Relapse is always a possibility with
generalized demodicosis as there is no easy way to confirm that every mite has been killed but most dogs that relapse do so within a 6 - 12 month period from the time they appear to have achieved cure.
This is quite a contrast to
generalized demodicosis as described below so it is important to be able to distinguish localized from generalized disease.
Relapse is always a possibility with
generalized demodicosis as there is no easy way to confirm that every mite has been killed, but most dogs that relapse do so within a six to 12 month period from the time they appear to have been cured.
Not exact matches
Moxidectin — Few studies are available, but moxidectin (Cydectin injectable — Fort Dodge) given orally at 400 µg / kg / day can be effective in treating
generalized demodicosis.10, 27,28 Moxidectin can be started at a lower dose and then gradually increased to 400 µg / kg / day similar to ivermectin,
as outlined above.
This product was recently evaluated
as a topical treatment for
generalized demodicosis in a small study involving 16 dogs older than 1 year of age.16 Dogs were divided into two equal groups and treated with the spot - on at the proposed minimum dose rate (20 mg / kg of both metaflumizone and amitraz, 0.133 ml / kg) on days 0, 28, and 56 or days 0, 14, 28, 42, 56, and 70.
Juvenile - onset
demodicosis is further categorized
as localized or
generalized according to the extent of the disease.
This spot - on product was evaluated in the treatment of
generalized demodicosis through a multicenter, randomized, blinded field trial during the registration process in Europe.30 Another group of dogs with
generalized demodicosis was treated with daily milbemycin oxime and served
as the control group.
In dogs under 1 year of age, demodex is referred to
as Juvenile - onset
demodicosis, where in adults it is called
generalized adult - onset
demodicosis.
Adult onset
generalized demodicosis is not usually associated with genetic predisposition but sometimes
as a result of other conditions such
as cancer, liver disease, kidney disease or steroid use and therefore may be more difficult to treat successfully.
Categorizing
demodicosis as localized versus
generalized depends on the number and / or location of body sites affected.
As the puppy grows up and his immune system matures, the immune system tends to naturally regain control of their mite infestation; in fact, 30 - 50 % of dogs under age one year recover spontaneously from
generalized demodicosis without any form of treatment.
Often
as generalized demodicosis is treated, the foot is the last stronghold of the mite.
As the puppy grows up and his or her immune system matures, the immune system tend to naturally regain control of their mite infestation; in fact, 30 - 50 % of dogs under age 1 year recover spontaneously from
generalized demodicosis without any form of treatment.