Sentences with phrase «general dysfunction of»

Both witty and wrenching, the book details the neglect, abuse and general dysfunction of Ruta's childhood, which will make you root for her as she works through her issues and overcomes her own addictions — ultimately realizing that she must leave Kathi behind to live a healthy, productive life.

Not exact matches

While giving examples of the team's management dysfunction, Fox Sports reported that the Bills» general manager — normally in charge of personnel matters — wasn't even aware that coach Rex Ryan had been fired until owner Terry Pegula told him so.

Otherwise would be found in wealth or asset to GDP ratio's, providing notions of wealth accumulation and success to development model, and thus expectations, credence effects, enabling the general dysfunction overall.

Having stumbled across this thread, after having been absent for several years, I can't say I am too surprised with some of general movement dysfunction.

In general, persons who use heavy, inflexible defenses, are unable to sustain relationships of trust and mutuality, cope ineffectively, become disorganized or regress quickly when confronted with everyday crises and responsibilities, and are very dependent on others for sustaining their necessary sense of worth and power, suffer from ego weakness and dysfunction.

The etiology of PPD is unclear and is varied from woman to woman, but certain factors are suspected to contribute to its development: hormonal fluctuations, any preexisting medical problems, personal or family history of depression, marital dysfunction or general lack of support and social network, immaturity and low self - esteem, negative feelings about the pregnancy, lack of sleep, financial concerns, premature or special needs child, multiple pregnancy, traumatic birth, chronic stress factors, and neurotransmitter deficiencies.

Sen. Neil Breslin, who, as I mentioned earlier today, is facing an active primary challenger in Luke Martland, has been striving to put some distance between himself and the dysfunction of his Democratic conference at a time when voter disgust with Albany — and incumbents in general — is running very high.

Given that Tony Avella invested his time in writing a letter back in November, 2006 that questions the many nebulous and dehumanizing practices that continue to flourish in the present day at the New York City DOI and MTA Office of the Inspector General (who, collectively have misbehaved like unresponsive tyrants with no agency from above to challenge their utter dysfunction), I have long ago lost my illusion with honest, ethical leadership that stands by their constituency until a matter is thoroughly resolved.

The day before the primary, Long had called Paladino a sure loser in the general election and «a dangerous candidate» for Republicans — a comment that Long amended slightly Wednesday as he answered press questions with Paladino at his side: The candidate was dangerous, Long said, «to the liberals of this state and to the dysfunction of Albany.»

Cuomo was attorney general at the time and ran for governor largely against the era of dysfunction in Albany.

«Female athletes with exercise - induced menstrual dysfunction (associated with low estrogen levels) often have disordered eating behavior, which may impact their reproductive and bone health,» said lead researcher Madhusmita Misra, M.D., M.P.H., professor of pediatrics at Harvard Medical School and a pediatric endocrinologist at Massachusetts General Hospital in Boston, Mass..

Physician David Nathan, director of the diabetes center at Massachusetts General Hospital in Boston, notes in an email message that «what is ironic here is that [free radicals are] generally thought to be bad in human diabetes,» because they lead to dysfunction in the cells that make insulin and vascular complications.

A common consequence of bTBI in general is pituitary hormone dysfunction, which can occur even without mechanical head trauma and can interfere with the soldier's recovery, long - term health, and overall well - being.

In general, women appear to exert higher HPA sensitivity and therefore tend to be at higher risk, than males, of diseases associated with HPA dysfunction.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

«I support routine screening of the general population for thyroid dysfunction at the start of pregnancy and especially when seeking fertility treatment or struggling with miscarries,» he added.

This is good, but by and large, this is usually missed until after many miscarriages because people don't think about this, because physicians don't think of the general picture of stress, of the thyroid involvement or the adrenal dysfunction when a young, otherwise healthy woman comes into the office after just having a miscarriage.

General health choices over the course of years contribute to kidney dysfunctions, so it's imperative that you take care of your body.

Possible Implications: General indication of adrenal gland dysfunction.

Muscle imbalances occur due to nervous system dysfunction which can be the result of injury, pain, nutritional imbalances, organ dysfunctions, and other health issues, including general stress.

As a general maintenance dose, the authors of the study suggested individuals take a 500 mg, or more, daily dose of vitamin C during periods of stress, deficiencies, or anyone dealing with endothelial dysfunction.

Particularly notable are the obsession with technology and surveillance from Benny's Video, here updated from VHS to smartphones and the Internet; the racial suspicion of Code Unknown; the revenge nightmare from Hidden; the euthanasia theme from Amour (which also featured Trintignant and Huppert as father and daughter, suggesting a sequel of sorts), as well as more general themes of family dysfunction and the obliviousness of the well - to - do towards immigrants — it's no coincidence that the film takes place in Calais, yet never once shows the Migrant Jungle.

That's a shame, since the same basic dysfunctions that ail general education afflict special education too: middling (or worse) teacher quality; an inclination to throw «more people» at any problem; a reluctance to look at cost - effectiveness; a crazy quilt of governance and decision - making authorities; a tendency to add rather than replace or redirect; and a full - on fear of results - based accountability.

Still, the more apt comparison might be to Random Family, Adrian Nicole LeBlanc's 2003 book about two young women caught up in a suffocating web of destructive relationships, teen pregnancy, drugs, crime, and general dysfunction in the South Bronx.

The dysfunction of the infant American government was nothing compared to the internecine warfare of the British generals, who spent much of their energy scheming against each other.

Orbital disease is a general term used to describe dysfunction of any part of the bony orbit or its soft tissue contents.

They have been able to skirt federal regulation largely because of general dysfunction in Washington DC.

Create Resume EDUCATION: Pre Doctoral: University of Washington College of Arts and Sciences, 1958 - 1959 Dental School, 1960 - 1964 Post Doctoral: Residency in General Anesthesia, Washington Hospital Center, 110 Irving St., Washington D.C. Perio study club 1983 — 1985 cents 210 hours TMJ Dysfunction study club 1986 — 40 hours Mini Endo Residency 1994 ---LSB-...] Continue Reading →

In general, the original C (social dysfunction) and D (depression) scales of the GHQ - 28 were more stable than the A (somatic symptoms) and B (anxiety) scales.

Lack of access to early trauma and family dysfunction variables as well as measures of general cognitive impairment at baseline.

They also improved more in general psychopathologic dysfunction and showed greater increases in quality of life.

International and domestic evidence links the mental health impacts of dispossession, the removal of children, loss of culture and a general sense of powerlessness that Indigenous peoples have experienced with the social dysfunction that is evident in some Indigenous communities.

Societal concern about antisocial behaviours of children and adolescents has increased over the years, in part due to the enormous financial costs of youth crime.1 Conduct problems (especially among boys) are the most frequent childhood behavioural problems to be referred to mental health professionals.2 Aggressive and disruptive behaviour is one of the most enduring dysfunctions in children and, if left untreated, frequently results in high personal and emotional costs to children, their families and to society in general.

My experience has taught me that people come to couples counseling because of trust issues, sexual dysfunction, and a general feeling of giving up.