Sentences with phrase «gene variant from»

According to senior researcher Shoukhrat Mitalipov, «Every generation on would carry this repair because we've removed the disease - causing gene variant from that family's lineage.»

To become ill, the patients (black) in the above group had to inherit a gene variant from both parents.

People who have inherited the gene variant from both their parents smoke 20 percent more than those without the special gene variant.

Pimas who had the most gene variants from European American sources were least likely to have diabetes.

While the dark skin of some Pacific Islanders can be traced back to Africa, gene variants from Eurasia also seem to have made their way back to Africa.

Mendelian genetic disorders are diseases and conditions that occur as a consequence of inheriting certain gene variants from each parent.

Not exact matches

Collaboration based on new findings from the Regeneron Genetics Center ® showing variant in HSD17B13 gene is associated with reduced risk of chronic liver diseases

Three of the darker - skin gene variants appear to have evolved from variants linked with less pigment.

Every gene in (almost) every cell of the body is present in two variants — so called alleles: one is deriving from the mother, the other one from the father.

From the sequence data, they found gene variants indicating that the man had dark skin and eyes.

We show that Neandertals shared more genetic variants with present - day humans in Eurasia than with present - day humans in sub-Saharan Africa, suggesting that gene flow from Neandertals into the ancestors of non-Africans occurred before the divergence of Eurasian groups from each other.

But as researchers pool data from thousands of cancer gene tests, some of those benign variants may be reclassified as dangerous, or may become informative in ways that hadn't been anticipated.

The IGF1 protein is crucial for the growth of mammals, including mice and humans, so Ostrander's group and other collaborators began collecting DNA from additional breeds to see if they also shared the same gene variant.

By collaborating with Konrad Oexle and colleagues from the Institute of Neurogenomics at the Helmholtz Zentrum, München, Germany, the researchers could conclude that the genetic variants in the gene seem to contribute to all three disorders.

Of the darker - skin gene variants, three appear to have evolved from less pigmented variants.

«Our finding from statistical analyses of all genes in the genome that SMCHD1 was the only plausible site of causal variants for arhinia — lack of a nose — was frankly shocking, since prior to our study no patients had ever been reported with both conditions.»

The team also examined data from a prior genetic study of children with asthma and found that a variant of the dectin - 1 gene — which reduces production of the receptor — is strongly linked to increased asthma risk.

Using genetic data from more than 36,000 people with a variety of autoimmune diseases, researchers found that one genetic variant in the gene that codes for the TYK2 protein...

In 2011, Science's editors will be watching a smaller detector at the Large Hadron Collider called LHCb, which will study B mesons in great detail; new techniques that should lead to the discovery of many more genes contributing to adaptation; an ignited fusion burn at the National Ignition Facility; broadly neutralizing antibodies, which are capable of disabling a wide range of viral variants; the first plug - in hybrid electric cars whose batteries are charged from a wall socket go on the market; and the results of the first phase III trial of a malaria vaccine.

Using genetic data from more than 36,000 people with a variety of autoimmune diseases, researchers found that one genetic variant in the TYK2 gene protects against a wide range of...

All land vertebrates carry a version of the FOXP2 gene, so some of the Oxford researchers then teamed up with colleagues from the Max Planck Institute for Evolutionary Anthropology in Germany to analyze what is unique about the variant in humans and to track how the gene had evolved in our ancestors.

Gene variants have been linked to elevated risks for disorders from Alzheimer's disease to breast cancer, and they may help explain why, for example, some smokers develop lung cancer whereas many others don't.

The increased risk closely correlates with the frequency of a gene variant previously associated with that adverse reaction, supporting recommendations to screen for that variant in patients from those populations.

Five decades on from the appearance of the first MRSA, multiple MRSA lineages have emerged which have acquired different variants of the resistance gene.»

Among the gene variants modern humans inherited from Neandertals are ones associated with higher cholesterol, increased belly fat, rheumatoid arthritis and schizophrenia, researchers learned from analysis of the new Neandertal DNA.

A study of people from an isolated village in the Netherlands reveals a link between rare variants in the gene NKPD1 and depressive symptoms.

Interestingly, many of the findings were variants of genes inherited from relatives who had not suffered from the syndrome.

Their analysis — which used DNA data from a Neandertal woman from the Altai Mountains in Siberia (SN: 1/25/14, p. 17) and 112,338 present - day British people — confirmed some links between Neandertal heritage and human diseases made by previous studies (SN: 3/5/16, p. 18), but didn't find evidence that Neandertal gene variants contribute to obesity.

Analyses of such variants, compiled from cataloging the genes from more than 60,000 people, are already offering doctors helpful insights into diseases such as schizophrenia and some heart conditions.

«And from there we can identify gene variants that may allow Joshua trees to survive rising global temperatures.»

Previous work has also shown that, following hybridization, many Neanderthal gene variants were lost from the modern human population due to selection.

Since people inherit two versions of each gene, one from each parent, they have either Val / Val, Val / Met or Met / Met variants of the gene.

Results from the analysis confirmed previous findings of some copy number variants already associated with autism, but they also found a host of other genes (SHANK2, SYNGAP1, DLGAP2 and the X chromosome — linked DDX53 - PTCHD1 locus) in which mutations seem to be linked to autism.

20 A variant of another gene, FGF5, produces long, silky coats, and curly hair comes from a mutation in KRT71.

They show that about 92 per cent of the population harbors bacteria with a variant of the gene sequence, according to a survey of public genome data from 250 adult humans.

Among all those genes, the researchers found 10 million variants — places within genes that varied from person to person.

Hendrik is preparing the publication of the most complete woolly mammoth genome yet, and Harvard geneticist George Church's team is already working to introduce specific DNA variants — genes for hair, tusks, subcutaneous fat and cold resistance — into cultured cells from Asian elephants (right).

A statistical algorithm then analyzes which gene variants the fetus has inherited from each parent and detects new mutations in the child's DNA.

Geneticists have pinpointed the gene variant that imparts this black fur and determined that it comes from domestic dogs that interbred with their wily cousins thousands of years ago.

Not only do black - furred dogs and wolves have the same gene variant, but the DNA surrounding the K locus is also quite similar — and quite different from that of gray wolves — suggesting that the variant was introduced when wolves interbred with domestic dogs.

Genetic screening later revealed that 24 percent of centenarians from Ashkenazi Jewish populations carry a variant in the CETP gene — an enzyme important for cholesterol metabolism — that reduces the level of the protein CETP in the blood and is linked to a lower prevalence of hypertension, cardiovascular disease and memory loss.

A drug prescribed to many patients with schizophrenia or bipolar disorder may decrease negative symptoms for people with a certain variant of the COMT gene, suggests a new study from researchers at Columbia University Medical Center (CUMC).

In the new study, researchers calculated genetic scores from over 30 genes for more than 3000 children with no family history of type 1 diabetes but with gene variants known to convey type 1 diabetes risk and who participated in the TEDDY prospective cohort study.

Approaching a biomedical problem from the informatics point of view — for example, Butte is studying which gene variants might predispose children to type 2 diabetes — allows a researcher to survey the available data without preconceived ideas.

The effects of this previously discovered gene variant were analysed by utilising data from the unique and extensive METSIM study.

Researchers once thought that the groups» distinct physiological and behavioral profiles stemmed from a variant in a single gene.

New research from the University of Eastern Finland shows that the APP gene variant protecting against Alzheimer's disease significantly decreases plasma beta - amyloid levels in a population cohort.

A schizophrenic from Brazil might have a combination of rare - variant genes contributing to the disease that is different from the mix in a schizophrenic from Norway.

Researchers suspect an autoimmune reaction is to blame because many people who develop narcolepsy — and just about everyone with the vaccine - associated form — have a specific variant in a gene in the HLA family, which helps the body distinguish its own proteins from those made by microbial invaders.

After analyzing human DNA from several populations around the world and examining primate genomes dating back to the shared ancestor of both humans and chimpanzees, researchers reached a striking conclusion that several gene variants linked to schizophrenia were actually positively selected and remained largely unchanged over time, suggesting that there was some advantage to having them.