Sentences with phrase «generate human antibodies»
«New method to generate human antibodies.»
https://www.sciencedaily.com/ Not exact matches
In the current study, Vanderbilt researchers led by graduate student Andrew Flyak, the paper's first author, used a high - efficiency method they developed to quickly isolate and generate large quantities of monoclonal human antibodies from the blood of survivors of a 2007 outbreak in Uganda who were infected by the Bundibugyo ebolavirus.
The new technology was tested in mice for the ability to generate antibodies in their blood stream that would target human PSMA as well as target PSMA - positive tumors.
«We need more research to investigate the levels of antibodies generated when humans get infected, and how they work in women during pregnancy.
Professor Hayday added: «This is very significant because antibodies make up one of the largest sectors of the pharmaceutical market, and one of the great quests in the pharmaceutical industry is to be able to routinely generate antibodies against human proteins implicated in diseases.
Humans have evolved antibodies against it when we eat meat or are exposed to alpha - Gal - generating microbes in our environment.
New data published in Immunity further illuminate how some human beings generate powerful, HIV - blocking antibodies.
Fascinated by the efficient way the human immune system generates a rapid response to create a near - infinite variety of antibodies, researchers have «hijacked» that machinery and used it to evolve a...
Antibodies generated in humans to DENV are of particular clinical relevance, because they have the potential during a subsequent infection to protect from or increase the risk of developing DHF.
By Day 42, immunized animals generated plasma Abeta antibodies that labeled Abeta plaques in human, AD transgenic mouse and vervet brains; bound Abeta1 - 7; and recognized monomeric and oligomeric Abeta but not full - length amyloid precursor protein nor its C - terminal fragments.
A trpE / apoA - IV fusion protein was generated to produce a goat antibody to human apoA - IV.
WRAIR and collaborators will share data related to assays designed to measure antibody responses following vaccination with ZPIV, biologic samples generated during the performance of animal studies, and biologic samples generated during the performance of early human trials assessing the safety and immunogenicity of ZPIV.
The antibodies listed above in the immunocytochemistry section were also used on eye sections together with a cocktail of antibodies generated against human - specific markers (HSM) to identify human cells (the Oka blood group antigen, mouse TRA -1-85, 1 ∶ 10 (a kind gift from Peter Andrews, University of Sheffield, Sheffield, UK) together with mouse human nuclear antigen, 1 ∶ 1000, Millipore).
So to generate autoimmunity against Neu5gc incorporated in human cells, B cells must first be triggered to form high - affinity anti-Neu5gc antibodies by meeting bacterial pathogens who have incorporated Neu5gc into their cell walls.