
from tree reconciliation — Hyaekang Kim — PLOS One
In an impressive example of horizontal
gene transfer, the whitefly has acquired 142
genes from bacteria or fungi, including some coding for enzymes that break down foreign chemicals.
The study, titled «Restoration of spermatogenesis by lentiviral
gene transfer: Offspring
from infertile mice,» was funded by the National Institutes of Health, the March of Dimes Birth Defects Foundation, the Wayne and Gladys Valley Foundation, and the H. N. and Frances C. Berger Foundation.
Draft genome annotation was
transferred from P. vivax P01 using RATT21 (version 1), and supplemented with the output of the Augustus22
gene finder, trained on P. vivax P01 as described in23.
Years after receiving a single dose of
gene therapy, patients on the hemophilia B trial continued to produce their own clotting factor
from the normal
transferred gene with minimal side effects.
We conclude that the risk of
transfer of AR
genes from GM plants to bacteria is remote, and that the hazard arising
from any such
gene transfer is, at worst, slight.»
Their first effort involves
transferring a
gene from jointed goatgrass, a wild relative of wheat, to confer resistance to stripe rust.
... the argument that occasional
transfer of these particular resistance
genes from GM plants to bacteria would pose an unacceptable risk to human or animal health has little substance.
Researchers identify a key
gene that allows C. difficile — a diarrhoea - causing bacterium found in hospitals and across the developing world — to be
transferred from person to person [Image Credit: CDC / Dr.
This biases our results towards assuming deeper origins of
genes than may be the case (if, for example, some phylogenetic incongruence arises
from horizontal
gene transfer), but we consider this property desirable as it makes our analyses conservative.
New coding
genes can arise in genomes through several processes, including
gene duplication,
gene fusion, de novo formation
from non-coding DNA, or lateral
gene transfer (LGT)
from another species.