In 2005, Cagan's team created
a general fly model of a human thyroid tumor caused by mutations in the Ret receptor tyrosine kinase gene, then screened a panel of drugs including a kinase inhibitor called vandetanib that suppressed the tumor (Cancer Res, 65:3538 - 41, 2005).
Not exact matches
A
model developed at the
General Robotics, Automation, Sensing and Perception (GRASP) Laboratory at the University of Pennsylvania in Philadelphia can flip, swarm, perch, and
fly through windows.
In 2004 Guilherme Neves and Andrew Chess, now at the Center for Human Genetic Research at Massachusetts
General Hospital, tracked the roles played by other genes on chromosome 21 — in this case using a fruit
fly as the
model.
The synapse between a neuron and a muscle — the neuromuscular junction — of a fruit
fly larva turns out to be a good
model for studying how the nervous system works in
general, which can be applied to other organisms, including humans.