Not exact matches
A compound called 10β,17β - dihydroxyestra 1,4 dien -3-one (DHED), they found, relies on an enzyme in the brain to be converted from its «prodrug» form into the active form of estrogen; other
organs in the body use
different starting blocks to
generate the hormone.
«Our work focuses on the relationship between form and function in the sound -
generating organs of the
different cricket groups.
«We
generate a pattern of an
organ that we want, creating a 3D hollowed - out structure, stick it on a piece of glass, then we can introduce a lot of
different cell types,» Gillrie says.
Moreover, these stem cell - derived cells released
different amounts of hormone in response to known feedback signals
generated by other
organs in the body.
We capitalized on one of the innate responses of microvascular endothelial cells, i.e., the up - regulation of cell adhesion molecules in response to inflammatory agents, to
generate endothelial cell lines from
different organs.
The selection strategy targeted cell populations expressing the inducible endothelial cell adhesion molecules, E-selectin and VCAM - 1, and proved successful in
generating microvascular endothelial cell lines from a number of
different organs.
First, most currently
generated organoids mainly contain epithelial cells and are void of the many
different cell types that are essential for the morphology and functionality of the whole
organ.
Other cells are multipotent, meaning they can
generate a few
different cell types, generally in a specific tissue or
organ.