Sentences with phrase «gene variants found»

To illustrate how it works in practice, Koenig offers the example of a professional hockey player whose profile shows that he has gene variants found in people who respond rapidly to lactic - acid threshold training.

The amount of variation within any human population, however, almost overwhelms those average differences: Just about any gene variant found among the Lapps or the Malays will eventually be found in Nigerians as well.

Mice bred to carry a gene variant found in a third of ALS patients have a faster disease progression and die sooner than mice with the standard genetic model of the disease, according to Penn State College of Medicine researchers.

The gene variant for white colour in pigs differs from the gene variant found in wild boar, with at least five different mutations, four of which are duplications of DNA sequences.

Not exact matches

The company will now be able to sell health risk reports on three variants found on the BRCA1 and BRCA2 genes, which are linked with a higher risk of breast, ovarian, and prostate cancer.

Collaboration based on new findings from the Regeneron Genetics Center ® showing variant in HSD17B13 gene is associated with reduced risk of chronic liver diseases

Mostly they are optimists, excited by the latest findings: the newly isolated gene variant that may help explain schizophrenia, the new telescopic images that reveal the violent births of distant....

For those who have MTHFR gene variants, supplemental folic acid has not been found to reduce the risk of miscarriage.

Health matters: A recent study found that women with good nutrition are more likely to have babies born with a cancer - suppressing gene variant

From the sequence data, they found gene variants indicating that the man had dark skin and eyes.

In this genome - wide association study, researchers found gene variants mapping to five loci associated with intrinsic epigenetic age acceleration (IEAA) and gene variants in three loci associated with extrinsic epigenetic age acceleration.

A large - scale genetic study published in The Lancet in 2012 found no relationship between gene variants that increased HDL and the likelihood of heart attack (though this research did not evaluate the SCARB1 variants).

As well as understanding the implications of finding this new variant of the botulism gene cluster in a non-clostridial species of gut bacterium, the team are interested in exploring how it might help in developing new treatments for diseases.

Joshua Akey of the University of Washington recently explored the average age of our species's gene variants, finding that most are very young.

Their landmark findings will open the door to identify gene variants controlling skin microbiota and to define their link to various diseases such as skin inflammatory disorders.

His team found a variant near the gene associated with earlier breast development in girls and, in boys, earlier voice - breaking.

All four teams focused their hunts on gene variations found in at least 10 per cent of the population, while Stefánsson thinks that rarer variants may play a more significant role in menarche.

An apparently new Variant of human serum albumin, albumin Naskapi, has been found in high frequency in the Naskapi Indians of Quebec and, in lower frequency, in other North American Indians.The family and population data of the albumin are consistent with its inheritance as a simple autosomal trait Controlled by a gene designated Al Naskapi.

When the researchers scanned the volunteers» genes, they found that two variants of the gene AVPR1A correlated strongly with musical ability (PLoS One, DOI: 10.1371 / journal.pone.0005534).

«For 20 years we've been looking for the gene and mutation behind my family's neuropathy, but we never found the variant,» he says.

«Machine learning finds tumor gene variants and sensitivity to drugs in The Cancer Genome Atlas.»

Among the DNA variants known to cause Alzheimer's or increase risk of the disease, none are found in the tau gene.

A hitherto - unknown variant of the gene which makes rogue prions, the proteins that spread the disease, was found in 51 survivors and their descendants.

The researchers found, for example, that extraversion was associated with variants in the gene WSCD2 and near gene PCDH15; neuroticism was associated with variants on chromosome 8p23.1 and gene L3MBTL2.

We used the LD signal strength as a guide to find our way to the true risk gene — the particular variant that actually caused the increased risk for lupus.»

Lupski was comparing genes in people with and without the disease in the hope of finding a gene variant unique to the condition.

The gene variant linked to graying is found only in people with European ancestry, and it has previously been associated with light hair colors.

It comes out in support of a ruling in March by a lower court that the patents, owned by biotech firm Myriad Genetics, should be revoked because they cover gene variants identical to ones that can be found naturally in women.

We did not find any evidence for a so - called «positive selection» but instead found that many gene variants linked to schizophrenia reside in regions of the genome in which natural selection is not very effective in the first place.

Reviewing thousands of genome wide associate studies (GWAS) to identify genetic variants in single nucleotide polymorphisms (SNPs), investigators at Dartmouth's Norris Cotton Cancer Center found that some alleles (one of a pair of genes located on a specific chromosome) are more frequently risk - associated with disease than protective.

«Our finding from statistical analyses of all genes in the genome that SMCHD1 was the only plausible site of causal variants for arhinia — lack of a nose — was frankly shocking, since prior to our study no patients had ever been reported with both conditions.»

The researchers studied DNA variants in the gene encoding the enzyme sucrase - isomaltase (SI), due to the observation that SI mutations are often found in hereditary forms of sucrose intolerance, whose main characteristics diarrhea, abdominal pain and bloating are also common in IBS.

The team also examined data from a prior genetic study of children with asthma and found that a variant of the dectin - 1 gene — which reduces production of the receptor — is strongly linked to increased asthma risk.

Last week, Nature reported that Pier Valerio Reinotti, an appeal court judge in Trieste, Italy, cut Bayout's sentence by a year after finding out he has gene variants linked to aggression.

A variant form of the gene was first noted in humans in a Hawaiian study of long - lived men of Japanese ancestry and has since been found in long - lived Germans, Italians, Ashkenazi Jews, and Chinese.

These discoveries build upon previous findings about genes linked to Alzheimer's, such as the APOE - 4 gene, which is a powerful marker for late - onset Alzheimer's disease; about 40 percent of those diagnosed have this DNA variant.

Using genetic data from more than 36,000 people with a variety of autoimmune diseases, researchers found that one genetic variant in the gene that codes for the TYK2 protein...

Using genetic data from more than 36,000 people with a variety of autoimmune diseases, researchers found that one genetic variant in the TYK2 gene protects against a wide range of...

However, the team found no association between the gene variant and diabetes, even though the two conditions normally go hand in hand.

McRae and colleagues found that the genetic variants associated all lie in or near genes that encode so - called odorant or olfactory receptors.

However, when specifically asked about a variety of possible incidental findings, only 57 % wanted to know if they were found to have a gene variant that would cause an unpreventable and serious illness, and only 47 % wanted to know about a gene variant of uncertain significance.

They found that people with the gene variant had the highest risk of side effects when they were given a statin called simvastatin, but this risk was much lower when they took pravastatin.

«Gene variant explains racial disparities in adverse reactions to urate - lowering drug: Findings support screening for risk - associated variant in Asian, black patients with gout.»

A team at Virginia Commonwealth University in Richmond recently found that three genetic polymorphisms — variants in the «spelling» of a certain gene — are connected to nicotine addiction.

Although the gene sequences were not identical to the Mikovits - Ruscetti XMRV gene sequence reported in Science, they were so close Lo believed he had found genetic variants of a single MLV - like virus species that likely included XMRV.

But some of the babies did not show this normal decrease in vagal tone during distressing periods; the researchers found that these infants who lacked an effective response at ages three and six months shared a particular variant of the DRD2 gene, which regulates receptors for the neurotransmitter dopamine.

Professor Peter Kraft at Harvard TH Chan School of Public Health, USA, says: «Given the size of these studies, we expected that we would find a lot of new breast cancer risk variants, but the studies tells us a lot more about which genes are involved, revealing many previously unsuspected genes and genetic mechanisms underlying breast carcinogenesis.

In humans, variants of the IL - 15R - alpha gene have been found in world - class endurance competitors, suggesting a target for gene therapies aimed at boosting the ability to exercise longer.

He said: «Over the past several thousands of years, the deficiency gene seems to have been positively selected, and is mainly found in north Europe, as have gene variants for larger height and size generally.

When population geneticist Andrea Manica and graduate student Marcos Gallego Llorente at the University of Cambridge in the United Kingdom analyzed the sequence, they found that the Mota man had brown eyes and dark skin, as well as three gene variants associated with adaptation to high altitudes; some peaks in the highlands reach 4500 meters, as high as the Matterhorn.