Eventually he suggested that the symptoms he witnessed in these hospital patients were not a reaction to a specific agent of disease but were
a general response to stress.
Not exact matches
Early and lasting
stress can therefore alter the system's
response to stress, affecting in particular the functioning of the immune and inflammatory systems, and the
general health status.
RpoS Is Not Central
to the
General Stress Response in Borrelia burgdorferi but Does Control Expression of One or More Essential Virulence Determinants
The
general nutritional support and the ability
to support detoxification processes and
stress response make it a great choice for you.
By promoting oxidative
stress and depleting antioxidant defenses including the glutathione system, mercury impairs the body's
response to toxicants in
general — including
to mercury itself.
The analyst must seek
to guard himself against this danger as best he can: in part, by dealing with those situations preferably which are not subject
to sudden change; in part, by favoring securities in which the popular interest is keen enough
to promise a fairly swift
response to value elements which he is the first
to recognize; in part, by tempering his activities
to the
general financial situation — laying more emphasis on the discovery of undervalued securities when business and market conditions are on a fairly even keel, and proceeding with greater caution in times of abnormal
stress and uncertainty.»
For instance, the immune system fights infection but with enough
stresses on the body, can cause
general inflammation that kills cells, leading
to greater immune
response and eventually systemic failure.
If the
response involves discussions of the law, one approach a lawyer might take is
to stress that your
response should only be considered as a
general guideline
to the issues raised by a particular question, but that
to provide legal advice you would need
to speak personally
to better understand the particular facts of the case being presented.
These toxic
stress - induced changes in brain structure and function mediate, at least in part, the well - described relationship between adversity and altered life - course trajectories (see Fig 1).4, 6 A hyper - responsive or chronically activated
stress response contributes
to the inflammation and changes in immune function that are seen in those chronic, noncommunicable diseases often associated with childhood adversity, like chronic obstructive pulmonary disease (COPD), cirrhosis, type II diabetes, depression, and cardiovascular disease.4, 6 Impairments in critical SE, language, and cognitive skills contribute
to the fractured social networks often associated with childhood adversity, like school failure, poverty, divorce, homelessness, violence, and limited access
to healthcare.4, 19,58 — 60 Finally, behavioral allostasis, or the adoption of potentially maladaptive behaviors
to deal or cope with chronic
stress, begins
to explain the association between childhood adversity and unhealthy lifestyles, like alcohol, tobacco, and substance abuse, promiscuity, gambling, and obesity.4, 6,61 Taken together, these 3
general classes of altered developmental outcomes (unhealthy lifestyles, fractured social networks, and changes in immune function) contribute
to the development of noncommunicable diseases and encompass many of the morbidities associated epidemiologically with childhood adversity.4, 6
We speculate that next
to genetic transmission problematic parent - child interactions and heightened family
stress associated with parental psychopathology could result in
general dysregulation and related psychophysiological
response patterns in children [82].