It's important to test for both homocysteine levels and the MTHFR
gene variation because while you may not have the gene that affects the methylation pathways, you may still have elevated homocysteine levels, which tells us the level of inflammation in our bodies.
Not exact matches
Because of these
variations,
genes may be expressed differently from one individual to another.
Variation in pigmentation among human populations may reflect local adaptation to regional light environments,
because dark skin is more photoprotective, whereas pale skin aids the production of vitamin D. Although
genes associated with skin pigmentation have been identified in European populations, little is known about the genetic basis of skin pigmentation in Africans.
The scientists estimate that these
gene variations were able to persist in Neanderthals
because Neanderthals had a much smaller population size than humans.
So geneticists have been focusing on the dog as a possible model for
gene searches
because this lack of sequence
variation may help them circumvent a frequent problem with studies in humans.
Geneticists classify traits like tooth size and shape as «complex»
because they are affected by DNA
variations within many
genes.
Because the
genes help produce nicotine's buzz, a team led by Robert Weiss, a geneticist at the University of Utah in Salt Lake City, wanted to determine if
variations in their sequences influence whether people develop a stronger addiction to cigarettes.
Although
variations in the NPAS1 and NPAS3
genes have been linked to brain disorders including autism, they aren't obvious drug targets
because their function is most important in early life.
Human hair color is a trait usually governed by many
genes, but study author Sean Myles, a geneticist at Nova Scotia Agricultural College in Truro, Canada, suspected things might be simpler in the Solomon Islands
because he saw almost no
variation in shades of blond hair.
Because of this level of
variation, natural selection acts on the level of individual
genes, not the whole genome.
Kwiatkowski and his team suspect that the
variation might be subject to something called balancing selection — just like the sickle cell
variation — where
genes are selected
because of their ability to protect against malaria, but are kept from becoming too common
because of their potential downsides.
Because many traits and conditions are the result of combinations of
genes and environment, we see a wide range of
variation for most traits in the population.
Many scientists looked to insects for natural homeotic
gene variation, Patel explained,
because insects have such diverse body plans.
Because of its rapid rise, the
gene becomes fixed in the genome with less
variation than a
gene that spread more slowly and was subject to the shuffling effects of recombination.
This is
because atopic dermatitis, better known as eczema, is often a result of
gene variation.