Sentences with phrase «generate better cell»

Not exact matches

The aged egg, which may have had damaged mitochondria that wouldn't work as well, then has fresh mitochondria from the egg precursor cells to generate energy.

Also, it is well - known that body cells alter their extracellular environment by exchanging chemicals, generating heat, and so on.8

They used online advertising and a create - a-video contest (which also generated free media coverage) to drive supporters to a site where they could «Learn more on the go» by surrendering their cell numbers, as well as forward information to a friend via email, download wallpapers and screensavers and of course make a donation.

It had been thriving for well over a billion years when a new kind of cell appeared on the scene, one that harvested the sun's energy using a process that generates a highly toxic by - product — oxygen.

So Novitch worked with Vishlaghi and postdoctoral researcher Momoko Watanabe to refine the protocol to pump up the cells» production and reliably generate better cerebral blobs.

Researchers might generate personalized brain organoids from the reprogrammed skin cells of individuals with, say, schizophrenia and test which medications work best for patients with particular genetic profiles of the illness.

In theory, they're a good option for a physician wishing to generate patient - specific stem cells for potential therapies.

The vaccine generated a pool of TH1 CD4 + T cells (also called helper T cells) that are necessary for an effective antibody response as well as a stable pool of CD8 + T memory cells.

In theory, our work means that you can generate germ cells from iPS cells, which could be very good news for the treatment of infertility.

He added that to the best of their knowledge, no outside group has reported success in generating STAP cells.

While both groups of mice fought off the infection equally well, the second group of mice was not able to generate memory T cells to protect against future infection due to impaired NFkB signals within the cell.

Researchers have successfully used human stem cells to generate functional pituitary tissue that secretes hormones important for the body's stress response as well as for its growth and reproductive functions.

In turn this could lead to the realistic prospect of using SCNT to generate stem cells for therapeutic purposes in humans as well as generating transgenic animals that are healthy, fertile and productive.

Functional expression of the cDNAs in cultured mammalian cells generated receptors displaying alpha - amino -3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)- selective binding pharmacology (AMPA = quisqualate greater than glutamate greater than kainate) as well as cation channels gated by glutamate, AMPA, and kainate and blocked by 6,7 - dinitroquinoxaline -2,3-dione (CNQX).

Chemist Don Gervasio and colleague Sonja Tasic, both at Arizona State University in the US, set out to develop a fuel cell that would generate more electricity for its weight than the best batteries, and would also work at room temperature.

Up until now, efforts in generating a vaccine against TB have been mainly focused on T cells (cells from the adaptive arm of our immune response with memory capacity), with very disappointing outcomes in both pre-clinical as well as clinical trials.

Results of the investigation have numerous uses in the field of hydrogen fuel cell vehicles as well as the chemical industry, as this new method is capable of generating hydrogen from methane gas and electricity in just one step and with near - zero energy loss.

«For a stem cell therapy for Duchenne to move forward, we must have a better understanding of the cells we are generating from human pluripotent stem cells compared to the muscle stem cells found naturally in the human body and during the development process.»

This heat can cause adjacent cells to fail and generate heat, as well, leading to melting materials and fires.

«In combination with recent advances in sorting cells on a biophysical basis, the biomechanical stemness markers we identified hold the potential to rapidly generate corneal transplants with highly enriched stem cell populations, which could one day translate into better outcomes for these patients.»

Technology such as this, scientists said, may have a promising future in the identification and surgical removal of malignant tumors, as well as using near - infrared light therapies that can kill remaining cancer cells, both by mild heating of them and generating reactive oxygen species that can also kill them.

Perovskite solar cells generate electricity just as well when they're made like their simple, silicon counterparts.

Using the spinal cord as a model, Jessell deciphered at the molecular level how different types of nerve cells are generated as well as the steps that drive their assembly into the circuits mediating motor coordination and reflexive behaviours.

Together, the knowledge gained in this project will generate new insight into the pathology of the disease as well as help design future therapies for preventing progressive loss of retinal nerve cells and degradation of vision in glaucoma.

To better discern cell classes and determine how well donor cells integrated into the retina we deliberately generated mosaic eyes.

They instead seem to be a product of natural selection, optimized to generate a favorable degree of genetic diversity, as well as to help safeguard the organism's cells against the kinds of errors that tend to occur most frequently during the process of protein synthesis.

By carefully guiding the cells» choices at each fork in the road, Loh and Chen were able to generate bone cell precursors that formed human bone when transplanted into laboratory mice and beating heart muscle cells, as well as 10 other mesodermal - derived cell lineages.

«The ability to generate pure populations of these cell types is very important for any kind of clinically important regenerative medicine,» said Loh, «as well as to develop a basic road map of human embryonic development.

Finally, I will show how we have combined our results to generate a model of hematopoietic differentiation where specific transcription factors control lineage regulatory regions; our model predicts many already known lineage - controlling factors as well as finds new potential regulators of hematopoietic differentiation such as ATF3 in monocytes and Tcf7l2 and Runx2 in NK cells.

Besides learning many cell biology techniques (tissue culture, Westerns, generating DNA constructs, transfections) as well as fly genetics, students can get familiar with imaging techniques depending on their own interests and experience.

He was also a Fulbright Scholar, and was part of the team that cloned the world's first human embryo, as well as the first to successfully generate stem cells from adults using somatic - cell nuclear transfer (therapeutic cloning).

The ability of adult stem cells to divide and generate both new stem cells (called self - renewal) as well as specialized cell types (called differentiation) is the key to maintaining healthy tissues.

Using the spinal cord as a model, Jessell deciphered at the molecular level how different types of nerve cells are generated, as well as the steps that drive their assembly into the circuits mediating motor coordination and reflexive behaviors.

By decreasing risk factors and harnessing the power of the human immune system, inflammation can be decreased, new cells can be generated and the body can function better.

But new research suggests that adult stem cells may have the potential to generate other types of cells, as well.

He used Microbial Fuel Cells (MFCs) and found what design and conditions work best for generating electricity.

Clinical trials are now underway that aim to see if the large populations of T regulatory cells generated in the thymus can be exploited to better protect against type 1 diabetes.

Several technologies have demonstrated efficacy in generating cell - membrane pores; however, the precise characteristics of those pores (e.g., diameter and duration) have yet be well controlled.

Recognition and utilization of clear and, for the most part mechanistically well understood, criteria will allow the delineation of bona fide miRNAs from the myriad small RNAs generated in eukaryotic cells, allowing for deeper and robust insights into their function, possible mis - regulation, and evolution.

Until panels of well - characterized clinical specimens become available, assay validation will be limited to reagents generated experimentally, such as polyclonal and monoclonal antibodies, XMRV plasmids, and XMRV - infected cells.

«The CREATE system gave us a good hit early on, but we are excited about the future potential of using this approach to generate viruses that have very good cell - type specificity in different organisms, especially the less genetically tractable ones,» says Gradinaru.

The tools are aimed at allowing better access to the data generated by the Human Cell Atlas and make it easier to gain biologic insights from the data.

Existing approaches for culturing those cells have limitations that hamper their ability to generate sufficient quantities of therapeutically active cells using well - controlled processes.

On the other hand, if human material enter the plate of sorted cells while cDNA is being generated, human mRNA will convert to cDNA but with consistent bulk - like expression patterns in the different wells.

A new study, led by Aron E. Lukacher, chair and professor of microbiology and immunology, and Saumya Maru, an MD / PhD graduate student, has uncovered more details about what it takes to generate a good tissue - resident memory T cell response against repeat infections.

In addition to the improved efficacy (increased lifetime of the rainbow PNB), we observed the better selectivity (C4 - 2B versus HS - 5 cells) of the rainbow PNBs compared with the mono - pulse generated PNBs in the same cells (Figure 6A).

Planned to launch in October this year, the freely accessible software developed by the Australian teams will enable researchers to select the best data analysis tools available and properly integrate these data to make sense of the overwhelming amount of information being generated from single - cell studies.

SAY NO TO SUGAR As well as interrupting the transport of vitamin C, sugar generates free radicals and can deplete your cells of essential nutrients.

At some level, the cells hold on to a memory of what they used to be — when made from pancreatic beta cells, which are responsible for producing insulin, these pluripotent cells turn out to be better than their embryonic counterparts for generating insulin - producing cells.

And then also mitochondrial nutrients like extra CoQ10, carnitine, creatine, ribose, you know those type of nutrients that pinch - hit because the parts of your — little cells of your body, these powerhouse cells, the mitochondria, really use them to generate energy and that's a big part of you know, that kind of energy systems you're using when you're running as well.