For this study, the team, which also included Bernard Crespi, an evolutionary biology professor at Simon Fraser University in British Columbia, and East Carolina University evolution professor Kyle Summers, focused on 76
gene variations most strongly related to schizophrenia.
Not exact matches
«Some people are protected from the effects of sleep deprivation by this particular
gene variation but, for
most of us, sleep loss does something to the brain that simply prevents us from switching gears when circumstances change.»
The sudden switch confounded
most of the sleep - deprived participants, but those who had a particular
variation of the DRD2
gene handled the switch as well as they did when well - rested.
Genetic
variations most strongly associated with high scores were found near the GATA2
gene — involved in the development of inner ear hair cells and the inferior colliculus.
That is, certain
variations in the children's CHRM2
gene appear to interact with parental negligence to produce the
most undesirable teenage behavior.
The
most obvious genetic difference between long - lived and short - lived strains of mice is
variation in the insulin / IGF
gene.
Patterns of genetic
variation along the genome also revealed a total of 121
genes selected by Scythian breeders,
most of which are involved in the development of forelimbs.
Genes with mammoth - specific changes were most strongly linked to fat metabolism (including brown fat regulation), insulin signaling, skin and hair development (including genes associated with lighter hair color), temperature sensation and circadian clock biology — all of which would have been important for adapting to the extreme cold and dramatic seasonal variations in day length in the Ar
Genes with mammoth - specific changes were
most strongly linked to fat metabolism (including brown fat regulation), insulin signaling, skin and hair development (including
genes associated with lighter hair color), temperature sensation and circadian clock biology — all of which would have been important for adapting to the extreme cold and dramatic seasonal variations in day length in the Ar
genes associated with lighter hair color), temperature sensation and circadian clock biology — all of which would have been important for adapting to the extreme cold and dramatic seasonal
variations in day length in the Arctic.
«Inherited
gene variation linked to an increased risk of the
most common childhood cancer.»
Researchers have discovered that protection from the
most severe form of malaria is linked with natural
variation in human red blood cell
genes.
Mutations affecting adult haemoglobin production are among the
most common of all genetic
variations, with about 5 per cent of the world's population carrying a defective
gene.
Additional examination of the two
genes in anoxeria - prone families gave the researchers a handle on which DNA sequence
variations conferred the
most risk.
Although
variations in the NPAS1 and NPAS3
genes have been linked to brain disorders including autism, they aren't obvious drug targets because their function is
most important in early life.
While a handful of food -
gene interactions have been studied before — lactose intolerance, for instance, is known to be caused by a
variation in the lactase
gene —
most are only now being charted.
The malarial
genes under the
most intense selection pressure — those with the
most variation, generated over a millennium - long cat - and - mouse game with the immune system's antibody response — are the ones that encode the identifying proteins on the surface of the parasite.
However, the combined effects of many different
genes cause
most variation among individuals.
Four
genes, all with synaptic function, have the
most case - only
variation: neuronal cadherin (CDH2), catenin alpha2 (CTNNA2), ataxin - 1 (ATXN1), and plasma glutamate carboxypeptidase (PGCP).
Because many traits and conditions are the result of combinations of
genes and environment, we see a wide range of
variation for
most traits in the population.
Most of the DNA
variations in AMD patients are found outside of the
genes, and it is extremely hard to know whether these variants are actual mutations and what
genes they affect.
In contrast to Mendelian disorders (e.g., Huntington's disease, sickle cell anemia) in which
variation in a single
gene causes disease, common complex disorders, such as heart disease, diabetes, and
most cancers, develop as a result of both genetic and environmental factors.
High
gene copy number
variation (CNV) among membrane - bound transporters, a class of proteins previously implicated in drug resistance, was found for the
most highly differentially expressed
genes.
This paper provides the
most comprehensive analysis so far of
variation in specific EBV
genes relevant to these diseases and proposed EBV vaccines.
Human genetic studies have identified novel DNA
variations in the genome associated with AMD, but
most of them are not located within
gene protein - coding regions, making their study a challenge.
The scientists say they have isolated two
genes,
variations in which lead to the hyper - friendliness and tail - wagging sociability that
most dogs exhibit.
The traditional color, produced when one or both
genes have the dominant allele, is commonly referred to as black or black and rust (also called black and tan), while the
most common
variation, due to both
genes having the recessive allele, produces what is called a red or red and rust Doberman in America and a «brown» Doberman in the rest of the world, which is primarily deep reddish - brown with rust markings.
Most breeds are fixed for either curly or not - curly, but in breeds where there is
variation, dogs may now be tested to see if they carry zero, one or two copies of the curly or non-curly versions of the KRT71
gene.
Dogs do make the
most of that lower number of
genes - dogs are believed to have more physical and behavioral
variations that any mammal on Earth.