Sentences with phrase «gene transfer into»

Gene Transfer into Mouse Embryos: Production of Transgenic Mice By Pronuclear Injection.

High level erythroid lineage - directed gene expression using globin gene regulatory elements following lentiviral vector mediated gene transfer into primitive human and murine hematopoietic cells.

Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus - based lentiviral vector system.

Not exact matches

Now instead they transfer genes from the soybean plant into the yeast, grow the yeast, and then isolate the heme protein from the resulting broth.

Then they can use classical plant breeding or genetic engineering to transfer those genes into desired cultivars.

The research, Marker - Aided Transfer of Beta - Carotene Biosynthetic Genes (Golden Rice I) into two Philippine Rice Varieties, was presented by Dr. Antonio Alfonso, project leader and the paper's main author.

Once specific genes associated with beneficial traits are identified, they can be more efficiently transferred into new rice varieties using other breeding methods.

By transferring genes that direct the production of fluorescent PER proteins into living flies, Kay and his colleagues have shown that each tissue carries an independent, photoreceptive clock.

«When you contaminate a site with resistance genes, those genes can be transferred into environmental organisms and actually increase the concentration of contamination.»

Such embryos were transferred into female goats, which produced offspring that were then tested for the presence of the newly integrated gene.

While previous vectors have only been able to penetrate the cochlea's inner hair cells, the first Nature Biotechnology study showed that a new synthetic vector, Anc80, safely transferred genes to the hard - to - reach outer hair cells when introduced into the cochlea (see images).

GENE therapy should become a more exact science thanks to the discovery that it is possible to predict where a transferred gene is likely to be inserted into the recipient's GENE therapy should become a more exact science thanks to the discovery that it is possible to predict where a transferred gene is likely to be inserted into the recipient's gene is likely to be inserted into the recipient's DNA.

Injecting donor cytoplasm into an egg involves transferring mitochondria and their genes as well.

To boost production of the enzyme in animals, U.C. Davis scientists have transferred the human gene for the enzyme into dairy goats.

They would be created through the process of lateral gene transfer, in which microbes incorporate loose bits of genetic material from other microbes into their own.

Issued last March to researchers at a little - known cotton seed company called Delta & Pine Land (D&PL) and the U.S. Department of Agriculture, the patent covers a technique for transferring three genes along with their genetic on switches into the seeds of genetically improved plants.

Three options are on the table: tweak cereals so that they form symbiotic partnerships with rhizobia as legumes do; colonise cereal roots with other types of nitrogen - fixing bacteria; or transfer the bacterial genes that make fertiliser directly into the crop plants.

For the dozens of labs at work on the problem, coming up with useful genes, known as transgenes, is not the hard part — it's how to transfer enough copies of the transgenes into free - ranging populations.

Some researchers have been trying an alternative route: engineering gene - delivery vehicles such as viruses to transfer neurotrophic - factor genes directly into brain cells.

In one such approach, researchers surgically remove brain cells, use viruses to transfer genes to the cells, and then graft them back into the animal's brain tissue.

Before Katlyn showed up at NIH, the doctors there were already well prepared: They had inserted healthy human ADA genes into a modified mouse retrovirus — a type of virus that can enter human cells and transfer new genetic material right into the DNA strands in their nuclei.

In agriculture, for example, researchers transfer genes from other organisms into crops to get certain characteristics.

As a possible step toward the goal of doubling food production by 2050 to feed our expanding human population, researchers have transferred a key photosynthesis gene from a blue - green algae into a tobacco plant, according to a Nature news story.

Next, the Stanford group plans to engineer their retroviruses to transfer IL - 4 genes directly into cells in live mice.

Some of these proteins are wasp venoms, suggesting that genes from the wasp have been transferred into the virus in a feat of natural genetic engineering.

Once transferred into the human genome, however, these alleles became subject to natural selection, which was more effective in the larger human populations and has removed these gene variants over time.

His team's approach is based on gene therapy, where a «tame» virus is harnessed to transfer a gene into target cells in the recipient.

RNA serves as the template for translation of genes into proteins, transferring amino acids to the ribosome to form proteins, and also translating the transcript into proteins.

Transfer these genes into crop plants, for instance, and you are a step closer to producing insecticidal crops — «no - spray» cotton, potato and corn fit for Utopian farms of the 21st century.

The first step in their process was to transfer the genes of the artemisinic acid pathway's core set of enzymes into the chloroplast genome of tobacco plants, generating what are known as transplastomic plants.

The team's next goal was to transfer the genes for making gas vesicles from the water - dwelling bacteria into a different type of bacteria — Escherichia coli, which is commonly used in microbial therapeutics, such as probiotics.

So far, Trewavas's team has transferred the gene into tobacco, potato and Thale cress (Arabidopsis thaliana).

«Gene therapy approaches fall into two main categories: (1) the transfer of a gene that stimulates the immune system and (2) the insertion of genes within the tumor that sensitizes the tumor to a relatively nontoxic «prodrug.&raGene therapy approaches fall into two main categories: (1) the transfer of a gene that stimulates the immune system and (2) the insertion of genes within the tumor that sensitizes the tumor to a relatively nontoxic «prodrug.&ragene that stimulates the immune system and (2) the insertion of genes within the tumor that sensitizes the tumor to a relatively nontoxic «prodrug.»

PARTICLE acts in three different ways to prevent expression of the MAT2A gene: 1) by winding around the MAT2A gene to create a DNA: RNA triple helix structure locking down the MAT2A gene promoter, 2) by binding the messenger RNA product of the MAT2A gene and preventing it being used for MAT2A protein synthesis and 3) transferring MAT2A messenger RNA into intracellular vesicles that are subsequently ejected from the cell.

Bacteria share DNA with other organisms with which they come into contact, so an antibiotic - resistant gene can transfer from one type of bacterium to another, and a bacterial cell can become resistant to numerous antibiotics at once.

The new method circumvents the problem of not being able to culture many of these bacteria in the lab by transferring genes from these bacteria into another bacterial species that is easier to work with.

Philip John of the University of Reading explained how American researchers at the University of California, Berkeley, have successfully transferred a gene into tomatoes and lettuce which manufactures a sweet - tasting compound called monellin.

Moreover, Boothby showed that yeast and bacteria artificially equipped with the genes could also survive dehydration, suggesting that they could potentially be transferred into crops to help them survive drought.

The virus transferred the blueprint of the human alpha - synuclein gene specifically into neurons of the midbrain, which then began producing large quantities of the foreign protein.

Plant molecular biologists Fumiyuki Goto, Toshihiro Yoshihara, and their colleagues first isolated the ferritin gene from soybean sprouts, and then used a soil bacterium to transfer the gene into the DNA of rice cells.

By transferring the gene for melanopsin into human embryonic kidney cells, synthetic biologist Martin Fussenegger of the Swiss Federal Institute of Technology in Zurich and colleagues made these cells light - sensitive as well.

Beyond the interest these lateral gene transfers evoke in evolutionary biology, these results highlight the risk gene transfers could cause, in case GM - parasitoid wasps are produced, as genes artificially introduced into wasp species used for biological control could be transferred into the genomes of the targeted pests.

But transferred genes can not be targeted to insert into a specific part of a chromosome.

In other words, transferring 45 of the largest - effect mammoth genes into an elephant all at once is unlikely to have a beneficial or useful outcome.

Genetic engineers directly transferred the gene for the toxic protein into crops to give them built - in resistance.

Since then he has continued to investigate new strategies to overcome the major hurdles to safe and effective gene transfer, translate then into new therapeutic strategies for genetic disease and cancer, and allowed new insights into hematopoietic stem cell function, induction of immunological tolerance and tumor angiogenesis.

They did it by transferring genes from maize into rice to create so - called Golden Rice; golden because it produces the same pigments that yellow vegetables do.

The recessive male - sterile gene contained in the IR36 mutant and the dominant male - sterile gene contained in PXDMS will each be transferred into five parental lines.

It might be interesting to ask if the gene editing would be of benefit to the embryo, would it be legal to transfer it into a woman to obtain a child?

The scientists demonstrated this by transferring T cells lacking the Tob1 gene into mice that had no immune systems but had normal Tob1 in all other cells.